Professor of Pediatrics, Thomas F. Boat Chair, Human Genetics, Immunobiology, and Pulmonary Medicine, Cincinnati Children's and Professor of Molecular Biology
Cincinnati, OH; San Diego, CA
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The Quest by Circadian Medicine to Make the Most of Our Body Clocks - The New York Times nytimes.com/2022/07/06/magaz…
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John Hogenesch retweeted
Mignot and Yanagisawa win Lasker prize from @LaskerFDN for discovery of the role of orexins/hypocretins in wake, sleep, and narcolepsy: doi.org/10.1172/JCI211621
In this Viewpoint, Clifford B. Saper @harvardmed places Mignot’s and Yanagisawa’s discoveries in a historical context and congratulates the researchers for “producing the type of ‘touchdown’ in the game of life that every basic scientist dreams about.”
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John Hogenesch retweeted
Paul McCartney is one of the greatest musicians in the history of music.
He was the driving force behind the Beatles and by far the most technically skilled of the four; later, he went on to lead one of the most successful stadium bands of the 1970s, played on and produced several of his own albums, inadvertently invented indie pop, and was the only featured artist on the best-selling album of all time (Thriller).
A multi-instrumentalist, he masters the bass, electric and acoustic guitar, drums, piano, and trumpet, among others.
Not to mention that he’s one of the most virtuosic songwriters of all time, a chameleon across a ton of genres, and that today, at 84, he continues to fill stadiums.
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John Hogenesch retweeted
Dolly Parton’s niece, Hannah Dennison, was diagnosed with leukaemia at the age of 4, and underwent treatment at Monroe Carell Jr. Children’s Hospital at Vanderbilt. The family didn’t know whether Hannah would survive and she received treatment for nearly 4 years.
Hannah did survive and made a full recovery. Dolly believed this showed that miracles do happen. She wrote the song “Chemo Hero” as a tribute to her niece and the medical team. She later returned to the same hospital to perform the song for sick children and surprised the hospital by donating $1 million to its paediatric cancer programme
Rest in peace beautiful soul 💜
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John Hogenesch retweeted
Tell me where Claude and I got this wrong
The U.S. doesn't have a drug problem—it has a $360B+ middleman rebate problem.
List prices are inflated just to fund PBM spreads, fees, and retrospective rebates.
A blueprint to fix it: An Open Federal Formulary + Transparent Cost-Plus
Pricing 🧵👇
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John Hogenesch retweeted
90 years ago today, Jesse Owens won his first Olympics gold medal, he humiliated Hitler at the Berlin Olympics by winning 4 Olympic Gold Medals.
Hitler had hosted the Olympics, intending to be a showcase of Aryan supremacy.
—On August 3, Owens won the 100 m dash with a time of 10.3 seconds.
—On August 4, he won the long jump with a leap of 8.06 metres (26 ft 5 in) (3¼ inches short of his own world record).
—On August 5, he won the 200 m sprint with a time of 20.7 seconds, defeating teammate Mack Robinson (the older brother of Jackie Robinson).
—On August 9, Owens won his fourth gold medal in the 4 × 100 m sprint relay when head coach Lawson Robertson replaced Jewish-American sprinters Marty Glickman and Sam Stoller with Owens and Ralph Metcalfe, who teamed with Frank Wykoff and Foy Draper to set a world record of 39.8 seconds in the event. Owens had initially protested the last-minute switch.
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Wow.
AstraZeneca is in talks to combine with Bristol Myers Squibb in a potential deal that would create a nearly $400 billion pharmaceutical giant, the Financial Times reports.
If it happens, the merger would be one of the largest in biopharma history. trib.al/gmh34h4
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John Hogenesch retweeted
More details on why many sleep and circadian experts favor permanent standard time!
politifact.com/article/2026/…
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Year-round standard time is the way to go. CC .@SRBR_Outreach
Many Americans support switching to year-round daylight saving time to see more sunshine. But doctors and sleep experts say that schedule can disrupt our circadian rhythms and long-term health. Here’s why.
buff.ly/2ck5YPl
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John Hogenesch retweeted
It is with heartfelt sadness that we share the passing of Susan Thompson, PhD, an internationally recognized leader in the Division of Rheumatology at Cincinnati Children's. Learn more about her legacy: ow.ly/Gez250Zs4Tf
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Endorse! washingtonpost.com/wellness/…
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John Hogenesch retweeted
Do not do this
Breaking News: The House voted overwhelmingly to make daylight saving time permanent, but the bill faces an uncertain fate in the Senate. nyti.ms/4wJ6syi
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Anthropic will begin developing drugs, BridgeBio pockets a billion, and more biotech news from The Readout trib.al/aCMg8eC
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John Hogenesch retweeted
Happy 84th Birthday to one of the greatest musicians of our time, Paul McCartney.
No one will ever come close to what he did with The Beatles and his solo career.
Truly an iconic musician🎂🎈❤️
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John Hogenesch retweeted
cc: @jbhclock - *favorite circadian rhythm expert!, 🤓🙏 *H/T & thank you to Dr. @jbrianbyrd for the e-introduction back in the day, 🤓🙏
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