Celeste Karch · Apr 10, 2026 · 12:20 AM UTC

Celeste Karch · Apr 10, 2026 · 12:20 AM UTC

Celeste Karch

Apr 10

Excited to share new work led by Sam Swift in the lab identifying NINL as a modifier of tau seeding alz-journals.onlinelibrary.w…

Integrative genomic and functional analyses reveal NINL as a modulator of tau aggregation

INTRODUCTION Proteostasis dysfunction is a hallmark of frontotemporal dementia (FTD) and Alzheimer's disease (AD), yet the genetic and molecular pathways that disrupt protein homeostasis remain...

alz-journals.onlinelibrary.wiley.com

Apr 10, 2026 · 12:20 AM UTC

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Donna Wilcock · Apr 15, 2026 · 3:22 AM UTC

Donna Wilcock

@Wilcock_v2

Apr 15

Replying to @karchlab @YokoyamaLabUCSF

Congratulations! Great work and thanks for submitting to @alzdemjournals !

Jennifer Yokoyama · Apr 14, 2026 · 5:23 AM UTC

Jennifer Yokoyama @YokoyamaLabUCSF

Apr 14

Replying to @karchlab

Yay @FTDcwow !! 🥳

Caitlyn Fastenau, PhD · Apr 13, 2026 · 2:22 AM UTC

Caitlyn Fastenau, PhD @CaitlynFastenau

Apr 13

Replying to @karchlab

@alzdemjournals

Whitney McGruder · May 6, 2026 · 4:21 PM UTC

Whitney McGruder

@whitneymg

May 6

Replying to @karchlab

Really interesting work on tau biology. Identifying modifiers like NINL adds another piece to understanding how protein aggregation is regulated in neurodegenerative disease.