Here's a link in case you want to read our article online rdcu.be/dnyy8. Enjoy!
New research has established effective benchmarks for RNA sequencing, to support scientists to pick the right tools when investigating gene expression using #longread #RNAseq. Read the WEHI study in @naturemethods: nature.com/articles/s41592-0… 🧵 1/6
4
3
24
5,172
Matt Ritchie retweeted
ScIsoX: a multidimensional framework for measuring isoform-level transcriptomic complexity in single cells. #SingleCell #scRNAseq #Isoforms @GenomeBiology genomebiology.biomedcentral.…
8
16
1,040
Matt Ritchie retweeted
Scnanoseq: an nf-core pipeline for oxford nanopore single-cell RNA-sequencing. #scRNAseq #LongRead #Sequencing #Bioinformatics #Genomics academic.oup.com/bioinformat…
6
13
1,176
Matt Ritchie retweeted
Excited to share our pre-print "γδ T cells modulate anti-tumor immunity in small cell lung cancer" from @Sutherland_Lab! doi.org/10.1101/2025.09.04.6… We demonstrate that γδ T cells are potentially valuable targets for SCLC therapy, especially in a MHC-I low setting. 🧵1/8
2
4
13
1,147
🌏 Make your mark in Melbourne! 🌏 We are looking for innovative researchers to join WEHI as Laboratory Heads and help lead the next wave of biomedical discovery. For more information and to apply 👇 wehi.edu.au/careers/make-you…
5
14
1,449
Part 1 and 2 of the Long-read sequencing Special Issues are now live! tinyurl.com/Genome-Res-LRS
34
98
13,004
Matt Ritchie retweeted
1/: Excited to share our new study led by Luke Zappia on feature selection methods for single-cell RNA-seq data, now published @naturemethods ! We explore how choosing features impacts reference atlases & downstream analyses. 📊📚 nature.com/articles/s41592-0…
1
62
329
21,492
Our new paper examining how to analyse longread RNA-seq with no reference genome. We compare approaches for assembly and downstream analysis, from transcript accuracy to differential expression. Lead by @alexyfyf. Thnx to all contributors incl. @QGouil for the pea data!
Towards accurate, reference-free differential expression: A comprehensive evaluation of long-read de novo transcriptome assembly biorxiv.org/content/10.1101/… #biorxiv_bioinfo
11
28
2,031
⁦Congratulations ⁦@JinNg_1⁩ on being highly commended in the Discovery Award category at ⁦@ResAustralia⁩ Award ceremony 🎉🙌 ⁦@Burr_Lab⁩ ⁦@JCSMR⁩ @WEHI_research⁩ #lungcancer #SCLC
1
2
28
1,575
Matt Ritchie retweeted
Thanks for the opportunity to present our SpatialBench Visium work at #ABACBS24! Happy to hear that RA's will be considered for awards too from next year 😊🙌
1
1
11
618
Matt Ritchie retweeted
We’re hiring! I’m looking for a bioinformatician or post-doc to work on large-scale single-cell data (>13,000 samples) to identify biological variables contributing to molecular variation. Great opportunity working with a fun, talented team @GarvanInstitute. Please RT 1/2
3
24
60
13,684
Matt Ritchie retweeted
Smart Energy Council’s John Grimes has roasted the “Tin Foil Hat Brigade Poppycock” LNP over their Nuclear proposal saying it’s “all about attacking Renewables & boosting Fossil Fuels.” Grimes calls out Dutton’s big list of fibs on Renewables inc his “1.4 Trillion Dollar Lie”🔥
132
932
1,971
154,076
🚨Big news! Five years in the making, our Zebrahub paper is now published in #Cell 🎉. We’ve built a timecourse atlas of zebrafish embryonic development, combining #scRNAseq data and #lightsheet live imaging, and delved deep into the dynamics of key progenitors. cell.com/cell/fulltext/S0092… Explore the datasets here: zebrahub.sf.czbiohub.org Led by @Merlin_Lange with key contributions by @ale_agranados, @Shruthi94Vijay, @jobragantini, @Sarah_E_Ancheta and @yangjoonkim #zebrahub #devbio #cell #Biology #imaging @CellCellPress @czbbiohub #CZBiohubS
16
151
667
83,928
Matt Ritchie retweeted
If you're interested in DNA methylation, Indigenous Genomics and Precision Healthcare, we have a open postdoc position working with @sambuckberry on epigenetic biomarker development. For more information DM me. I'll also be at @abacbs in Sydney (Nov 4-7) if you want to chat
7
11
1,872
Matt Ritchie retweeted
Alice Cleynen from @CNRS @umontpellier delivered a cool presentation on establishing a metric for RNA integrity/degradation in direct RNA sequencing (rDTI) and a method to disentangle technical from biological degradation signals (INDEGRA) ⬇️ github.com/Arnaroo/INDEGRA #ARNA
1
4
638
Matt Ritchie retweeted
Carrying the burden of the first #ARNA2024 talk of the day, @JonathanGoeke from @astar_gis rebooted our brains with a tour de force review of his inspiring work on isoform discovery, quantification, benchmarking and detection of modified bases. Also a champion of #OpenScience
1
5
21
1,550
We present SMINT, a workflow for integrated analysis of spatial transcriptomics and metabolomics - featuring serial sectioning; immunostaining for segmentation; multi-omic registration; and unified analysis at cellular resolution. doi.org/10.1101/2024.10.15.6…
1
7
21
1,138
Matt Ritchie retweeted
Come and join us! We are looking for a bioinformatician to join the lab. Work with single cell, multiome and spatial data from model systems and human samples! Our focus is lymphatics and blood brain barrier in development, regeneration and cancer. seek.com.au/job/79558172
37
43
6,637
Day 2⃣: explore #MachineLearning & AI for #Genomics Ritambhara Singh @BrownUniversity Pengyi Yang @SydneyMaths Sonika Tyagi @RMIT Robert Turnbull @MDAP_Unimelb Jiadong Mao, Sandeep Santhosh Kumar, Xiaochen Zhang @MelbIntGen Ben Goudey @TheFlorey bis.amsi.org.au/register
6
8
1,172
#BioInfoSummer 24 Day 1⃣: Whole cell modelling Prof. Markus Covert @Stanford Dr Megan Coomer #CellBauhaus Dr Adriana Zanca, Dr Lucy Ham, Dr Kaan Öcal, Dr Augustinas Šukys, Dr Sean Vittadello & Dr Michael Pan @UniMelb @vinisalazar_ @MelBioInf Register: bis.amsi.org.au
2
3
660
Matt Ritchie retweeted
Are you interested in sc-spatial multiomics data, motivated by improving patient outcomes in lung cancer, and keen to join a young and growing lab taking single-cell atlassing to clinical applications? Please apply :). We're looking for Postdocs! jobs.helmholtz-muenchen.de/j…
2
41
104
12,219