Smells like corruption

Realsatire. Der nächste Kanzler?

Der nächste Sonnenkönig?

The best part is no part – Semi is the first heavy-duty truck with electric steering, eliminating hydraulic compressors & fluids (which leak & require service) It's lighter, quieter, more precise & redundant by design This also lays the groundwork for future autonomy

Abgehobenheit, die

Lucid mit billiger Tesla Werbung: 😂😂🤦‍♂️

Hat das Enteignungsthema bei @dielinkeberlin eigentlich mal jemand durchgerechnet? Vonovia als Beispiel: aktuelle Ø Bestandsmiete in Berlin ~8,3 €/m². - Bei niedrig angesetzten 25 Mrd. € Entschädigung für 240.000 Wohnungen (Der Berliner Rechnungshof geht beim Verkehrswert von 40–42 Mrd. € aus) - Bei konservativen 3,5 % Zins: ~5 €/m² nur Finanzierung. - Bei Instandhaltung + Modernisierung laut Rechnungshof: ~2,50 €/m². Dazu Verwaltung, Mietausfälle etc. Wir sind also schon ungefähr bei der heutigen Vonovia-Miete – OHNE einen Cent Tilgung. Und dafür 25 Milliarden Euro Schulden und keine einzige neue Wohnung? Wenn schon Schulden, warum nicht mit den Milliarden bauen, nachverdichten, Brachflächen entwickeln – und ja, auch am Rand vom Tempelhofer Feld? What am I missing? Vielleicht verstehe ich’s auch nicht.

As someone who did this kind of genome mining work during my PhD, some thoughts on this Anthropic announcement: First, the very simplified version of what they did is that they noticed two genes (one known, one new) sitting next to a weird repeating piece of DNA. More specifically, they described an unusual reverse transcriptase (RT) associated with a repetitive DNA array and an unknown accessory protein. This kind of process was used to understand CRISPR back in 2002 and was key to the gene editing tools we use today. To put this into context, though, people have been finding RTs associated with CRISPR arrays since 2008, and this general kind of genome-neighborhood mining has been used to discover new biological systems for decades. The basic genome-mining strategy is well established, and there are now mature tools and published pipelines for doing much of this. There are papers that discover and experimentally validate dozens of new systems using this approach in a single study. Doing it in bacteriophage genomes is also nothing new (eg CasPhi). Finding a weird cluster of genes and repeats is often the easy part. The hard part, and where the real discoveries come from, is figuring out what the system actually does. Eg for the bridge-RNA discovery in 2024 from @arcinstitute or the discovery of CasPhi in 2020 from @DoudnaJennifer they figured out the pieces of the system and the rules for what makes it work so it can be used. Anthropic does not yet know what this does. They’ve shown that the repeat array produces RNAs, but not what those RNAs do, what the RT does with them, or whether the system has any of the programmable properties that make the CRISPR comparison justified. I’m genuinely rooting for all of the frontier labs to seriously get into biological discovery, and I’m excited about what comes out of it. But announcing these very early, incremental findings with the framing of a major discovery doesn’t help. I’d much rather they set the bar high now, so that when an AI actually discovers a fundamentally new biological mechanism, everyone appreciates how big a deal it is.

I work in CRISPR discovery research. This is one of the most exaggerated nothing-burgers ever and would be laughed out of the room if a human scientist attempted to publish something like this. (cont.)

Die ersten Grossbestellungen für den Tesla Semi. Bei den aktuellen Dieselpreisen deutlich günstiger!

Climatological history has been made today. With one of the strongest El Niños of all-time in full swing, this is now the first time in 112 YEARS (in other words, since the start of World War I) that not a SINGLE Atlantic Hurricane has formed through September 21st. At the same time, Hurricane Polo in the Pacific Ocean is about to undergo rapid intensification so extreme, it may fall into the 99TH percentile of recorded RI events as the storm attempts to become the 3RD Category 5 Pacific Hurricane of the year.

Die 256GB und 512GB iPhone 18 Pro haben schnelleren Speicher als die grösseren Speichervarianten

❗️ Benchmarks show the 1TB iPhone 18 Pro Max becomes as slow as an SD card due to its QLC memory. The $600 cheaper 256GB model uses TLC and is way faster. HOMOLAB found the 1TB's QLC storage falls from 3,000+ MB/s to an average of 79.4 MB/s once its caches fill, dipping to 1.1 MB/s at 60% full. A 512GB iPhone 18 Pro with TLC beat it in every mixed read/write test, by up to 38%.

LOL

Ein Viertel wählt die Mauermörderpartei!

Just one of the hundreds of scandals at Putin's fake elections today, ballots arrive at polling stations with United Russia pre-filled.

Kenne viele, die sich ein E Auto leisten könnten, mich jahrelang ausgelacht haben, und jetzt am lautesten Jammern…

Ausländische Männer sind gegenüber ihren Frauen und Kindern gewalttätiger als Schweizer. Das anzuerkennen, ist nicht fremdenfeindlich, sondern ein Schritt zur Bekämpfung des Problems. nzz.ch/meinung/haeusliche-ge…

Yes! Bessere Ladekurven!