gene driver, genome jester | Assistant Professor @HebrewU's Insect Genetics Lab

Israel
Philippos Papathanos retweeted
Meet GEValT! Germline Engineering by Viral transduction! No more injections! ReMOT may be obsolete... biorxiv.org/content/10.64898โ€ฆ
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New preprint! ๐ŸฆŸ๐Ÿงฌ We describe draupnir, the only Y-linked gene transcribed during meiosis in Anopheles gambiae and test whether its regulatory sequences can drive expression from the Y chromosome to power a sex-ratio distorter. tinyurl.com/4shvt7tj
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A story that started before the lab moved to @EntomologyHUJI. Great to finally have this out. Challenging Y chromosome genomics and genetic engineering led by @roccodamato83, Elad and Alessia.
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New preprint! ๐ŸฆŸ๐ŸงฌThe key to engineering daughter-killing in mosquitoes isn't what X-linked gene you target with CRISPR. It's when during sperm development you cut it. X-poisoning in Anopheles at last. shorturl.at/T31TG
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Excellent work over many years by Lee Lamdan and many other lab members.
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Philippos Papathanos retweeted
ืžื›ื•ืŸ ื•ื•ืœืงื ื™ ืื—ืจืื™ ืขืœ ืžื—ืงืจ ื™ื™ืฉื•ืžื™ ืœื˜ื•ื‘ืช ื—ืงืœืื•ืช ื™ืฉืจืืœ, ืžืกื—ื•ืจ ื•ื”ืคืฆื” ืฉืœ ืชื•ืฆืจื™ ื”ืžื—ืงืจ ื”ื•ื ื™ืขื“ ื—ืฉื•ื‘ ื•ืžืจื›ื–ื™ ื‘ืœื™ื‘ืช ื”ืคืขื™ืœื•ืช. ืื ื™ ืจื•ืื” ื‘ืชืคืงื™ื“, ื•ื‘ื”ืฆื˜ืจืคื•ืช ืœืฉืจื•ืช ื”ืฆื™ื‘ื•ืจื™, ืฉืœื™ื—ื•ืช ื•ืฆื™ื•ื ื•ืช. ื–ื”ื• ืชืคืงื™ื“ ื”ืžืืคืฉืจ ืชืจื•ืžื”, ื”ืœื›ื” ืœืžืขืฉื” ืœืกืงื˜ื•ืจ ื”ื—ืงืœืื™ ื”ื™ืฉืจืืœื™ ื•ืœื”ืฆืœื—ืชื• ื“ืจืš ืžืกื—ื•ืจ ื”ื™ื“ืข ืฉืงื™ื™ื ื•ืžืคื•ืชื— ื‘ืžื›ื•ืŸ ื•ื•ืœืงื ื™.
ืœื”ื’ืฉืช ืžื•ืขืžื“ื•ืช ื”ื™ื›ื ืกื• ืœืืชืจ ื”ื ืฆื™ื‘ื•ืช ๐Ÿ‘ˆbit.ly/4bFF7p7
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Our latest work with @DipteraAI out now on @biorxiv. We built an open, cheap and accessible mosquito membrane feeder ๐ŸฆŸโš™๏ธ. 3D-Feedies have been a game changer in our insectaries. Hope you'll give it a try: biorxiv.org/content/10.1101/โ€ฆ
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The OpIE2-DsRed marker disrupts blood-feeding in female #Anopheles gambiae #mosquitoes by bending the proboscis. A tweaked OpIE2-b promoter fixes it. Check it out: biorxiv.org/content/10.1101/โ€ฆ
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Philippos Papathanos retweeted
Replying to @BillGates
@BillGates talking about #genedrive as one of the tools in the pipeline that could help end #malaria in the next 20 years @transm0 @TargetMalaria
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Philippos Papathanos retweeted
Seeing what bacteria see from a flying UAV ๐Ÿ‘๏ธ rdcu.be/ehkQB #synbio #biotech @itai_levin @yonchem
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Philippos Papathanos retweeted
Imperial scientists have genetically modified mosquitoes to stop malaria transmission! ๐ŸฆŸ๐Ÿ”ฌ Just a small release of these mosquitoes could make entire populations malaria-resistant We invited @SkyNews to peek in our @transm0 insectary ๐Ÿ”ฝ news.sky.com/story/mosquitoeโ€ฆ
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Philippos Papathanos retweeted
Nicolas Svetec, David Begun, and I wrote a review article about de novo genes. If you are interested in this topic please take a look at this final open-access version @AnnualReviews annualreviews.org/content/joโ€ฆ.
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The coevolution of fungus-ant agriculture science.org/doi/10.1126/scieโ€ฆ Ants learned to farm fungi during a mass extinction - Ars Technica - arstechnica.com/science/2024โ€ฆ
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Philippos Papathanos retweeted
Phew! Really glad to see @VectorBase and @veupathdb back online! @ACME_ASTMH @_SOVE_ @MUVE_ESA
Welcome back! VEuPathDB resources are back online today! We will continue to provide bioinformatics services under a new organizational structure. Read more here: veupathdb.org/veupathdb/app/โ€ฆ
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Philippos Papathanos retweeted
Excited to share that the lights are back on.... for now at least.
Welcome back! VEuPathDB resources are back online today! We will continue to provide bioinformatics services under a new organizational structure. Read more here: veupathdb.org/veupathdb/app/โ€ฆ
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Philippos Papathanos retweeted
My commentary on the closure of @VectorBase. Join me in rallying for its sustainable continuation. Comment, repost, and circulate. Letโ€™s ensure this vital resource remains accessible for our global #VectorBiology research community.
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"Nothing in vector biology makes sense except in the light of @VectorBase... and now the lights are going out. ๐Ÿ’ก๐Ÿ”Œ #SaveVectorBase
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