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The latest episode of the @juanbenet Podcast features @AdamMarblestone, CEO & co-founder of Convergent Research (@Convergent_FROs).
Adam is a leading figure in shaping how ambitious science gets funded and built. In this conversation, he shares that a full mouse-brain connectome — once estimated at $10B — would cost roughly $100–200M today, and that a human one could follow for roughly $1–2B within several years' program: numbers that would have sounded fictional a decade ago. He pioneered the Focused Research Organization (FRO) model — time-bound teams built to produce the public goods that neither academia nor a startup will fund — which has since inspired the NSF's new $1.5B X-Labs initiative.
This conversation is about what's next and what it takes to get there: what mapping a complete mammalian brain could unlock — insights into brain disease, consciousness, how the brain actually learns, and a path to mind uploading. "We badly need a circuit-mapping frontier lab," Adam says of connectomics — a field he calls one of the most neglected, and the one most poised to scale, in neuroscience today.
Full conversation: youtu.be/X0B_GWTuEFo
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Worth catching at @token2049 — @micoolcho on new approaches to crowdsourced robotics R&D.
Heading to Singapore for @token2049?
Our co-founder @micoolcho will be on the stage at Solana Consumer Day to share how we're crowdsourcing robotics research and development on @solana
Thanks @SuperteamSG @SuperteamAU @SuperteamBlack for hosting this summit! RSVP below
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Protocol Labs retweeted
Introducing Griffin, the first model to pass the video Turing test.
48% of people who talked to it live thought it was a real human. Previous systems have had a pass rate <3%. It is #1 on NVIDIA's benchmark for full-duplex AI video.
It’s the first Human Interaction Model (HIM).
Community note
The 48% figure and "video Turing test" claim are from Tavus's own study of 54 one-minute calls, not independently verified or using a standard protocol. Griffin-Lite leads NVIDIA's VideoFDB benchmark on their public leaderboard.
cellcog.ai/blog/tavus-gri…
research.nvidia.com/labs/amri/proj…
tech-ish.com/2026/10/02/tav
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The reading list from @tomoxl’s episode of the @JuanBenet Podcast.
From brain-computer interfaces and human communication to consciousness, powerful mental states, and the future of neurotechnology, here are the books that came up in the conversation.
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4/ Do Androids Dream of Electric Sheep? — Philip K. Dick (1968)
penguinrandomhouse.com/books…
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The @JuanBenet Podcast explores frontier ideas across AI, neuroscience, computing, and technology — with researchers and builders shaping what's next.
🎧 Listen and follow the podcast:
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2/ Oct 11-Nov 1: @JoinEdgeCity, Goa, India
Gather on the coast of Goa to do the best work of the year together.
edgecity.live/india26
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3/ Nov 3-6: @EFDevcon 8, Mumbai, India
The annual global event for the movement building free, open, private, and verifiable systems. This year, it comes to Mumbai.
devcon.org/en/
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4/ Nov 15-17: @SolanaEvents Breakpoint, London, UK
Breakpoint 2026 centers on the Token Supercycle: a new era in which stablecoins, tokenized assets, payments, and AI driven economic activity increasingly move onchain.
solana.com/breakpoint
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Bookmark the PL Events page to stay up to date!
🔗 events.plnetwork.io/map
Here are upcoming highlights.
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1/ Oct 7-8: @token2049 Singapore, Singapore
Get ready to experience a pop-up city, hosting endless immersive experiences and unmissable side events all under one roof.
token2049.com/singapore
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If you’re in Seoul this weekend, join @plcapital's @laceywisdom at @XRPSEOUL for a closer look at how stablecoins are moving into everyday financial use.
I'm moderating the panel "Bringing Stablecoins into Everyday Finance" at @XRPSEOUL (Oct 3) in Seoul this Saturday. Well be digging into two topics that are reshaping how money moves: x-chain liquidity and how neobanks can put stablecoins to work.
This is an especially exciting conversation to have in Korea where mobile-first banks have already shown how quickly people will adopt better financial experiences. Among an incredible line-up of panelists I'll also be joined by @kakaopay_kr one of the neobanks absolutely dominating in this space in the Korean market. Cant wait to share perspectives.
If you're in Seoul, come say hi! 📍 Grand Hyatt Seoul | 6PM
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Protocol Labs retweeted
We're biased but @laceywisdom alone is worth a trip to @XRPSEOUL.
Lacey will be joined by industry leaders like @chandler_agi, Founder of @t54ai, @MonicaLongSF, President of @Ripple, @HugoPhilion, Co-Founder of @FlareNetworks and @JohannKerbrat, SVP and General Manager of Crypto & International at @RobinhoodApp.
Last year 3K+ participants from 40+ countries came together with passion, energy, and community spirit to shape the future of the XRP·XRPL Ecosystem. This year builds on the momentum. 🌍
Please welcome @laceywisdom, General Partner of @plcapital.
Lacey co-leads early-stage investments at PL Capital, focused on backing founders solving real-world problems with decentralized and cryptographic primitives.
She brings extensive experience from Protocol Labs, Eniac Ventures and JPMorgan.
📅 Oct 3, 2026 |📍Grand Hyatt Seoul
🎟 Get Tickets: luma.com/wm5ub5wk
🎙️ Apply to speak: bit.ly/4cteDH2
🤝 Become a sponsor: bit.ly/4wboCI5
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AI is increasingly becoming a tool for advancing frontier science, from understanding biological intelligence to
accelerating work across longevity, molecular nanoscience, and scientific infrastructure.
A wide range of these questions being explored at @foresightinst this week.
Day two of our AI for Frontier & Meta Science workshop is kicking off in San Francisco.
Researchers, engineers, and funders are gathered for talks, working groups, and project building across neuro AI, longevity-bio, molecular nano science, and scientific infrastructure.
Yesterday's speakers included @vivnat (Google DeepMind), @tomoxl (Synchron), @dileeplearning (Astera Institute) and @alex_pentland (MIT Media Lab).
Today: @elidourado (Astera Institute), @Alexteng (Fifty Years), @draparente (Civilization Ventures), @soniaarrison (100 Plus Capital), @stuhlmueller (Elicit), and more.
Powered by @protocollabs, @paradromics, @episteme, and Future Forge Ventures.
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For more on the frontiers of neurotech, AI, nanotechnology, and other emerging technologies, @allisondman and @juanbenet explore where these fields could lead, and the communities helping move them forward. 👇
youtube.com/watch?v=knM7yHFH…
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Prediction markets depend on enough activity to produce useful odds, making long-tail questions difficult to support.
@gensynai is exploring a different approach: using a forecaster model to set an initial probability, with trading then sharpening the market’s odds.
Predict Anything on @Delphi_fyi
Make a prediction
Receive a forecast
Trade the probabilities
No wallet or login required for predictions
Find out more at news.delphi.fyi/p/introducin…
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