Does
@temple really monitor blood flow to the brain, or just the scalp?
In our second validation study, we tested Temple BrainFlow against time-domain NIRS, one of the few technologies that can separate brain blood volume changes from scalp blood volume changes. We had 60 participants go through three physiological challenges: head-down tilt, stand-to-squat, stand-to-supine.
Across all three challenges, Temple BrainFlow tracked brain blood volume at r=0.84-0.91, significantly more than scalp blood volume. The most significant result came from head-down tilt, where Temple's correlation with the brain was 0.91, and scalp correlation was just 0.49.
Key takeaway: Temple tracks the brain, much more than the scalp.
Why this matters: Cerebral Blood Flow responds to almost everything longevity-oriented people already do. It rises with aerobic exercise, and VO2max correlates directly with it. It rises with cold exposure. It rises with meditation. Better sleep sustains it. It drops when you sit for too long. It drops when you are dehydrated. It is one of the most responsive and integrative biomarkers of how well your body is actually running, and aging.
Until now, you could only measure it in a clinical setting, in a single snapshot. Temple measures it continuously, in real time, while you live your life. And Temple is, as of today, the only wearable in the world with validations against brain blood volume, and not just scalp.
This study was guided by our Scientific Advisor, Prof. David Boas, Director of Boston University's Neurophotonics Center, and the mind behind several new, high-impact, biomedical optical technologies in neuroscience, including NIRS.
This is the second modality Temple BrainFlow is now validated against, after Transcranial Doppler. More coming soon.
Link:
biorxiv.org/content/10.64898…
The paper is posted as a preprint and submitted for peer review. We encourage researchers to replicate this. We'll happily loan Temples to any qualified researcher who wants to pressure-test any of our metrics independently.
Cc
@agingroy