Co-founder/CEO @KPL_ApS , Proteomics researcher in Copenhagen, Denmark @UCPH_health @NNFCPR . science, technology, culture, memes and vibes.
Copenhagen, Denmark
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Our latest bioRxiv preprint characterizes our Arg-C Zero protease (available now at kplbio.com/arg-c-zero/ 😏) What you may learn might surprise you!!1!! (ie. equivalent protein group ID's to Trypsin with half the peptide IDs)
#proteomics #teammasspsec
🔬 New bioRxiv preprint: Arg-C Zero, recombinant arginyl endopeptidase with >99% cleavage efficiency, proline-adjacent cleavage, Histone and labile PTMs analysis like ADP-ribosylation and comparable proteome depth to Trypsin.
doi.org/10.64898/2026.05.28.…
#Proteomics #TeamMassSpec
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We have released DIA-NN 2.7. Performance improvements (more proteins) and GUI improvements. In particular, added a data completeness filter for pathway analysis. Further feedback on how to improve statistics and visualisation in DIA-NN is very welcome!
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After OpenAI stole the navier stokes work it is obvious that big orgs and universities will need to have their own AI centers running their private IP just like they have their own supercomputers.
Imagine being a big pharma company using ChatGPT rn.
That is urgent.
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There is a super shady data control setting on everyone's ChatGPT which makes it seem like your data can be used for training even if you explicitly say to *NOT* improve the model for everyone (1/9)
Community note
This claim is false. OpenAI has clarified that the in-app toggle and the privacy portal are independent ways to opt out of data training. You only need to use one method, and OpenAI respects the opt-out choice regardless of where it is set.
x.com/thsottiaux/sta…
help.openai.com/articles/77308…
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A important topic, how to handle the flux of information without going crazy? 🥴🥴 #proteomic #proteomics #TeamMassSpec
A user in our community asks a very important question, is it getting difficult to keep up with the latest proteomic research? Share your experience!
teddit.net/r/proteomics/s/WI…
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We're excited to be hiring an experienced chemoproteomics / surfaceomics researcher to help build new platforms with us at @Deliverome in a joyful, mission-driven environment. Come build at industry speed while making your work openly available for the benefit of all people.
We're hiring a chemoproteomics / surfaceomics Senior Scientist at Deliverome to build a platform that profiles the internalization rate of proteins across the surfaceome. This person will lead from the bench and also explore new technologies for native surface profiling.
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OpenDDE - An Apache-2.0 licensed co-folding method that approaches IsoDDE in performance and beats Proteinix-v2 and ESMFold2🚀
Code - github.com/aurekaresearch/Op…
Paper - github.com/aurekaresearch/Op…
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Cell identity is written in the proteome, not in the DNA, and not always in the RNA. Out on bioRxiv today: The first cell type-resolved, MS-based proteomic atlas of the human body.
biorxiv.org/content/10.64898…
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#TeamMassSpec: any independent data on dual-column LC creating subtle batch effects in LFQ proteomics?
Thinking column A/B intensity shifts, missingness, RT drift, or condition-column confounding. Vendor claims are nice; real-world datasets would be nicer.
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Sci-Hub is an evil website that pirated 85M+ research papers and made them freely available
And now they've added AI to their database to make Sci-Bot.
It answers your questions using latest, full-text articles.
But DO NOT use it. We should all try to make billion-dollar academic publishers richer.
I'm putting the link below so you know how to avoid it.
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The Conehead Praying Mantis probably the craziest insect you have seen all day! | photo by Marta Albareda
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Does identifying thousands of plasma proteins mean more biology? Not always. Over half of 210 published datasets contain contamination markers reported as disease biomarkers.
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I’m looking for an automated way to read others’s scientific data without giving credit or acknowledgement, and also claim full credit for insights from it. And I want it to have a fitting name
OAI: say no more
Introducing GPT-Rosalind, our frontier reasoning model built to support research across biology, drug discovery, and translational medicine.
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teddit.net/r/proteomics/s/gQ…
Latest Bruker or Thermo #TeamMassSpec instrument for #proteomics? Please share your honest experience (anonymously if you want)! Sometimes it is more than just the specs (ie. price, robustness, maintenance, software)
#massspectrometry
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Our latest paper with @atul_deshmukh1 is now out in @JPhysiol. We developed FibeRtypeR to infer muscle fiber type from transcriptome or proteome data. Would be great to receive feedback on it. @TeamDerave @ugent_fge
Paper: physoc.onlinelibrary.wiley.c…
Tool: ccgg.ugent.be/shiny/fibertyp…
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Our latest #proteomics product to top off our Lys-C and Trypsin offerings.
A high quality optimal premix of Lys-C and Trypsin that enables reproducible proteomic analysis!
Make sure to follow @kpl_aps for more exciting news and updates! #TeamMassSpec
🚀 New #proteomics product: Trypsin/Lys-C Premium Mix
With the right formulation, you can add Lys-C and Trypsin together instead of sequentially.
🧪 One tube
⏱️One incubation
📉 Best-in-class missed cleavage rates
🌱 100% recombinant
kplbio.com/trypsinlysc/
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Our recombinant, animal free, sustainable, artisanal 😁 Trypsin is here! High quality and high performance, drop in replacement for any existing #proteomic workflows
Introducing Trypsin RMS - our third product is here.
Recombinant. Methylated. Sequencing-grade.
The robust Trypsin #proteomics labs need, without the batch variability of animal-derived alternatives.
Learn more: kplbio.com/trypsin/
#TeamMassSpec
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It just seems implausible this is what we are made of, essentially, nanotechnology about a billion years beyond anything we can design or make ourselves.
Divinely Designed
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