Professor at @UniofOxford. We use zebrafish to study how cancer starts and spreads.
Oxford, UK
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In defense of basic science - my new video about how we balance basic vs. translational science: piped.video/yl6ETxRfQn8?si=lEim…. . And why we should encourage a culture of wandering to solve problems:. A team effort between @UniofOxford and @OxfordSparks.
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Congrats @leonard_zon and the @ScholarRock team - from bench to bedside (and back again to keep learning more), this is the way it should work.
Every so often, a major event happens in your life to validate years of work. SRRK’s ISEMBYLD was FDA approved. Having participated in its development from basic science to approval, as a physician-scientist, this is one of my best days. Happy for ISEMBYLD to help SMA patients.
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richard white retweeted
Doing a PhD is - at heart - one long discussion with your mentor. The discussion changes over time - with unexpected turns and ups & downs - but through it all is two people discussing a topic endlessly to make sense of it. PhD students: choose someone you like to talk to.
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richard white retweeted
Are you our next Director?
We’re looking for an inspirational scientific leader who is ready to shape the direction of one of the world's leading cancer discovery research centres, a department of the University of Cambridge and core-funded @CR_UK
See: wittkieffer.com/positions/a1…
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richard white retweeted
Really pleased to have been awarded the Buchanan medal from the Royal Society
Four Oxford academics have been honoured in the 2026 @royalsociety Awards. 🎉
Congratulations to:
Prof Laura Herz
Prof Iain McCulloch
Prof Ketan Patel
Prof Charlotte Williams
Read more ⬇️
ox.ac.uk/news/2026-08-26-fou…
ALT Gold coins featuring profile portraits, with inscriptions around the edges. Below, text reads: "Four Oxford academics honoured in the 2026 Royal Society Awards."
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ooh this is very cool!
Neural niches are recurrent features of human cancer that may relay signals to nearby cells, to the immune system, + to the brain. So what’s in these niches, and what happens when cancer cells barge in? We take a look under the hood in our new preprint 1/ biorxiv.org/content/10.64898…
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richard white retweeted
Jim Shorter and his postdoc Miriam wrote a beautiful preview of our most recent paper on mRNA preventing misfolding of IDR-containing proteins.
UTR-ly unexpected: RNA chaperones tame intrinsically disordered proteins: Cell cell.com/cell/fulltext/S0092…
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richard white retweeted
Scientists from MSK and @WeillCornell found that a small subset of T cells, called stem T cells, are responsible for making new T cells and continuously replenishing them in chronic disease.
"We've identified what we believe is a fundamental mechanism, one that the immune system uses broadly to sustain itself in chronic disease," says MSK cancer immunologist Dr. Andrea Schietinger.
Learn more: bit.ly/3TgSLbb
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The ZDM19 meeting in Oxford is coming up soon! We have a great list of speakers, lots of early career researcher events, and an amazing location in the heart of Oxford. Registration is open now but early bird pricing will end soon - so please register as soon as possible! zdmsociety.org/zdm19-registr…
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richard white retweeted
It's a two-fer Tuesday. We are ecstatic to share this preprint from our amazing postdoc @CNFXC. Corey solved a long-standing question in the field of transport biology, identifying SLC16A6 as a melanosomal tyrosine transporter.
Excited to share our new preprint from @RutterLab, identifying a melanosomal tyrosine transporter!
biorxiv.org/content/10.64898…
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richard white retweeted
We are excited to share a new preprint from our amazing postdoc @alexjbott ! Alex designed a new CRISPR screening platform called TRoUT-FISH to identify transcriptional activators and repressors of various genes of interest! Check out his tweetorial below!
Happy to share our new preprint from @RutterLab. To understand how genes are controlled, we developed a method we call TRoUT-FISH, using CRISPR + RNA-FISH. We found that glycolytic gene expression is fine-tuned by lineage specifying transcription factors.
biorxiv.org/content/10.64898…
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This is an excellent review going into thoughts on how and why the neural crest evolved. A great read!
Dear Friends, I just published an insightful review on neural crest evolutionary origin and later transformations.
“Co-option and innovation in neural crest evolution”: science.org/doi/10.1126/scia…
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How does mechanical force influence blood flow? In @NorthTrista new paper, they show it happens through Yap/Taz and Piezo1. Congrats to first author Wade Sugen @sugden_wade and the rest of the team! Check out the link: biorxiv.org/content/10.64898…
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This is such a cool (and important paper). The genome has many ways to diversify beyond the DNA code...
Since the 1960s, the genetic code has been used to predict protein sequences from DNA and mRNA sequences. Our @Nature article demonstrates that these predictions miss thousands of protein sequences present in human tissues.
Across >1,000 human samples, we identified numerous abundant proteins whose amino acid sequences differ from those predicted by the genetic code.
These proteins are not rare translation byproducts. They accumulate to thousands of copies per cell. Some are more abundant than the proteins predicted by the genetic code from the same transcripts.
Their abundance reflects a combination of alternate RNA decoding mechanisms — including codon-anticodon mismatches, tRNA abundance, and RNA modifications — and selective stabilization of the resulting proteins. The last factor – protein stability – emerges as a major determinant of protein abundance across proteins, proteoforms and cell types: slavovlab.net/research.htm#P…
Alternate RNA decoding is pervasive across functional groups of proteins, healthy and diseased tissues. It affects proteins playing key roles in neurodegeneration, and some alternately decoded proteins show strong enrichment in tumors compared to their surrounding tissues.
This discovery has been a long and exhilarating journey with Shira Tsour and the @slavovLab team. It started in 2019 and proceeded through many challenges and thrilling highs. A journey that has opened new perspectives that we long to explore!
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richard white retweeted
This year we started Paper Cuts, where the presenter of the JC will write a short summary of the paper and discussion during the JC. Hyped by the awesome papers presented & trainees’ enthusiastic takes on them. JC Tuesdays are definitely highlight of the week for me! ✨🤟🏻
✨ Continuing our alternate-weekly Paper Cuts series
✨ 2nd Paper Cut of the year - JC by @amishaaab —featuring Cassandras et al., Nature (2026): “Glucocorticoid–FAS axis drives immune evasion in metastatic seeding.”
🔗 nature.com/articles/s41586-0…
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richard white retweeted
It was a privilege to reflect on the life and legacy of Greg Hannon in an obituary published in Cell, co-authored with Julius Brennecke. Collaborating on this was a gift: a chance to reminisce, remember, and try to capture what made Greg so extraordinary. bit.ly/4elZcAU
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A fantastic new #zebrafish model of uveal #melanoma from the lab of @TheKennyLab. This demonstrates the power of modeling rare but difficult to treat cancers, opening up new avenues to understand the biology and find new treatments. It has been really nice seeing this story evolve and congrats on this beautiful work: aacrjournals.org/cancerres/a…
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richard white retweeted
We are looking for a motivated Post-doctoral scholar to really push the envelope in metabolic imaging. Come join our group at MSK!
linkedin.com/posts/kayvan-r-…
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richard white retweeted
Today the melanoma community mourns the loss of Professor Richard Scolyer, AO, a pioneering melanoma pathologist, visionary researcher, and dedicated champion for patients.
Dr. Scolyer, one of the world’s foremost melanoma pathologists and global leader in bridging laboratory science with patient care, transformed how melanoma is diagnosed and staged and helped set international standards that assist how clinicians care for patients around the globe.
MRA was honored to support Dr. Scolyer and his team at the Melanoma Institute Australia through a 2020 Team Science Award focused on improving outcomes for patients with high-risk in-transit melanoma. Their work generated important insights into treatment resistance, predictive biomarkers, and personalized treatment strategies.
After his own glioblastoma diagnosis, Dr. Scolyer remained dedicated to advancing science, courageously helping to pioneer new treatment approaches that may benefit future patients.
We extend our deepest condolences to Dr. Scolyer's family, friends, colleagues, and the entire Melanoma Institute Australia community. MRA is proud to have been part of his remarkable journey and will continue to honor his legacy by supporting the bold, collaborative research he championed throughout his career.
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An Australian cancer researcher who helped develop a treatment for melanoma before using a similar approach to tackle his own incurable brain cancer has died aged 59
timeshighereducation.com/new…
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richard white retweeted
Pioneering Australian doctor Richard Scolyer dies after brain cancer battle bbc.in/4ulquxe
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