Principal Software Engineer, HHMI Janelia Research Campus bsky.app/profile/billkatz.co…

Bill Katz retweeted
Lighting up your screen: a larval zebrafish's cellular activity. Developed by researchers at our Janelia Research Campus, WHaloCaMP is a biosensor that detects calcium signals & offers a window into how cells & organs work together. 🎥 Helen Farrants, HHMI JRC
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Bill Katz retweeted
(1/2) When Janelia set out to map every neuron in the fly brain in 2008, many thought it couldn’t be done. Nearly 20 years later, a complete wiring diagram of the 166,000+ neurons of the adult male fruit fly is helping to reveal the brain’s secrets: bit.ly/4zT7jPf.
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Bill Katz retweeted
New issue is out👉cell.com/cell/current On the cover: the complete connectome of the male adult D. melanogaster central nervous system. The cover depicts a single representative cell from each of the 11,710 neuron types in the dataset, which contains 166,700 neurons in total.
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Bill Katz retweeted
Introducing a complete map of the male fruit fly brain and central nervous system, created in partnership with @HHMIJanelia. With over 166,000 neurons, this is the largest cellular brain map to date. Learn more: goo.gle/4qQTtIW
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We've released the male CNS with lots of papers to follow.
🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them. 🔗 janelia.org/news/researchers…
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Wouldn't it be great if we could not only image large connectomic volumes, but also completely reconstruct them? And if a whole mouse brain project didn't cost billions? With the PATHFINDER preprint (biorxiv.org/content/10.1101/…), we preview a future where it doesn't have to.
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We built an AI model to simulate how a fruit fly walks, flies and behaves – in partnership with @HHMIJanelia. 🪰 Our computerized insect replicates realistic motion, and can even use its eyes to control its actions. Here’s how we developed it – and what it means for science. 🧵
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Domain knowledge (including software engineering) is important in using AI tools for real-world problems.
Some people today are discouraging others from learning programming on the grounds AI will automate it. This advice will be seen as some of the worst career advice ever given. I disagree with the Turing Award and Nobel prize winner who wrote, “It is far more likely that the programming occupation will become extinct [...] than that it will become all-powerful. More and more, computers will program themselves.”​ Statements discouraging people from learning to code are harmful! In the 1960s, when programming moved from punchcards (where a programmer had to laboriously make holes in physical cards to write code character by character) to keyboards with terminals, programming became easier. And that made it a better time than before to begin programming. Yet it was in this era that Nobel laureate Herb Simon wrote the words quoted in the first paragraph. Today’s arguments not to learn to code continue to echo his comment. As coding becomes easier, more people should code, not fewer! Over the past few decades, as programming has moved from assembly language to higher-level languages like C, from desktop to cloud, from raw text editors to IDEs to AI assisted coding where sometimes one barely even looks at the generated code (which some coders recently started to call vibe coding), it is getting easier with each step. I wrote previously that I see tech-savvy people coordinating AI tools to move toward being 10x professionals — individuals who have 10 times the impact of the average person in their field. I am increasingly convinced that the best way for many people to accomplish this is not to be just consumers of AI applications, but to learn enough coding to use AI-assisted coding tools effectively. One question I’m asked most often is what someone should do who is worried about job displacement by AI. My answer is: Learn about AI and take control of it, because one of the most important skills in the future will be the ability to tell a computer exactly what you want, so it can do that for you. Coding (or getting AI to code for you) is a great way to do that. When I was working on the course Generative AI for Everyone and needed to generate AI artwork for the background images, I worked with a collaborator who had studied art history and knew the language of art. He prompted Midjourney with terminology based on the historical style, palette, artist inspiration and so on — using the language of art — to get the result he wanted. I didn’t know this language, and my paltry attempts at prompting could not deliver as effective a result. Similarly, scientists, analysts, marketers, recruiters, and people of a wide range of professions who understand the language of software through their knowledge of coding can tell an LLM or an AI-enabled IDE what they want much more precisely, and get much better results. As these tools are continuing to make coding easier, this is the best time yet to learn to code, to learn the language of software, and learn to make computers do exactly what you want them to do. [Original text: deeplearning.ai/the-batch/is… ]
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Bill Katz retweeted
📢Our latest preprint shows that learning global neuron shapes can help to automatically proofread connectomes and predict neuron types. biorxiv.org/content/10.1101/… Work done in collaboration with @HHMIJanelia, @srinituraga & @HarvardVCG #connectomics #AI 🧵(1/n)
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Our work simulating the fly visual system connectome with @jakhmack @lappalainenjk is now out in @Nature Paper (open access): nature.com/articles/d41586-0… Research Briefing: nature.com/articles/d41586-0…
AI & the connectome are enabling scientists to do what they never thought possible: predict the activity of individual neurons without a single measurement in a living brain. New research led by Janelia’s @srinituraga & @uni_tue’s @lappalainenjk @jakhmack janelia.org/news/researchers…
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Bill Katz retweeted
Genius license plate for a Miata: HTTP 507 (“Insufficient Storage”).
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Bill Katz retweeted
HHMI is excited to announce the launch of AI@HHMI, an ambitious $500 million initiative to accelerate scientific discovery through AI-driven research. Read more about this exciting new initiative at ai.hhmi.org. #AIHHMI
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We're still rebuilding subscriptions (since Amazon abandoned them) and pushing back against the generated submissions on a daily basis. We'd like to keep doing so. The path forward requires us to keep shouting from the rooftops, so... clarkesworldmagazine.com/sub… Thank you!
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A really beautiful day @HHMIJanelia
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What happened last night is something that I thought was only a dream. The strongest aurora ever, above the Dutch windmills. I still can't believe this was real. Captured after midnight in The Netherlands.
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