President, CEO and very proud Professor @ljiresearch La Jolla Institute for Immunology. Women’s health and vaccine innovation. More coffee please.
California, USA
- Tweets 1,556
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Congratulations to Dr. Sujan Shresta @ljiresearch on new funding from @NIAIDNews! Flaviviruses and alphaviruses are spreading — and this #vaccine research is critical
News: LJI Professor Sujan Shresta wins new funding to investigate #dengue and #chikungunya virus vaccines bit.ly/3zGGOlW
#Virology #Vaccines #InfectiousDisease #Health #Arboviruses
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It was an honor to be recognized w/the 2023 Pantheon Award - I’m grateful for the opportunity to contribute to the life sciences and inspire future innovators. As I pass the torch, I encourage you to nominate the next trailblazers here: bit.ly/3YaDBom
#PantheonAwards
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Biomedical faculty search committees, what would you rather have, a candidate with a K99/R00 or a candidate with a career award from the Burroughs Wellcome Fund? A talented physician scientist here has won both, but must give one up. A good problem to have - but which to give up?
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LJI Asst Prof Sam Myers shows how to screen 1000s of post-trans mods to explore biochem pathways and circuits at scale - here, to explore T cell activation. Am beaming with pride at our new recruit and all he is building. @SAMyers_lab @ljiresearch
New from @SAMyers_lab! Combining genome-wide CRISPR–Cas9-mediated base editors with temporally resolved phosphoproteomics enables the functional screening of thousands of post-translational modification sites involved in T cell activation.nature.com/articles/s41592-0…
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Erica OllmannSaphire retweeted
We preset an approach to test phosphorylation site function in high throughput. Like phenotypic CRISPR screens but instead of knocking out a gene, we mutate specific codons with base editors so the resultant protein cannot get phosphorylated that site.
New from @SAMyers_lab! Combining genome-wide CRISPR–Cas9-mediated base editors with temporally resolved phosphoproteomics enables the functional screening of thousands of post-translational modification sites involved in T cell activation.nature.com/articles/s41592-0…
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My kid just committed to a college in Boston. I’m now accepting any and all seminar trips to Boston for the next four years!
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Thank you Dr. Wezgryn @rwegrzyn for your comments at the Women’s Health Action Matters Forum. Yes, we can effect the needed changes for Women’s health in #3not30 years. The faculty of @ljiresearch and the nation are behind you, @ARPA_H and @WHAMnow
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Fun fact, this is me in Barcelona - summer of 2014 - showing off a freebie @Larallbb got me from her new job with the Schoenberger lab @ljiresearch
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A great collaboration with @UCSanDiego and @UCSDCancer
LJI Center for Cancer Immunotherapy and @UCSanDiego + @UCSDCancer scientists make an important advance toward personalized #immunotherapy for all types of #cancer.
Learn more about this #ImmuneSystem research: bit.ly/42WqcAB
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I'm thrilled to welcome Miguel Reina-Campos, Ph.D. (@MReinaCampos) to the @ljiresearch faculty! His #Tcell research has enormous potential for improving #cancer #immunotherapy and more bit.ly/49WrgXs
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Under joint 🤝 leadership of Drs. Vijayanand & Ganesan, @ljiresearch researchers identified #neoantigens in pediatric #BrainTumors and showed that neoantigen-specific T cell gene signatures are linked to better survival outcomes.
🔗 go.nature.com/3S88xRv
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Absolutely beautiful #Ebola cryoET on infected and transfected cells with surprising insights. The most satisfying thing, after 20 years in this field, is how early biochemical puzzles are now fitting together @ReikaWatanabe2 @ljiresearch
We are excited to share our first in situ cryo-FIB-ET manuscript from @ljiresearch in biorxiv! We have revealed the nucleocapsid assembly process and presented the atomic model of the intracellular nucleocapsid of the Ebola virus, which causes highly lethal hemorrhagic fever.
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New on biorxiv, the Ebola virus nucleocapsid has an additional outer layer: NP+genome on the inside; alternating 1-up, 1-down VP24 in the mid; and a newly visualized outer layer of NP held RNA-free by VP35. CryoET @ReikaWatanabe2 #teamtomo @ljiresearch biorxiv.org/content/10.1101/…
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In-cell Ebola NC were in infected (deltaVP30 @HalfmannPeter) and transfected cells + other in-cell views of the Ebola nucleocapsid in the acts of assembly and condensation. Inspired and furthered by @williamnwan Tomo start on @USUKFulbright in @BriggsGroup Thank you ever so much.
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LJI is truly a #compbio powerhouse. Learn how Assistant Professor Tal Einav uses immune cell data to predict how different groups (kids, seniors, men, women) may react to infectious diseases or new vaccines: bit.ly/3PS4LL9 #DataScience #VaccineResearch
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Dr. Grifoni's lab is doing insightful work @ljiresearch
Her #Tcell research changes how we think about immune responses to #SARSCoV2 and other deadly viruses #SanDiego #Immunology
LJI Research Assistant Prof. Alba Grifoni (@Alba_Grifoni) investigates how we might harness #Tcells to better fight #SARSCoV2, #Lassa and more.
"You need to consider both T cell and B cell responses in vaccine design."
Read our Q&A with Dr. Grifoni: bit.ly/46yuTkT
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Very interesting work from @ljiresearch's Drs. Cheroutre, Kronenberg and Myers (@SAMyers_lab) on a process that turns T cells into fighters #InfectiousDisease #Immunology #Tcells
.@ljiresearch Research Reveals Unexpected Role of Nuclear Receptor in T Cell Activity Regulation
Scientists have uncovered a novel role for the nuclear receptor retinoic acid receptor alpha (RARα) in T cell activation. Learn more: ow.ly/iYsQ50PBvVP
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Congrats to @ljiresearch's new Chief Scientific Officer! I'm looking forward to partnering with Shane to build LJI's future #Immunology #Health
#Science News: La Jolla Institute for Immunology appoints Shane Crotty, PhD, as Chief Scientific Officer bit.ly/3OLPWJx
"Shane is an insightful and creative thinker, with an exceptional breadth and depth of knowledge." - @EOSaphire
#SanDiego #LaJolla #Health #Medicine
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Congratulations to Dr. Rinkesh Gupta, the first recipient of the new Michael Croft Fellowship in Immunology #Immunology #LaJolla #ImmuneSystem #Asthma #Ezcema #Allergy
News: LJI and @KyowaKirin_US launch #immunology fellowship program to support early career scientists bit.ly/3OgRcUB
#ImmuneSystem #Health #Medicine #SanDiego #Biomed
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An important look at #pertussis and vaccine efficacy. Kudos to @SetteLab, @Ricardo23349309 and the talented team at LJI's John and Susan Major Center for Clinical Investigation!
Important new #pertussis findings from LJI Prof. @SetteLab and LJI Instructor Ricardo Da Silva Antunes:
bit.ly/3DtjGFE @cellhostmicrobe @CellPressNews #WhoopingCough #InfectiousDisease #Tcells #ImmuneSystem #Vaccines #VaccineResearch
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