Repair after CNS injury is not strictly local! We find that lesion-remote astrocytes (LRAs) exhibit striking spatiotemporal heterogeneity across spared regions of the injured spinal cord and shape neural repair far from the injury epicenter. @Nature bit.ly/3KNUm4D

Glad to share our published version: “ Genetic targeting of premyelinating oligodendrocytes reveals activity-dependent myelination mechanisms”, led by @AksheevB nature.com/articles/s41593-0…

Driving CNS myelination with an approved drug. Fantastic collaboration with Hannelore Ehrenreich and her team at ⁦@mpi_nat⁩ nature.com/articles/s41467-0…

RT @SunLab19: Excited to introduce four new mouse lines described in our recent study @YiheZhang97 (soon available from JAX), including tw…

1/ Better late than never, here’s a long thread of threads summarizing our MOSAIC preprint. If you’re curious about the process by which a new microscope is conceived and brought into the world, this is the thread for you. If you’ve come for eye candy, there’s plenty of that too below. biorxiv.org/content/10.1101/…

You can support the next generation of myelin scientists by funding the Myelin Gordon Research Seminar: my.grc.org/p/contributions/1…. @ubhjkri @MS_Focus @mssociety @NeuroForuMS @SfNtweets @GlialInitiative

Excited to finally have this published! Out today in @NatureComms, we show that following demyelination in a mouse model of Multiple Sclerosis, treatment of senescent microglia with senolytics leads to improved remyelination. nature.com/articles/s41467-0… 1/3

Extremely happy to share our manuscript jointly authored by me and the amazing @LindsayOsso ! An awesome collaboration between the @EthanHughesLab , @denmanlab and Autobahn Therapeutics nature.com/articles/s41467-0… 🧵

Excited to share our work published this week! Led by myself and world class co-first @gdfnunes working in the @EthanHughesLab in collaboration with Dan Denman: nature.com/articles/s41467-0…. A short 🧵

New paper out from the lab! Led by @gdfnunes and @LindsayOsso in collaboration with the lab of Dan Denman. Check it out! 🔬 🐭 🧠 nature.com/articles/s41467-0…

Our 7-year journey on glia-like taste cells is finally published in @CellCellPress! We report how the glia-like cells shape sweet adaptation on the tongue. Huge thanks to our lab members, especially Ghayeon & Geehyun, and collaborators @yulonglilab. cell.com/cell/fulltext/S0092…

New work from Yasmine Kamen shows that differentiating oligodendrocytes are filled with the zymogen procaspase-3. This provides a specific marker for new oligodendrocytes and suggests a role for this pathway in oligodendrocyte fate decisions. biorxiv.org/content/10.1101/…

Online now: White matter aging and its impact on brain function dlvr.it/TG94g9

Cool! Learning-associated astrocyte ensembles regulate memory recall nature.com/articles/s41586-0…

Our work with @schirmerlab in multiple sclerosis (MS) is out today in @NatureNeuro. We investigated lesion progression and cell-cell communication events in MS using snRNA-seq and spatial transcriptomics 🧠 See below ⬇️ nature.com/articles/s41593-0…

Agreed! That's why I wrote ggpubfigs, a ggplot2 extension that *only colorblind-friendly color palettes. Easily make your figures colorblind-friendly with ggpubfigs! x.com/NKWhiteman/status/1852…

🚨 Cues of trained immunity in macrophages of Multiple Sclerosis patients... Curious to know more? 🔍 Dive into our latest paper showcasing the fantastic work by Jennifer Fransson! 🧾✨ #MultipleSclerosis #TrainedImmunity #OpenAcess @InstitutCerveau neurology.org/doi/10.1212/NX…

My second manuscript from graduate school is now on bioRxiv! We generated a comprehensive scRNA-seq dataset of mouse OPCs from young adult to aged animals with the hope of providing a reference dataset for everyone to dig into! tinyurl.com/aging-opcs

nature.com/articles/s41467-0… I am excited to announce our work on how myelin loss culminates in neurodegeneration has been published at Nature Communications. While I have previously covered our findings as a preprint in more detail below, our key findings are: