Assistant Professor @UNC_Lineberger. T cell differentiation during infection & cancer.
Chapel Hill, NC
- Tweets 113
- Following 449
- Followers 410
- Likes 113
Justin Milner retweeted
🕰️🚆🦠 Excited to share our new preprint: “Optimal transport fate mapping resolves T cell differentiation dynamics across tissues”!
We use OT to infer realistic CD8 T cell differentiation and migration trajectories from scRNA-seq timecourses.
biorxiv.org/content/10.64898…
1/
1
6
17
1,178
Justin Milner retweeted
Huge thanks to my my mentors Natalie Stanley (@natstann, @comp_cy) & Justin Milner (@JJMilnerLab) and to my co-authors Genevieve Mullins, Will Green (@greenwilliamd), Huitong Shi, Haidong Yi, and Kay Chung (@HKayChung1) 🙏
10/
1
5
241
Justin Milner retweeted
@biorxivpreprint Optimal transport fate mapping resolves T cell differentiation dynamics across tissues
biorxiv.org/content/10.64898… @JJMilnerLab @UNC_Lineberger @natstann
10
39
1,853
Justin Milner retweeted
@biorxivpreprint Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential @JJMilnerLab @Pratt__Brandon @UNC_Lineberger
biorxiv.org/content/10.64898…
7
22
1,565
Justin Milner retweeted
Amazing work by talented graduate student @Pratt__Brandon and team from the @JJMilnerLab @HKayChung1. Be sure to check it out how they devised a way to unlock the therapeutic potential of CD8 T cells!
Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential biorxiv.org/content/10.64898… #biorxiv_immuno
5
7
499
Justin Milner retweeted
Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment @ImmunityCP @JJMilnerLab
cell.com/immunity/fulltext/S…
21
132
6,060
Justin Milner retweeted
Excited to share the first of many works out of @JJMilnerLab. Be sure to check it out!
Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment: Immunity cell.com/immunity/fulltext/S…
2
13
40
2,561
Justin Milner retweeted
Thrilled we were part of #KSTCells25 @KeystoneSymposia in Vancouver 🇨🇦 and reunited with T cell friends & colleagues! Huge thanks to co-organizers @theLundLab, @Joshilabyale & @DelgoffeLab. We can’t wait for the next one!!
6
38
3,126
Justin Milner retweeted
Delighted to share that our feature selection method for improving inference of cellular trajectories is out today in @NatureComms! Biggest thank you to @natstann @purvislab @WStallaert @JJMilnerLab + team 😊
Paper: rdcu.be/dCVZA . 🧵below.
Super excited to introduce DELVE (github.com/jranek/delve), an unsupervised feature selection method for improving inference of developmental or disease trajectories from noisy single-cell data: biorxiv.org/content/10.1101/… 😊(1/8)
12
33
5,120
Justin Milner retweeted
Thrilled to work with such talented and dedicated group of colleagues!! @derlabunc @YehlabUNC @bryant_kl @JJMilnerLab #adriennecox #ashwinsomasundaran #hjkim
It's World Pancreatic Cancer Day. To all affected by #PancreaticCancer, know that we are here with you 💜 Today and every day, our dedicated team @UNC_Lineberger works to find better ways to treat this devastating disease. #WPCD
3
22
2,089
Justin Milner retweeted
Congratulations @alecplot for winning a best poster award at data science day for work predicting CD8 T-cell fates with @JJMilnerLab :) Truthfully, this a picture from last week, but is the same poster. Great job Alec.
1
5
13
1,323
Justin Milner retweeted
So pleased to announce that @JJMilnerLab has earned our 2023-24 @theNCI SPORE CEP Award for his project, "Molecular regulation of T cell activity in pancreatic ductal adenocarcinoma." Congratulations, Dr. Milner, we're excited to watch your progress this year! @UNC_Lineberger
1
2
19
1,644
Justin Milner retweeted
Happy to share that our story is out! @SciImmunology
Our study demonstrates that sustained CD28 signaling, is required to maintain PD-1+ CD8 T cells during chronic antigen stimulation (1/)
science.org/doi/10.1126/scii…
16
55
226
29,347
Justin Milner retweeted
Paper alert from the @GoldrathLab 🚨 (Link at the end). 🧵 (1/10) >>
8
11
45
9,306
Justin Milner retweeted
Here at UNC M&I, we're proud of our inspiring community of scientists who are changing the way we think about infections! We teamed with @kathaskfilms to provide an inside-look at how they do it. 📽️🔬
Full video: piped.video/yHLFE7oTh7M and at med.unc.edu/microimm/
@UNC_SOM
1
5
12
1,881
Justin Milner retweeted
Finally, @Pratt__Brandon & @JJMilnerLab put these two exciting papers in context with an outstanding @ScienceMagazine Perspective!
bit.ly/Sci_adi3357
5
15
1,369
Justin Milner retweeted
Our work on ENTER is finally out @CellCellPress! Like📱that can 📷📞🎧, ENTER is a modular viral platform that unifies multiple applications:
⭐️Decode Ligand-Receptor interaction
⭐️Receptor-specific cargo delivery
⭐️Link receptor specificity with cell state at single cell
8
97
453
Justin Milner retweeted
Our new preprint is out! This was a collaborative work between us and Dr. D’Imperio Lima at @icb_usp. Later today I will do a thread!
T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections biorxiv.org/content/10.1101/…
2
4
21
Justin Milner retweeted
Have you ever wondered if you could leverage RNA velocity data to better resolve biological trajectories or disease phenotypes?
Delighted to share that our benchmarking study is out today in @GenomeBiology! Biggest thank you to @natstann @purvislab 😊
genomebiology.biomedcentral.…
3
28
109