PhD in biochemistry ➡️ MD @ University of Melbourne | Science writer | (she/her)

Melbourne, Victoria
I truly believe cells/enzymes/etc can smell fear and the concept of "magic hands" is actually just confidence or perhaps positive vibes
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Trying a new protocol for the first time today everyone pray for me
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every so often I rediscover the perfect food item that is the crispy chicken snack wrap from mcdonalds, eat them for lunch multiple days in a row, then get confused about why I feel a bit gross and tired
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(malnutrition)
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you guys don't know how much I am exactly the target audience for the new Nathan Fielder Elizabeth Holmes documentary
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this whole thread feels like im in one of those videos where someone's saying all my favourite words as a prank
More broadly, our findings reveal how tissues match🔗 #immune_support to #metabolic_demand . Understanding this dialogue 🗣 may help explain how disrupted mitochondrial or immune function contributes to tissue decline in aging and metabolic disease.💡
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survived another melbourne winter AND my final med school exams with only a handful of career-threatening crashouts 💚
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Crazy of me to have posted this the same day the Western blot antibody stuff really kicked off
Is anyone still talking about the reproducibility crisis or did we decide it was just all too hard?
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Is anyone still talking about the reproducibility crisis or did we decide it was just all too hard?
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Khalia 🩺🧬 retweeted
Fake news. Next, they'll tell you there is no such thing as the luckiest thermocycler in the lab
#MicrobiologyMonday: Bunsen burners are used to reduce airborne contamination. Data in #JournalSpectrum suggest the practice is not evidence-based and, except in some cases, Bunsen burners can be removed from practice w/o compromising research integrity. asm.social/33D
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I just ran my first PCR in like 4 years and it?? worked perfectly?? I'm genuinely floored
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I'm using weird primers I designed myself to add a bunch of stuff at the 5' end, am using cDNA as the template instead of a plasmid.... This shouldn't have worked
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Today I'm feeling v grateful I got the opportunity to do med school post-PhD. I've learnt so much and understand the context for my PhD work so much better now. There should be more opportunities for PhD students to get exposure to the clinical environment - I've found that intricate knowledge of a mechanism is most useful when placed in context.
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Mileage may vary for non-biology PhD students, to be clear
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Khalia 🩺🧬 retweeted
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This has been a thing for ever and ever - I literally don't even look at the vendor's figures when buying antibodies/ELISAs/etc because they cannot be trusted. We rely entirely on word of mouth recommendations and (costly) in-lab optimisation/validation, and kind of just accept this behaviour as normal. I would save a heap of time and money if someone could please sort this out 😅
Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures", but their own internal data.
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I'm so excited to be part of the first @PrimordiaGrants cohort! I've been trying to get this idea out of my brain and into the lab for a while now. We're performing a high-throughput experiment to validate targets that can reprogram macrophage function under hyperglycemic conditions - hopefully the first step in a much longer term tissue regeneration project. Stay tuned to see how it pans out!
Primordia Grants Cohort 1 is here! $13,200 funded across 7 projects. Researchers from 6 countries doing science that matters. A collaboration between @valley_dao and @BiopunkLab Here's the full cohort 👇
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Khalia 🩺🧬 retweeted
Nothing wrong with using AI to analyze your genome but please do not naively believe AI based analyses of genomic information without consulting clinical geneticists, physicians & genetic counselors. Lots of snake oil salesmen in this space.
On @TuckerCarlson we talked a lot about this, why genetics — despite it being the greatest preventative medicine tool ever — has been so under appreciated for so long. Our customers more and more are using the data they get from Nucleus alongside AI for amazing health insights (all raw data is available to all customers in a simple download format, they usually port that over into Claude seamlessly).
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