Building AI infrastructure for science. Professor in economics. @DeSciClaims @SciWeave

Luzern, Switzerland
Bittensor is not perfect. But it's one of the smartest, most ambitious projects out there.
OPEN MINDS A short film about Bittensor $TAO
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We're using an open competition to structure scientific knowledge in a machine-optimized format. And the intense competition is leading to rapid improvements in data quality! #science
A core thesis behind Claims is that an open competition will create better results than any in-house process. Our production data is already validating that thesis - in less than 4 weeks! Our measure of data quality is the % of miner-submitted claim-evidence pairs for a given paper that: (1) deviate from our own pipeline and (2) were unanimously evaluated as an improvement by two independent judges who can't see who submitted. That quality benchmark has increased from 70% at launch to 94% now. This happened even though we made our judges MORE critical over time and capped the number of claims any miner can submit to 10, making it much harder for miners to get their work accepted into our Silver record. The competition is working. Our miners are brilliant. The next big step is coming soon.
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Philipp Koellinger retweeted
“The product is validated data. We’re going to the companies we’re already talking to and enriching their data with ontologies that match their particular research questions, adding greater value.” @DeSciClaims appeared on @SubnetSummerTAO yesterday, breaking down how the subnet’s key product is to enhance data for others, through one-time fees and regular subscriptions where incoming and relevant information is consistently fed, sharpening their research. Watch the full podcast to learn about roadmaps, architecture, and incentives.
🚨 Subnet Summer AMA x SN111 @DeSciClaims - NOW LIVE ON YOUTUBE We covered: - What SN111 Claims is and why making science machine-readable matters - The DeSci opportunity: $3 trillion of knowledge locked in human-readable papers - How miners extract claims, how validators audit for integrity - The product roadmap: turning a knowledge graph into a revenue-generating API If you're interested in decentralised science, AI-driven research infrastructure, or how Bittensor tackles knowledge accessibility, this one's for you. piped.video/9bOyBIJprro?si=lFJg…
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If you're curious about what we're building at @DeSciClaims, check out this podcast. Fun convo with @SubnetSummerT
🚨 Subnet Summer AMA x SN111 @DeSciClaims - NOW LIVE ON YOUTUBE We covered: - What SN111 Claims is and why making science machine-readable matters - The DeSci opportunity: $3 trillion of knowledge locked in human-readable papers - How miners extract claims, how validators audit for integrity - The product roadmap: turning a knowledge graph into a revenue-generating API If you're interested in decentralised science, AI-driven research infrastructure, or how Bittensor tackles knowledge accessibility, this one's for you. piped.video/9bOyBIJprro?si=lFJg…
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Philipp Koellinger retweeted
23 clinical trials had tested whether switching off a woman's ovaries helps her survive #BreastCancer. But not one could tell whether it adds anything on top of the drugs she is already taking. These cancers are fed by oestrogen. Before menopause the ovaries are the main source, so they can be taken out with surgery, closed down with radiation, or switched off with drugs. The drugs are chemotherapy and tamoxifen. Chemotherapy kills dividing cells. Tamoxifen stops the cancer from responding to oestrogen. Earlier reviews had found no clear benefit from switching off the ovaries. So the Early Breast Cancer Trialists' Collaborative Group went back for the individual records: what happened to each woman, rather than each trial's summary results. 18,851 women. That is 98.9% of every woman randomised in eligible trials of this treatment. The oldest trial began enrolling in 1948, at the Christie Hospital in Manchester (@TheChristieNHS). It was the first cancer treatment ever assessed in a randomised trial. Its long-term survival data came from @NHS records. The women were typically in their early forties when they joined, and were followed for more than a decade. The result, among women who were under 45 when they joined and were already taking tamoxifen: 9.1% of those who also had their ovaries switched off had died of breast cancer within ten years. Among those on tamoxifen alone, 11.7% had. In the older trials, where none of the women received tamoxifen, the gap was wider. Cancer came back within 15 years in 39.1% of the women whose ovaries were switched off, and in 56.5% of the women whose were not. Switching off the ovaries has costs. The women whose ovaries were switched off had consistently more severe hot flushes than the women whose were not, and it is known to cause bone loss, which can be monitored and managed. Only 4 of the 23 trials measured quality of life at all. Across the trials there was no increase in deaths from other causes, and none in second cancers. This paper went through Claims this week: 8 adjudicated claims, each tied to its evidence. This is the shape of question we want a claim-evidence graph to surface: 23 trials, one claim between them, and no single paper that settles it. Getting the answer still needs the individual patient records, the original investigators and a national mortality register. The Claims database and AI do not produce that part. But they can point to where someone should look.
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One of the first 1000 papers processed by @DeSciClaims after our mainnet launch last Friday
Your liver gets the blame for your cholesterol. But part of the instructions come from your brain. MC4R is a receptor in the brain that regulates appetite. About three in a thousand people carry a broken MC4R gene copy, and they gain weight early and heavily. Researchers at @Cambridge_Uni and @unige_en compared these carriers with 336,728 people in the @uk_biobank. Correcting for the weight itself, the carriers had lower cholesterol and triglycerides. A meal test caught the same effect in real life. 11 carriers, 15 controls matched for weight, a 674 calorie meal at 60 percent fat. The triglyceride spike was about half as big in the carriers. In the same biobank, common obesity built from many small variants carried clear extra heart risk. Obesity from this one broken receptor showed no detectable increase in that risk. Same weight on the scale. Different consequence, depending on the route that produced it. Zorn et al., @NatureMedicine 2025. doi.org/10.1038/s41591-025-0… This paper went through Claims this week: 8 claims, each tied to the evidence behind it. @Farooqi_Lab
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Philipp Koellinger retweeted
Ep. 99 - Philipp Koellinger & Christian Roessler Philipp and Christian are building Claims @DeSciClaims Subnet 111 Timestamps 0:00 - Highlights 1:48 - Proof of Pitch to Mainnet in Three Months 2:50 - Why Economists Find Bittensor Fascinating 3:42 - Citations as Science's Reward Function 4:29 - The Replication Nobody Would Publish 6:53 - How Much Published Science Is Wrong 8:26 - The AI Echo Chamber vs. Human Work 9:54 - Making 300 Million Papers Machine Readable 15:11 - Reproducibility vs. Citations 15:46 - Turning Papers Into a Knowledge Graph 16:20 - Why LLMs Hallucinate Citations 21:21 - Longer Context Windows Make This Obsolete? 22:56 - Coverage, Extraction Quality & Evidence Quality 25:16 - What Counts as a Substantive Claim 26:42 - What This Is Worth to Working Academics 27:37 - Academia Admits the System Is Broken 29:26 - How Do You Actually Find the Truth? 32:06 - Truth as Probability, Not Zero or One 33:33 - Logical Proof vs. Physical Replication 35:44 - Correlation vs. Causality 36:28 - Ground Truth From Replication Studies 38:12 - Codifying Claims to Surface Contradictions 40:14 - Can You Trust an LLM as a Judge? 42:48 - Synthetic Checks: Truth Is Sparse 45:40 - How Much Miner Variance Is Desirable 46:55 - Why Bittensor Instead of a Closed Company 49:50 - Success, Revenue & the Palantir Comparison 51:47 - The Flood of AI-Written Papers 54:36 - Advice for Discerning Truth
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This is the best explanation of #Bittensor I've seen so far. I read this aloud to a friend and it's the first time I got a "ah, now I understand why you're so excited!"
Okay, consensus is that this is pretty good, so I've given it a perm URL: pill.taobubbles.net For the web-based, simple-stupid explanation of Bittensor for your normie friends. Send it around!
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Philipp Koellinger retweeted
Claims V0 is live on mainnet. Here’s how mining works. Every six hours, Claims puts ~50 scientific papers in front of 10 competing miners. Miners extract the claims and evidence. Validators test the work. The strongest batch earns the most weight. Here’s the full loop. 🧵
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Science friends, come join us! Set up a miner with your Claude on SN111, turn the scientific literature into a verifiable knowledge graph, and earn!
Claims is live on mainnet. Miners now compete to turn papers into structured claims and source evidence. Validators score the work. The best work earns the weight. Each round builds the canonical graph of science. 450 testnet papers led here. Day 0 starts now.⏱️
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Philipp Koellinger retweeted
Everyone's worried about AI hallucinating sources for its facts. But that's the easy half of the problem. The hard half: when a cited paper is real, knowing whether the finding inside is too. One landmark study is titled, literally, "Why Most Published Research Findings Are False." When a pharma company went back to reproduce dozens of high-profile results, most didn't hold up. P-hacking, underpowered studies, failed replications buried in the file drawer - the errors are baked into the record itself. Retrieval doesn't solve this. It hands you the paper and repeats what the author said. It can't tell you the result was contradicted three times since, or never replicated once. And the pile keeps growing. Since ChatGPT, the rate of new submissions has increased by ~50% - more claims stacked on the same broken foundation. That's what Claims exists to fix. Not just "find the paper," but map every claim, the evidence for and against it, and how much of it actually survives contact with the rest of the field. 👉 Follow our progress on Discord: discord.gg/phE5N3uT
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This is one of many reasons why decentralized alternatives such as @bittensor are so important.
The US government, citing national security authorities, has issued an export control directive to suspend all access to Fable 5 and Mythos 5 by any foreign national, whether inside or outside the United States, including foreign national Anthropic employees. The net effect of this order is that we must abruptly disable Fable 5 and Mythos 5 for all our customers to ensure compliance. Access to all other Claude models is not affected. We apologize for this disruption to our customers. We believe this is a misunderstanding and are working to restore access as soon as possible. Read our full statement: anthropic.com/news/fable-myt…
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Philipp Koellinger retweeted
Subnet 111. Live on #Bittensor ⚡ Science has a credibility problem. Papers get published. Results can't be replicated. Nobody gets held accountable. Claims is changing that - using Bittensor to score, verify and surface research that actually holds up. Led by Prof. Philipp Koellinger [ @PKoellinger ] and Prof. Christian Roessler: 17,000+ citations. Published in Nature and Science. Game theorist specialising in mechanism design. Built @DeSciLabs to improve research incentives. They won Proof of Pitch. They impressed the judges. They earned the community. Now they get a subnet.
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Philipp Koellinger retweeted
Bittensor's co-founder just said something that stopped me cold. He and his co-founder built the entire protocol from scratch. And then the subnets started moving faster than both of them combined. His exact words. People far smarter than us have started building on top of the system. The founders do not develop subnets anymore. The network outgrew them. Now read why that sentence is the most bullish thing anyone has ever said about $TAO. Bitcoin's creators did not build every application that runs on Bitcoin. They built the incentive layer and got out of the way. The network grew into something far beyond anything two people could have built alone. That is exactly what just happened to Bittensor. Decentralised training producing more resilient models than centralised alternatives. Subnets beating state of the art benchmarks domain after domain. Corporations like Unity pulling 3D objects directly from Bittensor for commercial video games. DeepMind researchers publicly acknowledging that decentralised training produces stronger more generalised models. All of it happening without the founders directing any of it. TCP/IP does not need its inventors to maintain it anymore. The internet ran past them decades ago. Bittensor just crossed the same threshold. Two founders watching the protocol they built outgrow them in real time is not a red flag. It is the oldest signal in technology. The people who recognised that moment in Bitcoin did not need to explain themselves later. The people who recognised it in Ethereum did not either. This is still early. The people who read the docs always buy before the people who read the price. Screenshot this.
Two people who were early in Bitcoin and early in Ethereum just went on record about $TAO. One of them wrote a book about Bitcoin in 2013. The other invested in the Ethereum ICO in 2015. Both of them started a fund with Jason Calacanis with a single thesis. Bittensor is the third great open-source substrate after Bitcoin and Ethereum. Here is the exact framing they used. In the early 90s Microsoft, AOL, and CompuServe were the well-capitalised incumbents. Everyone thought they would monopolise and run away with the internet. Then TCP/IP, Linux, and the World Wide Web came along and everything converged on an open-source substrate. Bittensor is that open-source substrate for the AI story playing out right now. OpenAI. Anthropic. Google DeepMind. XAI. Different cast of characters. Same pattern. And this time you can actually own a piece of the open-source substrate. Now read the valuation mismatch that should stop you cold. The four main AI labs combined are worth approximately $1.5 trillion. Bittensor is worth $1.7 billion. Ridges subnet competes directly with Claude and Cursor and has beaten them on benchmarks. Ridges market cap is $30 million. Cursor is worth $30 billion. That is not a small dislocation. That is a comical one. The highest valued subnet in the entire ecosystem is around $80 million. There has never been a billion dollar subnet yet. On Ethereum during the ICO mania projects with nowhere near this quality of output were raising hundreds of millions within minutes. Now think about how many orders of magnitude more capital is chasing AI opportunities today compared to 2017. When that capital discovers Bittensor the valuation rerating will be violent to the upside. Their exact words. Not mine. The man who called $TAO at $3,000 by end of 2026 said it directly. By 2030 it will be a trillion dollar ecosystem. Every molecule in my body is screaming this is another one. The people who read the docs always buy before the people who read the price. This is still early.
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You can still get into our new Claims subnet at discounted early investor conditions. @DeSciClaims #Bittensor
Paris saw @DeSciClaims win Proof of Pitch. 🏆 But the crowdfund isn't over. Both teams still need your support to power their launches on Bittensor. If @provenonce_ai doesn't secure a subnet, all pledged TAO will be returned. Back a team ↓
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Philipp Koellinger retweeted
The judges voted. You voted. After 45 minutes live at the Louvre, @DeSciClaims had raised 184 TAO. Claims wins Proof of Pitch at @proofoftalk 🏆 And now they're launching a subnet on Bittensor - auditing the science that the world runs on.
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Pitching our new baby @DeSciClaims at @proofoftalk in the Louvre and WINNING this adrenaline-raising competition was such an honor. Joining the amazing @bittensor community as a subnet owner is literally a dream come true for me. Pitch deck: bit.ly/4odS2TS
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Super excited to speak at the @bittensor track at @proofoftalk on Tuesday at 6pm CET! @bitstarterAI will we streaming this live, so fell free to join!
At this year’s Proof of Talk, DeSci will be part of the center-stage conversation. Our scientific advisor @PKoellinger, founder of DeSci Labs, will be on stage in Paris discussing how Bittensor can help create infrastructure for verifiable scientific claims. We believe distributed compute can become a real engine for science by scaling reproducible workloads, aligning incentives, and rewarding useful scientific work. Philipp has been building toward this future for years, and we’re excited to see him bring that vision to Proof of Talk. Keep an eye out for his talk!
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