Laboratory for Precision Neuroimaging @UCSF. PI’s: @rahuldesikan, @leosugrue. We study brain disease using imaging, genetics, health, and behavioral data.
San Francisco, CA
- Tweets 11
- Following 67
- Followers 123
- Likes 5
Center for Precision Neuroimaging retweeted
Dr. Rahul Desikan & his team at UCSF @PrecisionNeuro are building a free online genetic platform for #ALS patients to calculate genetic risk. bit.ly/2C3tbMl
1
3
9
Center for Precision Neuroimaging retweeted
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration. Beyond APOE, polygenic hazard scores in living subjects were associated with amyloid deposition and neurodegeneration in susceptible brain regions. bit.ly/2Nex6dG @rahuldesikan @ADNI3study
1
11
13
Center for Precision Neuroimaging retweeted
'Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration' --> New #research from the @PrecisionNeuro team. bit.ly/2BcPj6G
1
3
"...these findings further suggest a nuanced relationship between polygenic risk and markers of amyloid deposition, pathological tau and neurodegeneration"
new work from my lab on polygenic risk and #Alzheimer's @UCSFimaging @UCSF @UCSFmac
academic.oup.com/brain/advan…
2
2
Center for Precision Neuroimaging retweeted
This is my own genetic data run on our tools - looks like I'd benefit from stem cells and oxidative therapies - this is the real potential for #Genomics for #ALS #treatments - we can do this and any #PALS #fightALS
6
11
49
Center for Precision Neuroimaging retweeted
'Partitioning the genetic architecture of #ALS.' New results from @PrecisionNeuro via @biorxivpreprint --> bit.ly/2GRDGXX
4
3
Center for Precision Neuroimaging retweeted
new work from my laboratory
CXCR4 involvement in neurodegenerative diseases. Multi-modal findings suggest that abnormal signaling across a ‘network’ of microglial genes may contribute to neurodegeneration. go.nature.com/2V7LWq6 @karchlab @rahuldesikan
1
3
16
Our new findings suggest that subsets of ALS patients are at elevated genetic risk for FTD, cardiovascular, or immune dysfunction. Developing multiple pathway polygenic scores in this regard would be important for informing therapies.
unveiling the genes underlying #ALS - we show how #genes can help you find therapies that may work for you:
biorxiv.org/content/early/20…
2
3
3
Ten observations about ALS! Which of these were unknown to you? #ALS
1
Welcome to the official page of the Laboratory for Precision Neuroimaging @UCSF! Led by Drs. Rahul Desikan @rahuldesikan and Leo Sugrue @LeoSugrue. Please follow us for major updates and news from the lab!
2
4
GWAS for dummies
Hello! I have written an explainer on genome-wide association studies and genetic risk.
vox.com/science-and-health/2…
Working on this story made me feel like my brain was going to explode.