Avi Roy
@agingroy

Science Lead @temple. Biomed Scientist in #longevity. Mentor & Investor in Health startups. Past CTO @BioVivaScience, Researcher @CASMIORG, Founders Health.

 Oxford, England
temple.com/
Joined May 2008
1,105 Photos and videos
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The Obesity Pill Era Starts Now

Obesity medicine just crossed a threshold. Weight-loss pills now work well enough to matter. The more useful question is what changes when treatment moves from the injection pen to the medicine

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7 Drugs. 30,000 Mice. 20 Years. The Only Longevity Compounds With Real Evidence.

The longevity supplement market hit $85 billion in 2025. Most of it is noise. The NIA Interventions Testing Program has been quietly running the most rigorous longevity drug trial in history since

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What a Dying Baby Taught Me About AI's Actual Purpose

In 2023, a newborn at the Children's Hospital of Philadelphia presented with symptoms that didn't match any standard diagnostic pathway. She was dying, and nobody could tell her parents why. Let's

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One Receptor. Two directions. Total Control Over Sleep.

In 1998, two research teams independently discovered the same molecule within months of each other. One group named it hypocretin. The other called it orexin. Both names stuck. The discovery would
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Resistance training beats cardio for sleep. Here's the data most people haven't seen

You've probably heard that exercise improves sleep. You've probably also assumed cardio is the best type. Run more, sleep better. Swim laps, knock out faster. The advice sounds reasonable. It's also
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This drug dropped triglycerides 38.5% in 14 days (and it's not a statin)

For decades, scientists tried turning on a receptor in your liver to fix cholesterol. It backfired every time. Triglycerides shot up. Trials failed. Then researchers at EPFL tried something nobody
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Why Longevity Is Now a Scaling Problem, Not Just a Biology Problem

TL;DR @elonmusk's latest Moonshots interview with @PeterDiamandis reframes longevity as infrastructure, not just molecules. Key claims: AI diagnostics already in consumer use (Musk uploaded his MRI
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A Drug That Doubles REM Sleep Without Adding Sleep Time: What We Know (And Don't)

TL;DR A Phase 2 epilepsy trial found BMB-101 increased REM sleep by 90% (56→107 min) without changing total sleep time Unlike benzos (suppress REM) or orexin blockers (add sleep time), this drug

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The Cold Medicine in Your Cabinet Probably Doesn't Work

Not expired. Not counterfeit. Just... ineffective. Exposed by science after 90 years on pharmacy shelves. The active ingredient in Sudafed PE, NyQuil, Mucinex, and 250+ other products was declared no
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Comprehensive Medication Protocol for Extending Lifespan: Evidence-Based Guide

Thirteen key medications—identified from rigorous mortality data across 500,000+ adults—provide a comprehensive pharmacological approach to extending lifespan by targeting every major biological
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Silencing the Genetic Heart Time Bomb: Revolutionary Therapies Target 1 in 5 People's Hidden Risk

📊 Lp(a)-Lowering Therapies: Latest Developments For the 1 in 5 people with elevated lipoprotein(a)—a genetic risk factor unaffected by diet or exercise—several promising therapies are advancing
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The Silent Keepers of Cellular Order: How Your Body's Cleanup System Controls Aging and Cancer

Every second of every day, billions of your cells are committing suicide. This isn't a bug - it's a critical feature of multicellular life. But what happens to all these cellular corpses? The answer
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