I'm hosting a dinner next month in Boston for scientists and engineers interested in safely increasing human intelligence. I'm interested in both treating cognitive impairment and helping healthy people improve their cognitive abilities. Could we develop treatments that help people learn faster, reason better, and solve harder problems? I'm especially interested in approaches that could work in adults. There's a lot we don't know, including what's possible and what would be safe. I'd like to bring together people across neuroscience, genetics, drug development, and computational biology/ML to discuss promising research and what it would take to turn it into useful treatments. I'm also interested in backing the right founding team if one comes together. If you're working in this area or have relevant expertise, please apply at the link below. Happy to cover travel if needed. Or if you can't make it to Boston, let us know - I may host one virtually for those who can't attend in person.

Sep 22, 2026 · 10:21 PM UTC

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Replying to @brian_armstrong
Highly recommend talking to the team at @CapableLabs; their entire mandate is to push the boundaries of these kinds of human capabilities. @isaakfreeman and @helenarose are brilliant founders and their speed of execution pretty unmatched in bio.
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Replying to @brian_armstrong
@Kevin_McKernan - Maybe you’re interested in @brian_armstrong ‘s Boston dinner for scientists?
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Replying to @brian_armstrong
I’ve always had a good memory but when I was 12 I came across the book “How to Develop a Superpower Memory” by Harry Lorayne. In this book he delves into the topic of mnemonics. Each chapter covers a different aspect such as lists, foreign languages, faces, cards, et cetera. Before reading the book I would always lose my glasses and constantly look at my watch because I’d forgotten what it said the last time. After reading it I couldn’t forget where my glasses where nor what time it was when I last looked at the watch. I also couldn’t forget where I had placed anything. His techniques helped me remember phone numbers and French, Russian and Spanish words. I was in a meeting once when the big boss looked at me and asked me why I wasn’t taking notes. I told him it’s because I remember everything about the meetings. That took him aback. Everyone else always took notes. I’m not saying that I literally remember everything. I don’t. I do remember most of the gist of everything. I read a lot and I pick up grammar, spelling and other linguistic aspects from that material. This allows me to spot typos and grammatical mistakes much easier than most people. You might have experienced some of my corrections. Mnemonics should be taught at a very early age. Without a basis for remembering things, how will anyone accumulate knowledge? Some years after I read his book a new book was published called “The Memory Book”. It has all of Harry’s techniques and then some. I found that book to be more difficult. Harry had an easy style of teaching. Harry used to appear on The Tonight Show with Johnny Carson every now and then. Before the show he would remember the names of all of the audience members. During the show random people were selected and Harry would name them.
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Replying to @brian_armstrong
You’re coming at this from the wrong end. A dinner of scientists and engineers will talk molecules, models, and dose. That’s how you get a pill. It’s not how you decide what “smarter” is for an adult human. Talk to people who work with actual minds: teachers, clinicians, people who’ve watched intelligence show up as judgment, not a score. Then bring the lab in. Enhancing cognition isn’t only “learn faster, solve harder problems.” Adults also get colder, more certain, less patient. You already know how to raise a number. You don’t know what you’re doing to the person. Wrong table first. Wrong premise. The premise is that intelligence is a performance spec. It isn’t only that. I can help.
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Replying to @brian_armstrong
Everyone's going to pull out their data of supplements and other compounds showing potential benefits in small groups of dementia patients and claim they help cognition and memory for normal people. It's going to be the ultimate snake oil salesmen get together
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Replying to @brian_armstrong
Lots of research in this area, as a Behavior Analyst (applied behavior analysis) ABA is the science of learning founded by people like BF Skinner, Fred Keller & later… William Heward. You’d wanna look in this discipline for methodologies and procedures.
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Replying to @brian_armstrong
Scammer hosting a dinner? Be careful not to get poisoned
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Replying to @brian_armstrong
I think it's very noble of you to help wealthy people improve their cognitive abilities
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Replying to @brian_armstrong
removal of poison from our food, water, and medication would be a good start~ 🙃
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Replying to @brian_armstrong
The best path for adults I'm currently aware of is editing placentally derived stem cells that colonize the brain then injecting them into the bloodstream to colonize the brain. For that purpose you'd probably want Nakoa Po from Sundial Therapeutics plus one of the gene editing companies like Aydin Gokce of General Cybernetics that can do editing of the stem cells before injection into the blood. For embryos, you've got embryo selection working now and near-term techniques like sperm selection that could plausibly be ready for the clinic in about 3 years. After that I think the best techniques are going to be gene editing of stem cells that are then turned into gametes. For that application you'd probably want to invite Alex Pastuszak of Paterna for stem cell derived sperm and Merrick Smela of Ovelle for stem cell derived eggs along with one of the companies doing multiplex gene editing in stem cells.
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Replying to @brian_armstrong
You should connect with the Gab Lab at MIT. Considering inviting John Gabrieli gablab.mit.edu
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Replying to @brian_armstrong
Safely increasing Human intelligence? I suggest you start with defining Human!
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Replying to @brian_armstrong
Have you thought of inviting the psychological side? For example Jordon Peterson or Navy Seal Jocko Willink
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Replying to @brian_armstrong
Regardless of this dinner, Boston needs a community around this concept
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Replying to @brian_armstrong
Ask naturopathic doctors to attend too!They have tools such as botanical medicine, acupuncture, gut brain axis modalities, and a different way of thinking!!
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Asking for a friend, (might nudge them to apply), would you be interested in bio PhDs who studied neurodegenerative diseases (ie Parkinson’s) at a leading lab but now focus more on bringing products and innovations to market for major hospital systems?
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Our best bet if semi possible is likely just embryo selection , increasing adult human intelligence likely isn’t structurally possible without maybe BCIs?
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Replying to @brian_armstrong
I would love to be there. I think I have a lot of important ideas about the nature of AI, consciousness, and reality to contribute.
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Replying to @brian_armstrong
My sister works with ALS patients at Mass General. Fabulous program but they need some better solutions for the disease.
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Replying to @brian_armstrong
there's lots of way to increase cognition besides the standard spaced repetition learning and other learning techniques. For nutrition, the naturopaths and functional medicine doctors know lots about using nutrition for that purpose.
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Replying to @brian_armstrong
lol bro we are stuffed full of frito-lay and artificial light at least 12 hours a day by age 6. School vending machines literally sell junk laced with neurotoxins. Let’s start there…
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Replying to @brian_armstrong
Can we just go to a Red Sox game?
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Replying to @brian_armstrong
The technology for this isn’t there yet. Look toward advancing biotech and neuroscience to develop the ground for cognitive improvement. Hope whatever comes from this meeting succeeds. We desperately need to raise the IQ floor.
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Replying to @brian_armstrong
@ced_zhang should join!
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Replying to @brian_armstrong
Can I bring my magic carpet?
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Replying to @brian_armstrong
submitted
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Replying to @brian_armstrong
Autism could use your help, not the silicone valley autism, the kind that is debilitating.
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Replying to @brian_armstrong
Our current education system is cognitively impairing our abilities. You need to fix that!
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Replying to @brian_armstrong
slip in adderrall microdoses, get instafunded @inversebrah
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Replying to @brian_armstrong
Not my expertise but just Hoping this isn’t due to the decline of close family or a friend
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Replying to @brian_armstrong
Can I apply to just be a “good vibes” guy in the room.
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Replying to @brian_armstrong
Does “scientist” include practitioners who treat individuals with cognitive impairments?
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