Proud to present our newest paper in CELL STEM CELL: Leukemic stem cell subtypes determine venetoclax resistance and therapeutic vulnerabilities in AML! cell.com/cell-stem-cell/full…

New publication from the labs of Duncan Odom, Marieke Essers, Thomas Höfer and myself @DKFZ @hi_stem_lab Concentrating cell-type-specific transcriptional signatures in bone marrow from interspecies comparisons: Cell Genomics cell.com/cell-genomics/fullt…

Welcome Chiara, we are very much looking forward working with you!

We welcome @ChiaraFalcomata, who started her new position as junior research group leader at DKFZ today. Her research focuses on how pancreatic cancer evades the immune system and adapts to therapy, with the aim of restoring anti-tumor immunity and improving treatment responses.

We will soon be hiring postdocs, engineers and researchers (on site in Heidelberg, DE) in: - Biomedical AI (multimodal foundation models, biomarkers, agents) - Robotics (lab automation, physical action surfaces for agents) - AI social sciences (multi-agent systems, agent "civilizations") - Deploying AI in a large hospital system More info at imai-heidelberg.de and kather.ai If you are interested in learning more, reach out to office@kather.ai

🚨 Amazing news from @CancerGrand @CR_UK! Two new cancer grand challenges in UPPER GI CANCERS! cancergrandchallenges.org/ap… cancergrandchallenges.org/ap… Up to $34 million in awards for global teams! Apply now and spread the word. @CharlesSwanton

Every so often, a major event happens in your life to validate years of work. SRRK’s ISEMBYLD was FDA approved. Having participated in its development from basic science to approval, as a physician-scientist, this is one of my best days. Happy for ISEMBYLD to help SMA patients.

Pancreatic tumors are highly heterogeneous and immunosuppressive. But is immune resistance imposed across the whole tumor - or built locally by distinct cancer-cell states? I’m incredibly excited to share our new paper, now out in @Nature! 🎉 doi.org/10.1038/s41586-026-1… (1/7)

Forschende von @DKFZ und @hi_stem_lab zeigten in #Mäusen🐭 und #Organoiden, wie aggressive Darmtumoren die Immunabwehr bremsen: WNT senkt CCL20. Das könnte WNT-Hemmung mit Immuntherapien verbinden. 🔗dkfz.de/aktuelles/pressemitt… #Tierversuch #Krebs

New in @NEJM: Phase 1/2 data for our RAS(ON) multi-selective inhibitor being investigated in patients with previously treated advanced RAS mutant non-small cell lung cancer. Learn more: revmed.com/media/news/13406/…

Three DKFZ-researchers have each been awarded a @ERC_Research Starting Grant this year. Daniel Kirschenbaum, Lena Kutscher & Michael Scherer impressed the ERC with their innovative research approaches to fundamental questions in cancer medicine. 👏 #ERCStG t1p.de/tk12d

The updated website is up! Don't miss the event of 2027 in the Heme Malignancies space, our 2nd @Fusion_Conf in Mexico. Co-organized with @AkEisfeld and @sanamloghavi A fantastic line up of speakers headed by @rosslevinemd and Elaine Mardis. fusion-conferences.com/confe…

It is a pity that at the fag end I was not allowed by my own institute to fly to Frankfurt despite my own travel funding & confirmed flights, what a shame!

Thank you so much, I am deeply honored!

“Dogma is a moving target” 30 years of failed anti-RAS strategies taught the field to stop accepting “undraggable” as settled. Fantastic seminar today from Dr. Mallika Singh from RVMD @DKFZ @hi_stem_lab #RAS #PancreaticCancer

Pride of place on my notice board. Hope my trainees find their first @ISEHSociety annual meeting as memorable and impactful as I did (nearly 20 years ago!!!!). #ISEH2026 #ISEH2007

Wonderful Young Investigator Lecture at #ISEH2026 by our friend and collaborator, Nina @Nina_CabezasW from @ETH_en!! @ISEHSociety

Check out our latest review published in @ISEHSociety cGAS–STING Signaling in Acute Myeloid Leukemia: Biology, Pathophysiology, and Therapeutic Implications - Experimental Hematology exphem.org/article/S0301-472…

The US FDA have now approved this drug for use against a cancer previously thought to be "undruggable" go.nature.com/3SF5HYD

🚀 You might have heard about efforts to manufacture organs in #space. But what about #medicine? 💊 Learn about pioneers in the field — including our Catriona Jamieson, MD, PhD — & their work in this @ScienceMagazine piece: bit.ly/4zH5y7t @UCSDMedSchool @thejamiesonlab