Studying how autoantibodies drive neurological disease. Autoantibodies • Neuroimmunology

New Haven, CT
A recent YSM study published in @CellCellPress links #LongCOVID symptoms in some patients to specific autoantibodies, suggesting #autoimmunity as one cause of post-infection illness. First author @keylas3 and senior author @VirusesImmunity share how their findings could lead to new diagnostic tools and #treatment options. Learn more: bit.ly/4u00lDJ
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New talks from this year's International #MECFS Conference are online! 📌 "Autoantibodies analysis in Long COVID and ME/CFS" - @keylas3​ 📌 "Effects of Autoantibodies on Neuronal Function" - Marlen Alisch 📌 "Bio-SEG PEM study" - @chris_puta​ 🔗 t.ly/of9LS
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I'm excited to share that our recent paper has been featured in Nature Reviews Neurology. Our study provides evidence that autoantibodies can play a causal role in the neurological manifestations of #LongCOVID. nature.com/articles/s41582-0… #Autoimmunity #Neuroimmunology #Immunology
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I’m honored to be featured in a Yale News article discussing our work showing that autoantibodies from #LongCOVID patients can induce neurological phenotypes in mice, providing evidence for a causal role in disease. Read: news.yale.edu/2026/05/28/y... #Autoimmunity #Neuroimmunology
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Excited to share our study in Cell! Using passive transfer experiments, we found that autoantibodies from Long COVID patients can induce neurological and pain-related phenotypes in mice, supporting a causal role in disease. cell.com/cell/abstract/S0092… #LongCOVID #Autoimmunity
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keyla sá retweeted
Important #LongCovid finding of auto-antibodies in patients directed to neural tissue, and then, by transferring the antibodies, recapitulated the disease symptoms in mice @CellCellPress @VirusesImmunity @putrinolab cell.com/cell/abstract/S0092…
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Excited to share our study by @keylas3 et al. on pathological autoantibodies in people with Long COVID. We asked whether IgG in patients with Long COVID bind to human tissues/antigens and cause pathologies when transferred into mice. With @PutrinoLab doi.org/10.1016/j.cell.2026.…
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keyla sá retweeted
Excited to have this amazing new #longcovid work out in the world thanks to an always amazing team and with continued gratitude for our collaboration with @VirusesImmunity 👯‍♀️ Please check out Akiko’s comprehensive tweetorial on the preprint, and I’ll add just a few comments. 1/
Sharing our new study by @keylas3, @SilvaJ_C, Rafael Bayarri Olmos et al (with T. Horvath & @PutrinoLab) showing that a passive transfer of IgG from patients with #longCOVID into mice recapitulates ⬆️ pain and other symptoms 🧵 (1/) medrxiv.org/content/10.1101/…
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From a @PlzSolveCFS presentation, @PutrinoLab discusses an unpublished finding from @keylas3 and @VirusesImmunity: mice some exhibit balance and sensory issues (sounds like POTS and SFN?) after being injected with IgG from human Long Covid patients piped.video/F3Sv9tfu_ww?si=PmDt…
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Essa pergunta embora pareça simples e fácil de responder ao aluno com um conjunto de “dedique-se, passe nas matérias, aprenda inglês, faça IC”; não é simples assim. Há inúmeras pedras no caminho que podem facilmente impedir o sucesso de pessoas capazes. cienciaquenosfazemos.org/pos…
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Brasileiro é swingueiro, é coração A gente é que bota fé na vida pode crê Tamo ai para viver para encarar. Se você quiser colar com a gente, não tem nada, não. 🇧🇷 o povo de mistura, é raça, é pé no chão. Objetividade na vontade de crescer. @HHMINEWS @hernandezmsilva #FHScholars
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Rare cases of #myocarditis post-#COVID19 vaccine caused by generalized immune response – not #antibodies created by the #vaccine, researchers incl. @lucasite_lab,@VirusesImmunity and @InciYildirim11 say in @SciImmunology. @YalePediatrics @YaleEMD @YaleIBIO bit.ly/420uuWt
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microshades: An R Package for Improving Color Accessibility and Organization of Microbiome Data #Microbiome #Rstats #metagenomics journals.asm.org/doi/10.1128…
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Muito legal a reportagem do Andre Julião (Agência FAPESP) sobre nosso artigo recentemente publicado na Nature Commun. nature.com/articles/s41467-0…. O artigo demonstra que parasitos do gênero Leishmania subvertem as funções de Gasdermina-D para evitar a morte dos macrófagos.
Parasita da #leishmaniose manipula defesa do organismo para continuar se replicando, mostra estudo. Divulgada em @NatureComms por pesquisadores da @usponline, a descoberta abre caminho para novos tratamentos. agencia.fapesp.br/41156/
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Parasita da #leishmaniose manipula defesa do organismo para continuar se replicando, mostra estudo. Divulgada em @NatureComms por pesquisadores da @usponline, a descoberta abre caminho para novos tratamentos. agencia.fapesp.br/41156/
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keyla sá retweeted
When we and others including PJ Utz's group saw autoantibodies skyrocket with SARS-CoV-2 infection, it raised alarm bells for exactly this possibility. It will be important to see what the hazard ratios look like post vax/prior infection. "Unfortunate legacy" indeed.
Beyond autoimmunity as a mechanism for #LongCovid, the heightened risk of autoimmune diseases "Compelling and reliable evidence that #SARSCoV2 infection is linked to a substantially increased risk of developing diverse new-onset autoimmune diseases..." nature.com/articles/s41584-0…
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