Cardiac Electrophysiologist• Professor• Board of Trustees HRS • #UCLA • #WomeninEP #EPeeps • #DigitalHealth •Tweets≠med advice 🏃🏻‍♀️🏕🏂☕️🐶🇹🇭

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✨PUBLISHED✨ Our scientific statement State of the Art of #ArtificialIntelligence in Clinical #Electrophysiology in 2025 We hope this new checklist helps both researchers & readers alike! Thank you @EmmaSvennberg & @DavidDuncker for the opportunity to contribute 🙏🏼 #EHRA2025
State of the art of #ArtificiaIIntelligence in clinical electrophysiology in 2025. A scientific statement of #EHRA_ESC, the Heart Rhythm Society (HRS), and the ESC Working Group in e-Cardiology academic.oup.com/europace/ad… @DavidDuncker @netta_doc #Europace
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Day one at #HRX2026 @experienceHRX is in the books! Looking forward to the next two days of this intentionally unconventional conference. Be there! #EPeeps
That's a wrap on Day 1 of HRX Live 2026! The Innovation Summit, our first Main Tent speaker, the opening pitch competition presentations — and we're just getting started. Stay tuned! More #HRX2026 coverage is coming your way, #EPeeps. @MehakDhande @OliverMonfredi @Nashwa_Salem_
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JK Han MD retweeted
Join the AP shark tank on main stage 1 #HRX2026 starting now Judges @netta_doc geraldine Lee & moderators @J_Hendriks1 Brynn Dechret #HRX 2026
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#HRX2026 AP sharktank is underway! Can we use AI to assit in MRI non conditional devices to MRI?
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JK Han MD retweeted
Very important message from our group. In patients with recurrent AF after a first ablation, what we do next matters. Repeat catheter ablation was associated with a 35% lower risk of death, stroke, or HF hospitalization compared with cardioversion, with an NNT of only 14. This challenges the idea that management of recurrent AF should simply be based on operator preference. Recurrence after ablation should not be viewed as failure—it may be an opportunity to intervene again and improve meaningful clinical outcomes. Congratulations to @mabou_khalil @HanFengGHD @QMarashly and the entire team. #AFib #Ablation #EPeeps @PrashSanders @shivkumarmd @gautamsand @S_NarayanMD @Phiso_de @drsuneet @drjohnm @drluissaenz @leftbundle @KennethEllenbo1 @DrBradleyKnight @DrRoderickTung @atulverma_md
AF recurs in up to 50% post-ablation, what's next is often just operator preference. Our study in Europace of 3,100+ patients: redo ablation cut death/stroke/HF by 35% vs. cardioversion (NNT=14). 🫀⚡ @nmarrouche @HanFengGHD @QMarashly 📄 doi.org/10.1093/europace/eua… #AFib #EPeeps
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JK Han MD retweeted
Replying to @TinaBaykaner
Bring your team to #WAFIB2027 for live cases, interactive debate, & practical insights spanning ablation, stroke prevention, PFA, LAAO, imaging, AI, & more. $100 Off with Code AWARENESS: hubs.ly/Q04w-2ss0 @nmarrouche @EPLabDigest
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JK Han MD retweeted
Important PVI-SHAM-AF trial—but interpretation matters. This was not ablation vs “nothing.” The sham arm included deep sedation, an invasive cath-lab procedure, intensive follow-up and, importantly, cardioversion when patients were in AF—itself an effective rhythm-control intervention. Yet ablation still produced substantially better rhythm control (73% vs 52% freedom from AF). With QoL assessed at only 6 months, are we measuring the effect of ablation—or comparing two active rhythm-control strategies? I would be cautious concluding that ablation does not improve symptoms. The study may instead demonstrate how difficult it is to design a truly inert sham for AF. #AFib #CatheterAblation #RhythmControl #PVI #ESCCongress @PrashSanders @drjohnm @chris_sohns @peterkistler3 @DJ_Lakkireddy @DrRoderickTung @TinaBaykaner @DrJasonAndrade @SteffelJ @netta_doc @TulaneHeart
One of the #ESCCongress highlights: #HOTLINE #LBCT PVI-SHAM-AF 🫀262 patients (~1/2 women! 👏🏽)with symptomatic AF → ablation vs sham 🫀At 6 mo, AF-related QoL improved in BOTH groups, with no significant benefit from ablation (P=.36) 🫀But ablation improved freedom from AF: 73% vs 52%. Better rhythm control ≠ necessarily better QoL @RoWachter I love the sham trials! Lancet: doi.org/10.1016/S0140-6736(2…
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JK Han MD retweeted
How low should we go with BP in atrial fibrillation? Our #ESC2026 study, simultaneously published in @EuropaceEiC , suggests a “sweet spot”: 🔹 SBP ~120–130 mmHg 🔹 Avoid DBP <75–80 mmHg 🔹 Lower is not always better In AF, both numbers matter. bit.ly/4yeNyQB #AtrialFibrillation #Hypertension @ElnazShmohamadi @melissaemm1 @Elliott_AD @JonathanAriya
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ENRICH-AF trial: In AF patients with prior ICH, edoxaban did not lower stroke or systemic embolism but increased major bleeding compared to non-anticoagulant therapy. Download slides here: clinicaltrialresults.org/wp-…
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EPIDAURUS trial: In patients with AF and ACS, dual antithrombotic therapy with DOAC and intensified P2Y12-inhibition with prasugrel or ticagrelor for 1 month was associated with a higher bleeding risk without reducing ischemic events compared to triple antithrombotic therapy. Download slides here: clinicaltrialresults.org/wp-…
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New consensus in #Europace 📢 Diagnosis and Management of Very Rare Primary Arrhythmia Syndromes in Children and Adults 🧩💔 @JacobTfelt @amazzanti79 @arbelo_e @GiulioConteMD @BehrElijah @CrottiLia @J_Hendriks1 @ArthurWilde5 @MJAckermanMDPhD 🔗doi.org/10.1093/europace/eua…
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📣 NEW CONSENSUS DOCUMENT Just published on #Europace Workup and management of rhythm disorders in myocarditis and inflammatory cardiomyopathy ⚡️ 🔗 doi.org/10.1093/europace/eua… @EHRAPresident @HFA_President @HRSonline @APHRSOfficial @LAHRSonline1 @GiovanniPeretto #ESCCongress
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📢 New in #Europace | #ESCCongress In 476,750 AF patients: 🔹 Lowest mortality around SBP 134 / DBP 83 mmHg 🔹 Stroke and ICH increased with higher SBP Pragmatic target: SBP 120–130, avoid DBP <75–80 mmHg 📊 🔗 doi.org/10.1093/europace/eua… @PrashSanders @ElnazShmohamadi
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#CMRGUIDE at #ESCCongress Should myocardial SCAR—not just EF—help determine who gets a primary-prevention ICD? Patients with: ➡️ LVEF 36–50% ➡️ Ischemic or nonischemic cardiomyopathy ➡️ Scar/fibrosis on CMR Randomized 353 pt, impacted by COVID, 82% Men ⏱️6.3 y ICD vs implantable loop recorder Primary Endpoint= SCD or hemodynamically significant ventricular arrhythmia 🌟RESULTS: Primary: SCD or hemodynamically significant ventricular arrhythmia ➡️ HR 0.76 (95% CI 0.37–1.58), P=.47 ❌ Sudden cardiac death alone: ➡️ HR 0.26 (0.07–0.95), P=.04 All-cause mortality: ➡️ HR 0.91 (0.49–1.71), P=.78 🫀 CMR-guided ICD implantation did not reduce the primary composite endpoint. The reduction in SCD is intriguing, but as a secondary endpoint in a negative trial it should be interpreted cautiously. CMR scar alone does not yet appear sufficient to expand ICD indications beyond current EF-based criteria. 📄 jamanetwork.com/journals/jam… @JAMA_current #WhyCMR #CardioTwitter #EPeeps #HeartFailure
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Fun session to start off #ESCCongress2026! An honor to join amazing friends from around the world for “#Artificialintelligence in #AFib care: smarter detection, safer treatment, better outcomes?” chaired by Drs. @g_andre_ng & Isabel Deisenhofer Thanks @escardio for the invite!
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JK Han MD retweeted
Presented at #ESCCongress: In patients with atrial fibrillation and intermediate stroke risk, direct oral anticoagulation led to a lower risk of stroke, systemic embolism, major bleeding, or death from cardiovascular causes than no anticoagulation. Full SINGLE-AF trial results: nej.md/4ii61XB Editorial: Anticoagulation for Atrial Fibrillation with a Single Risk Factor for Stroke nej.md/45FR7D4 @escardio
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JK Han MD retweeted
This is an incredibly important study. The just presented SINGLE-AF trial randomised patients with a single risk factor (other than sex), demonstrating a significant reduction in stroke, systemic embolism, major bleeding, or death from cardiovascular causes at 24 months. Although the @SCC_CCS AF guidelines (onlinecjc.ca/article/S0828-2…) have advocated for OAC for this group of patients for many years, sometimes at contrast with other national societies, its nice to see that this approach has been validated in a large RCT. nejm.org/doi/full/10.1056/NE…
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JK Han MD retweeted
This an important piece of data by our team further stressing the need for better risk stratification models (? Personalized models) in the era of #AI. @SteffelJ @netta_doc @AndreaRussoEP @drjohnm @EricTopol @Ed_Gerst @CMichaelGibson @PrashSanders @SanaAlkhatib9 @Drdevignair @DrMarthaGulati @TulaneTriad
A study of 900,000+ patients with AF found that female sex is not a uniform independent stroke risk factor. Higher risk emerged mainly in women aged 75+ with additional cardiovascular risk factors, reinforcing the need for individualized risk assessment. jacc.org/doi/10.1016/j.jacad…
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JK Han MD retweeted
Twenty years ago, we started the Western AF with one goal: to bring together the brightest minds in electrophysiology to improve the lives of patients with #AFib. I’m incredibly grateful to our faculty, attendees, industry partners, & the team who have made this meeting what it is today. I look forward to celebrating this milestone with all of you in Salt Lake! @drjohnm @PrashSanders @S_NarayanMD @DJ_Lakkireddy @TinaBaykaner @DrJasonAndrade @LuigiDiBiaseMD @Phiso_de @HRSonline @AndreaRussoEP @netta_doc @HanFengGHD @chris_sohns @lamcardio @DrBradleyKnight @ArashArya_EP @JamilFrancisMD @DrRoderickTung @leftbundle @OmarKreidieh1
Join us for the 20th Annual Western AFib! Feb. 25–27, 2027 | Salt Lake City ⚡ Live cases 🗣️ Expert debate 🫀 Practical AFib education 🚀 PFA, LAAO, AI, imaging & more 🔗 hmpglobalevents.com/wafib?ut… @nmarrouche
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JK Han MD retweeted
Tell me you don’t regularly take care of patients without saying a word. Clearly this question writer spends more time w a keyboard than a stethoscope 👇🏻 A) what do you use for sedation w/ those hemodynamics and b) how many seconds will this pt stay in SR? H/t @jasonryanmd
Replying to @jasonryanmd
just had an ABIM question about this, shame answer
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I don’t think any woman goes through their training not wanting to work. Over 50% of those who responded did a fellowship. There is a problem with our health system that needs to be resolved to keep the women and men we train in medicine. Including reducing the stress of the job, often due to mistreatment, discrimination & lack of opportunities for leadership roles, in addition to inequity in pay that has long been established.
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