From DNA to the brain. Occasionaly fatherhood, cycling, indie rock. No, Dad will not turn his music down.
La Jolla, CA
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I'm pleased to share our latest preprint: Combinatorial effects of gene dosage, polygenic background and environment on complex traits 🧵medrxiv.org/content/10.64898…
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Jonathan Sebat retweeted
Honky Chonk Beardonkadonk
ALT A large bear sitting in water fishing for salmon.
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Q: What 2000’s indie rock band predicted the rise of AI coding agents
A: “OK Go” okgo.net/
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This is great news. What a relief. Judy is an awesome scientist and a great leader. NHGRI is in good hands.
NEWS: NIH selects Dr. Judy Cho as director of the National Human Genome Research Institute.
Read the full story ➡️ bit.ly/3U4Jsvr
ALT Announcing Dr. Judy Cho as NHGRI Director
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i’ve seen a lot of people asking why i attacked this guy. i’d like to apologize… to absolutely nobody. Fuck him.
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Jonathan Sebat retweeted
23andMe is hiring for 2 amazing roles!
- Scientist, ML for Health Risk Prediction: build next-gen health prediction tools integrating genetics.
- Scientist, Population Genetics: build state-of-the-art algorithms for genetic relationship & ancestry inference.
Links below!
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medrxiv.org/content/10.64898… Check our new @medrxivpreprint on #ASXL3 showing the ASXL neurodevelopmental syndromes may be ASO treatable. With @n_lorem. @arrefoundation @LighthouseLeo @SimonsFdn @CIRMnews
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If FIFA's World Cup halftime show proved anything, it’s how disconnected the gatekeepers of entertainment are from common people
pitchfork.com/story/the-worl…
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@n_lorem develops two separate antisense oligonucleotide targeting toxic @SCN2A mutations to achieve meaningful improved lives in #epilepsy. at @RadyGenomics @RushMedical. nature.com/articles/s41591-0…. @EpilepsyFdn @LGS_Foundation.
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What were the odds on Polymarket that the Muppets would play 7 Nation Army in the #worldcup final?
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This year I fielded alot of questions on the causes of autism. It's good to see that some of it is cutting through the noise.
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The Tartan Army marching through South Beach. The World Cup this year has been the most cathartic single event in uniting the world.
I get it. It’s soccer. But you don’t really have to appreciate the sport to appreciate the impact. Our nation is healing and other countries are helping. I love it. ❤️🇺🇸🏴🔥
Brendan Gutenschwager
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New [Souaiaia et al. 2026 Nature] paper argues that there is "distinct genetic architecture in the tails of complex traits". Some of my thoughts:
I'm not a fan of framing traits as having distinct architectures at the extremes when it's not really what's going on
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