On March 17th, @PBS will be airing historian Niall Ferguson's (@nfergus) new miniseries "Networld". I'll be making an appearance in Episode 3 and will talk about how ISIS and Islamophobes leverage the power of networks to promote hate & violence. TRAILER: pbs.org/show/niall-fergusons…

One of the most compelling parts about working at an ElonCo was the agility to pivot to whatever the most important problem was. One day I said: I wasn’t hired to go after spam, but a tsunami is coming and I’m going to drop everything to focus on that. The org is so flat and agile that your title is basically meaningless. Anyone can sound the alarm about a problem and solve it themselves—or rally the team to join them. This is how startups work but it’s very hard to make it work in a larger company.

The limit on software used to be engineering and now it's mostly imagination. I'd spend a lot more time on the version of my idea that makes people say "wait, what is that?" Most software looks the same, so anything that looks different gets noticed, shared and remembered.

How the highest performers sustain a massive workload:

Deeply disturbed by the vile threats sent to Muslim schools across Canada. Threatening children and schools with violence is abhorrent. Every child deserves to learn in safety, and every family deserves to practise their faith without fear. (1/2) cbc.ca/news/politics/cbc-ca-…

A father has posted a video of his daughter enjoying a cardboard swing he made for her in their displacement shelter in Gaza. He described it as a ‘small moment of happiness’ amid the suffering.

Dear @marvel @marvelstudios: Please, for the love of it all, give us a one-shot of Michael Pena as Luis doing a recap of the entire MCU saga leading up to @Avengers: Doomsday.

Houston Texans linebacker Azeez Al-Shaair was told by an NFL official to remove the name of Wafaa Akila, an 8-year-old Palestinian girl killed in Gaza, from his eye black during the Texans’ Week 2 game or he would not be allowed to continue playing, according to a league source. According to Reuters, Wafaa Akila was killed earlier this month by an Israeli airstrike. nyti.ms/4yWHU5I

The Netanyahu campaign to extinguish the possibility of a future Palestinian state by building Israeli settlements in the E1 area of the West Bank must end. I'm leading a new effort to sanction those involved in its development and preserve a future pathway for peace. jewishinsider.com/2026/09/co…

NEWS: We're bringing @AJHeadtoHead, my live-audience interview show for Jazeera to Washington DC, to Georgetown, on Oct 6th for a midterms special - my first guest is @neeratanden. We'll talk Dems, the left, DSA, & more. For free tickets, register here: docs.google.com/forms/d/e/1F…

It's a benchmark that shows how many times each AI Lab's models have "escaped" and hacked another company, committing a felony. Here's the website: felonybench.com/

Last night I planted an olive tree at Gracie Mansion with Palestinian families from Gaza.  May peace be our future.

Today we announced the Claude-led discovery of a molecular machine that we suspect could represent a new gene editing mechanism. Its precise function, biotechnological utility (if any), or level of significance is not yet clear, but at minimum it is work I would have been proud to do as a PhD student. The work was done mostly, though not entirely, by Claude: our life sciences team suggested a broad area of research, Claude read through the literature and a bunch of genome data and discovered something interesting, then Claude proposed experiments to verify the discovery and our team carried them out. It’s easy to dismiss this as a one-off or curiosity, but we’ve repeatedly seen a pattern where AI performance in new intellectual domains goes from weak to superhuman in a matter of a few years. In 2023 models struggled to do math at the level of an average high-school student. In 2024 they started to do well on math competitions for the best high-schoolers in the country, in 2025 they started to solve minor open problems, in early 2026 more significant open problems, and in late 2026 they are beginning to solve the top few open problems in all of mathematics. We believe AI for biology is on a similar exponential trend. The main difference between biology and mathematics, of course, is that math can be done purely theoretically, while biology requires experimentation. Some have used this to draw the conclusion that AI’s utility in biology will be limited. We think this is wrong. As we’ve demonstrated today, humans can collaborate with AI to perform the experiments, validate key results in a few weeks and, if necessary, work with the AI to iterate on what they find. Eventually it may even be possible for Claude itself to safely perform the experiments by autonomously controlling lab equipment, with appropriate safeguards in place, but we aren’t doing that today (our lab is also a BSL1/BSL2 facility that doesn't handle materials dangerous to humans). More broadly, biomedical advancement has many stages — from fundamental biology discoveries, to translational research, to drug discovery, clinical trials, and finally the actual delivery of medicines and health care to patients. We are also interested in these later stages, but even simply accelerating the first stage of fundamental biological discoveries has the potential to speed up and broaden the entire pipeline. Improving our understanding of biology and sharpening biologists’ tools can drive forward all of the later stages, for example by identifying new drug targets, finding new therapeutic modalities, allowing for more precise measurement, and speeding up the experimental loop which itself further accelerates our understanding of biology. This will not in itself speed up clinical trial times, but if it succeeds it could greatly increase the number of promising candidates that go into the pipeline — an increase in throughput even though latency remains. In Machines of Loving Grace, I wrote about AI’s potential to “cure most diseases in 5-10 years” — a goal that sounds impossible, but one I believe is just barely possible if AI is applied to every stage of the pipeline. The first step is showing that AI can first help with, and then drive, biological discoveries. Claude’s discovery is the latest in a line of related prior work that goes back decades, beginning with systems like CRISPR, and continuing with discoveries like the bridge recombinase and VIPR in the past few years. Recently, there has been heightened interest in systems based on reverse transcriptase (RT) enzymes, the enzyme underlying the system Claude identified. And most recently, a Stanford team working independently described a novel RT system with an associated non-coding array that is in some ways similar to the one Claude found, though they are distinct systems that evolved independently from each other. I believe that we’re at the very beginning of finding such systems and developing them into powerful tools for biotechnology. I’m proud of the resources Anthropic has invested in accelerating the public benefits of AI through the life sciences, and we’re aiming both to grow our life sciences team and to work with other scientists to extend this approach to a broad range of problems. If you have a proposal for a research collaboration or are interested in joining our life sciences team, please reach out.

The more I use AI for product development, the more I'm starting to realize that most of the debate about this technology is happening amongst folks who aren't using it to build. Once you spend any amount of time with it, I don't understand how you can feasibly conclude that we aren't standing at the precipice of one of the biggest stepwise functions in the history of software products. I'm not saying that AI can turn some hobbyist into a world-class software engineer, but the productivity and speed gains are truly unbelievable. If you find yourself struggling to pick a side in this ongoing discussion, my suggestion would be to go chase an idea and build something. I'm guessing you'll be totally flabbergasted.

For over a decade, The Bridge Initiative has tracked, exposed, and equipped others to fight Islamophobia through rigorous research. As the problem intensifies, our work remains vital. Support our work: shorturl.at/Wl2zW

Scrum made sense at companies/teams that shipped a new version of their product every 2-3 months (or less frequent) As soon as a team got to shipping daily or had CD: they only held teams back Most startups + Big Tech moved on a decade+ ago, legacy companies remained only

Using Jev to catch Codex workers ignoring AGENTS.md. Combine live Codex output, Git changes, and AGENTS.md into one observation Use Jev to score the probability that the worker is drifting from AGENTS.md Steer the active Codex turn when drift crosses a threshold, stopping it if the drift continues Added to Foreman, which automatically watches and steers workers on the software factory floor. github.com/thruwire/foreman

Neera, as a Precinct Delegate in Oakland County, Michigan I am part of a team of 150 responsible for educating and motivating voters. We knock on lots of doors. Do you know how many times Piker’s name has come up? Zero

Ted Cruz was born in Calgary, Canada and has never had his citizenship questioned. Abdul El-Sayed was born in Detroit and Marco Rubio said he will be “investigating his immigration status.” Marco Rubio has BIRTHRIGHT CITIZENSHIP. The hypocrisy is actually quite staggering.

Bo French is a racist but so are most of the Republicans statewide candidates. Abbott, Patrick, Huffines and Mayes have used Muslims as a punching bag. None of the statewides have asked French to resign or delete his posts. Why is that? It is because a large portion of their supporters are comfortable with his racism. Nothing is said about the brutal mass deportations of Hispanics who have no criminal record.

I’m not particularly attached to the term “South Asian.” I understand the frustration some people have with using it as a catch-all, especially when the specific target of an incident is clearly identifiable. But right now, whether people want to admit it or not, this is increasingly bigger than any one South Asian community. South Asians as a whole are being caught in a broader current of racialized hostility, and trying desperately to distinguish ourselves from one another is not going to protect us from people whose hostility is fundamentally based on race, ancestry, and perceived foreignness. We can spend all day explaining that Indians aren’t Pakistanis, Hindus aren’t Muslims, Sikhs aren’t Hindus, Gujaratis aren’t Punjabis, or arguing that some groups are more assimilated than others. Those distinctions may matter enormously to us culturally, religiously, and politically. But they mean absolutely nothing to someone whose fundamental objection is that there are too many brown people in America.