The Center for Translational and Experimental Cardiology (CTEC) is a research hub within the Zurich University Heart Center @unispital_USZ @uzh_ch

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CTEC - Zurich University Heart Center retweeted
Excited to share our new review in @CellCellPress. We propose fibrosis is a reversible state encoded in chromatin circuits shaped by immune-stromal crosstalk, and that rewiring this logic may offer durable therapeutic paths. @GladstoneInst authors.elsevier.com/sd/arti…
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CTEC - Zurich University Heart Center retweeted
🚨1/ New in @ESC_Journals European Heart Journal: Micro & nanoplastics (MNPs) are detectable in the human coronary circulation and are higher in acute MI. 🔥2/ In patients undergoing coronary angiography, MNPs were found in 84.2% of STEMI vs 40% of chronic coronary syndromes & 31.8% of controls (P=.002), with higher concentrations & greater polymer diversity in STEMI. Polyethylene predominated (97%). 🔥3/ MNP detection co-occurred with ↑IL-6 & TNF-α, greater chronic PM2.5 exposure & smoking. Smoking was an independent predictor of MNP presence (OR 5.69). MNP detection independently predicted obstructive CAD. 🎯4/ A call to action to reduce exposure to MNPs, highlighting the cardiovascular exposome as an emerging frontier in cardiovascular risk. 👉Micro- and nano-plastics in the coronary circulation and air pollution exposure in ischaemic heart disease presentation academic.oup.com/eurheartj/a… #Cardiology #MicroplasticsAndHealth #AirPollution #STEMI #CardiovascularDisease #Exposome #EuropeanHeartJournal #ESC
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CTEC - Zurich University Heart Center retweeted
Our latest work is out in @CellReports! Read the press release by the @UZH_ch: news.uzh.ch/en/articles/medi…
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That's a lot of spatial human proteomics! >13,000 proteins ~3,0000 samples 58 major tissues types 25 cancer types nature.com/articles/s41586-0…
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CTEC - Zurich University Heart Center retweeted
Obesity doesn't just affect the waistline—it reshapes the brain. Emerging evidence suggests chronic metabolic overload disrupts neurovascular coupling, blood–brain barrier integrity, cerebrospinal fluid dynamics, and myelination, creating conditions that may accelerate neurodegeneration. As obesity and neurological disorders rise in parallel, understanding these interconnected pathways could reveal new strategies to protect brain health across the lifespan. #Neuroscience #Obesity #BrainHealth nature.com/articles/s42255-0…
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CTEC - Zurich University Heart Center retweeted
How does oxygen sensing shape alveolar #macrophage (AM) identity? In our new @CellReports HIF-1α and HIF-2α play distinct, non-redundant roles in AM maturation & function A #metabolic split that defines macrophage biology in the lung. OPEN: sciencedirect.com/science/ar… @CNIC_CARDIO
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CTEC - Zurich University Heart Center retweeted
Dietary (caloric) restriction has so many salutary effects for slowing the aging process in animal models, but whether that can be simulated in some way in people remains unclear. This new comprehensive review @NatureAging is outstanding nature.com/articles/s43587-0…
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Congratulations to @Lux_Telesca for being awared the prestigious Guido Tarone Award at the HF Winter Meeting 2026 in Berlin! #HFpEF #PH #obesity #CostantinoLab @FrancescoPaneni @UZH_ch @CardioZurich @Unispital_USZ
Honored and truly grateful to have received the Guido Tarone Award 🏆 for the Best Selected Abstract at the Heart Failure Association (HFA) Winter Meeting 2026 in Berlin 🇩🇪. Our work, “Fibroblast–Endothelial Crosstalk in Cardiometabolic HFpEF–PH” .
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CTEC - Zurich University Heart Center retweeted
The science of regulatory T cells (Tregs) got the @NobelPrize last year. Now a first-rate review of where they are headed in the clinical arena cell.com/cell/fulltext/S0092…
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Natural daylight and improved glucose control in Type 2 diabetes cell.com/cell-metabolism/ful… @Cell_Metabolism
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What an achievement of the @PaneniLab ! Congratulations to our Director @FrancescoPaneni and his team!
I am thrilled to announce that I received an #ERC Consolidator Grant! This marks the very first #ERC grant in the history of our Cardiology Department, and I am extremely proud of this achievement. @CTECresearch @UZH_en @CardioZurich @PaneniLab med.uzh.ch/en/news-events/de…
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CTEC - Zurich University Heart Center retweeted
🚨Our new article is now out in #JCI @jclinicalinvest! Together with #Frank_Ruschitzka and @VidalPuig, we highlight how gut #microbiota is emerging as a therapeutic target in #cardiovascular disease. #Saeedi_Lab @CTECresearch @CardioZurich @FrancescoPaneni @EricTopol @agingdoc1
The mechanistic evidence supporting gut microbial metabolites and link to cardiovascular aging @jclinicalinvest jci.org/articles/view/201468
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What a success for our Center at the #CBHF meeting in Naples! Congratulations to @LDiVenanzio and #ValeriaMasciovecchio for their awards! Celebrating great science with friends from all around the world💕
What an amazing #CBHF meeting in Naples! I do feel privileged to work with such a dream team💜 Stay tuned😊 @CTECresearch @CardioZurich @UZH_en @Unispital_USZ @escardio
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CTEC - Zurich University Heart Center retweeted
#CardiovascularDiabetology @BioMedCentral Awards Associate Editors of the Year 2025 🎉🏅 Cardiovascular Diabetology is delighted to announce the Associate Editors of the Year 2025: ✨ Prof. @DidacMauricio ✨ Prof. @FrancescoPaneni This recognition highlights their outstanding dedication, leadership, and invaluable contributions to advancing scientific progress in cardiovascular health and diabetes research 👏👏👏. communities.springernature.c…
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CTEC - Zurich University Heart Center retweeted
Two days left to submit an abstract for oral presentation or poster for the New Cardiobiology at EMBL Heidelberg. Don’t miss it. Engineering and Cardiovascular is the future! Deadline extended to Nov 17th!
‼️ Deadline extension alert ‼️ The abstract submission deadline for the EMBL Conference 'The new cardiobiology: engineering, vascular, and molecular insights' has been extended! The new deadline for #EMBLCardioBiology is 10 November 👉 s.embl.org/ncb26-01-x Cardiovascular disease research is evolving fast – from molecular mechanisms to tissue engineering and systems biology. Join us as we unite experts pushing the frontiers of heart and vascular science. 🧬 Don't miss your chance to share your work and shape the future of cardiobiology. 👉 Submit your abstract today! #EMBL #EMBLEvents #EMBLconference #cardiobiology #cardioresearch #tissueengineering #systemsbiology
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CTEC - Zurich University Heart Center retweeted
🌍 Today is World Diabetes Day 2025 - theme: “Diabetes & Well-Being” Explore how Diabetes affects health, the workplace, and everyday life in this insightful piece by @SpringerNature @BioMedCentral: communities.springernature.c… #WorldDiabetesDay #DiabetesAndWellBeing #CardiovascularDiabetology @BioMedCentral
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CTEC - Zurich University Heart Center retweeted
Amazing conference on gut microbiota as both a window and a lever for cardiovascular aging. Gut microbiota as a modifiable driver of cardiovascular aging, highlighting causal microbial pathways & metabolites & discussing strategies to therapeutically target them #FBRLectureSeries
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CTEC - Zurich University Heart Center retweeted
Special thanks to Prof. Antonio Vidal-Puig @VidalPuig and Dr. Stefania Carobbio @stefcarobbio for this kind invitation. See you all tomorrow at @CIPFciencia in beautiful #Valencia.🇪🇸🇨🇭 @CTECresearch @CardioZurich @UZH_en
📢Join us tomorrow! #FBRLectureSeries conference by Dr. Soheil Saeedi @SoheilSaeedi5 Gut Microbiota: From Biomarker to Modifiable Driver of Cardiovascular Aging. Current challenges & future prospects for translating #microbiome discoveries into actionable #cardiovascular medicine
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CTEC - Zurich University Heart Center retweeted
🎥 Here’s another episode of the #KnowTheAuthors series by #CardiovascularDiabetology @BioMedCentral aimed at highlighting the brilliant scientists behind the research. 📺In this episode, Dr. Ruijie Xie presents key insights from their study on cardiovascular risk prediction in patients with type 2 diabetes using metabolomics. 📄 Read the full article: cardiab.biomedcentral.com/ar… 📺 Watch his research summary in the video below 👇 👏 Senior author: Ben Schöttker 🏥 Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany @VHentschke @fcowester @ZviFisman @FrancescoPaneni @CTECresearch #CardiovascularResearch #DiabetesResearch
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