Investigating assembly, dynamics, and function of host-microbe systems. META Center for Host-Microbe Systems Biology Institute of Molecular Biology
University of Oregon
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- Following 36
- Followers 152
- Likes 36
GuilleminLab retweeted
Mucin-binding adhesins: A key to unlocking the door of mutualism. @Goo9Han @ShipraVaishnava highlight work of @tjarrods @GuilleminLab unveiling that mucus binding by bacteria is crucial for host-microbe symbiosis. cell.com/cell-host-microbe/f…
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GuilleminLab retweeted
Sticking point for Aeromonas. @tjarrods @GuilleminLab report #zebrafish #symbiont, Aeromonas, uses mucin-reg. adhesin to control its inflammatory character & spatial organization in gut.Analogous Akkermansia adhesins suggest similar mechanisms in human gut cell.com/cell-host-microbe/f…
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GuilleminLab retweeted
Cell-type-specific responses to the microbiota across all tissues of the larval zebrafish dlvr.it/SjPf71
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Congratulations to @SconceMichelle and her fantastic team of co-authors on the publication of this Gnotobiotic Atlas that reveals the impacts of the microbiota on transcriptional programs across all tissues of a model vertebrate, the zebrafish: sciencedirect.com/science/ar…
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GuilleminLab retweeted
We couldn't be more excited for our Gnotobiotic Atlas to be published today! sciencedirect.com/science/ar…
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GuilleminLab retweeted
Our #SpotlightZebrafish this week is on Dr. Laura Desban @DesbanLaura a #postdoc with #EisenLab & @GuilleminLab @uoregon. She studies how interactions between microbes and chemosensory systems shape animal behavior– specifically in context of olfaction and social behavior (1/2)
ALT An image of a 6 dpf larval zebrafish head immunostained for elav in magenta, SV2 in cyan and pERK in yellow.
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GuilleminLab retweeted
For bacterial genome sequencing, would you pick fast, good, or cheap? Now you can get ALL 3 with our new ONT sequencing service that almost always produces circular, full-length bacterial chromosome contigs with consensus accuracy >Q50 -- often with their full plasmids too! (1/3)
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GuilleminLab retweeted
Our paper is out today in PLOS Biology, please RT and tell us what you think! We discovered that bacteria encourage zebrafish social behavior by promoting microglial remodeling of 'social neurons'.🧵
journals.plos.org/plosbiolog…
@PLOSBiology @MooreFoundation @LSRFdtn @ZebrafishRock
ALT Symbiotic gut bacteria (yellow) promote social behavior by influencing forebrain development in zebrafish. Illustration by E. Anne Martin.
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GuilleminLab retweeted
New! Online now: BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases β cell mass dlvr.it/Sb51Ff
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So pleased to see the publication of this epic story from @Jen_Suzanne, @SconceMichelle, @emmaligh, Elena Wall, Jim Remington, @RParthasarathy7, @RoundLabUtah, @MurtaughLab
authors.elsevier.com/a/1fvea…
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GuilleminLab retweeted
So proud to finally share our finished work describing the membrane busting mechanism of our beloved bacterial BefA protein, out today in @Cell_Metabolism! authors.elsevier.com/a/1fvea…
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GuilleminLab retweeted
Two prominent research groups come to a shockingly similar finding from totally different angles! Checkout these two papers #OnlineNow
@seeleyrj #KarenGuillemin
🔗 cell.com/cell-metabolism/ful…
🔗 cell.com/cell-metabolism/ful…
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GuilleminLab retweeted
Also, check out* this Essay in @ScienceMagazine by lead author of the BefA paper, Jennifer Hampton Hill, winner of the 2022 NOSTER & Science Microbiome Prize
science.org/doi/10.1126/scie…
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GuilleminLab retweeted
Honored to be selected as the winner of this year's Noster & Science Microbiome Prize! A huge thanks to all the support on this epic project @GuilleminLab @RoundLabUtah @MurtaughLab Go read my essay on beta-cells and microbes in @ScienceMagazine ! 🤩 science.org/doi/10.1126/scie…
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GuilleminLab retweeted
Jennifer Hampton Hill is the winner of this year’s NOSTER & Science Microbiome Prize for her work showing that restoring lost bacterial cues in the gut can stimulate development of insulin producing cells.
Learn more: fcld.ly/28z28x0
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I am so proud of @Jen_Suzanne, Grand Prize Winner of the Noster & Science Prize for this essay about her pioneering work:
From bugs to β cells science.org/doi/10.1126/scie…
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This preprint describes the vast transcriptional responses elicited by the microbiota across every cell of the developing vertebrate body: biorxiv.org/content/10.1101/…
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GuilleminLab retweeted
Our work on the biochemical mechanism behind a bacterial modulator of host development is out as a preprint. Check it out to learn how both host and microbial membrane perturbing proteins promote the expansion of insulin producing beta-cells. #microbiome #BefA
A microbiota membrane disrupter disseminates to the pancreas and increases β-cell mass biorxiv.org/cgi/content/shor… #bioRxiv
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Our preprint describes how a secreted bacterial protein, BefA, disseminates through the body and stimulates pancreatic beta cell expansion via its membrane permeabilizing activity: biorxiv.org/content/10.1101/…
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