FY10 (Dr) interested in all things medical, research and education. I also throw around heavy things for fun. All views my own.
Birmingham, UK
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medicurious.substack.com/
#MediCurious is a blog I write and manage on Substack. It covers everything and anything vaguely medical with a focus on #FOAMed
Check it out &get in touch if you want to contribute.
#MedEd
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Jake Matthews retweeted
This is a big moment, and deeply troubling to many long term
members of the Greens … bbc.co.uk/news/articles/c6jd…
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The use of a surrogate endpoint in a clinical trial may allow faster approval of a novel treatment, but at the cost of increased uncertainty about treatment benefit.
This paper presents guidance for surrogate endpoint evaluation
bmj.com/content/394/bmj-2026…
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What happened to 'statins save lives'? In this 31,000 person RCT over 7 years, CVD screening put 44.33% of people on statins (compared to 30.25% in non screening) but prevented neither deaths nor CV events (HR 0.96). Funny how I don't see this trial EVER being discussed by cardiologists. One major difference with this trial compared to so many other statin trials is that it is not funded by a statin maker. academic.oup.com/eurheartj/a…
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What a treat to be invited onto @triggerpod
Hosts with inquisitive minds, honesty and a sense of humour. An antidote to a MSM which too frequently possesses none of these things.
The Warning Signs Britain Ignored - Colin Brazier
Watch the full episode with @ColinBrazierTV right here on X.
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Im a huge fan of Mr Clarkson, but on this one, he is wrong.
PSA is not a good test.
We do not have a good way to accurately find young men with aggressive prostate cancer. Except see a doctor if you have symptoms or a family history or you've smoked.
#GP #screening #PSA
Until last week, men over 50 were entitled to a free PSA prostate cancer check. But the government has now decided to withdraw that right. I cannot for the life of me work out what their reasoning might be.
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Check out my latest article: SYSK-3: Scurvy Sea Dogs, James Lind and Why we do trials linkedin.com/pulse/sysk-3-sc… via @LinkedIn
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SYSK-3: Scurvy Sea Dogs, James Lind and Why we do trials, by @JakeMat91 #SYSK #MediCurious medicurious.substack.com/p/s… @LindAlliance
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Read this @Doctors_net_uk news story: Early oral antibiotics in paediatric pneumonia - GIM Journal Watch doctors.net.uk/news/early-or…
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The inside story of the #RIFTStudy (Right Iliac Fossa pain Treatment), by @JakeMat91 medicurious.substack.com/p/t…
#RIFT #WMRC #research #FOAMed #appendicitis
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Studies You Should Know #SYSK
A new series from #MediCurious
The aim is to produce a syllabus, a cannon, a list of important studies and papers that changed medicine.
I want this list to help teach students and clinicians about #EBM and history
open.substack.com/pub/medicu…
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#SYSK no 2. How redesigning a figure (and some complicated maths) changed how we decide when to do an RCT.
Lives for #EBM students:
Equipoise
Meta analysis
The power of figures
What should we cover next?
open.substack.com/pub/medicu…
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linktr.ee/jakemat91
For all of the posts from #MediCurious and my presentations and papers...
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Delivering a National Care Service in England is easier said than done: There is already a post-code lottery in access to @NHSEngland funded care via @BenZaranko
archive.ph/YVlx2#selection-1…
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