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Results from a new study in @Dev_Cell provide evidence that species-specific regulation of proteasome-mediated proteolysis influences the timing of neural development and suggest that evolutionary tuning of proteasomal activity contributes to differences in embryonic developmental pace. Read more about the findings here📕 : bit.ly/4y8FroY

New study in @CellPressNews: research findings unveil a mechanism linking cancer metabolism with cancer neuroscience and leverage human genetics to nominate gluanidinoacetate synthesis as a target in #gliomas. Read more here: bit.ly/4yibjI1 #CancerResearch #Neuroscience

Findings from a new @NeuroCellPress study define inhibitory input as a suppressive component of the #glioma ecosystem and suggest that strengthening inhibitory tone may offer a therapeutic strategy. Read more here📕: bit.ly/4hzcD2W

🚨 New study in @CellCellPress unveils a mechanism linking #cancer metabolism with cancer neuroscience and nominates guanidinoacetate synthesis as a treatment target in #gliomas! Read the full #OpenAccess article here: bit.ly/4yibjI1 🧠

A new study reveals a hypothalamic-brainstem circuit linking acute stress to feeding suppression and gastric dysfunction. Read the paper: bit.ly/4xrbPC4 Led by first author Dan Dai and corresponding authors Jinfei Ni and Shumin Duan at @FudanUniv and Zhejiang University. #Neuroscience #StressResponse

Scientists from @Stanford define the architecture of the mouse serotonergic projectome! 🤯 They show organization by functional relatedness rather than the physical proximity of targets. Published in @CellCellPress: bit.ly/4r8ua5r

.@US_FDA approved Enigma Biomedical's TAUKLARIFY™ for use in patients being evaluated for #Alzheimers! 🧠 Press release 👉 bwnews.pr/46fATAR

Scientists from @UofCalifornia and @Princeton developed a fluorescent bifunctional reporter that can track estrogen response dynamics in #neurons!🧠 Read more here 👉 bit.ly/4gNbZgR

Researchers have defined the spatial + molecular determinants of malignant synapses by analyzing intact human #glioblastoma specimens. They revealed enrichment of synapse-like structures and synapse-associated gene programs at the tumor–brain interface. 🔬go.nature.com/4ygm50R

Yale School of Medicine (@YaleMed) has received a grant of nearly $25 million from the Aligning Research to Impact Autism to map human brain development and investigate how and when autism diverges from typical development. 📰 bit.ly/4xzlGqh

A research team at Sun Yat-sen University Cancer Center developed an intracavitary RNA-delivery hydrogel that targets tumor–neuron synapses after #glioblastoma surgery, suppressing recurrence and extending survival in preclinical models. 🔓 #OpenAccess Learn more at @natBME: ▶️ go.nature.com/4ygm50R

Researchers alongside Dr. Jeffery Twiss at @UofSC showed that a REG3A–KHSRP signaling loop within injured #axons restricts nerve regeneration through localized protein synthesis, revealing a potential target for accelerating nerve repair. 📕 @ScienceAdvances 🔖 bit.ly/4yxMLdN

Researchers from the Blanchard Lab at @IcahnMountSinai developed an #iPSC-based 3D model that integrates neurons, glia, myelin, and cerebrovascular cells into a human brain-like tissue, “miBrain”. 🧠 📘 @CellStemCell 🔖 bit.ly/4dalju3

In this @Nature publication, researchers from the Institute for Basic Science identified aberrant ERBB4 expression in excitatory neurons as an early driver of multiple #Alzheimers disease pathologies. Learn more here: 🔖 go.nature.com/3SYWJWf

Dr. Jie Zheng and colleagues from Peking University (@PKU1898) review emerging strategies to selectively target pathological tau, from gene silencing and immunotherapy to protein degradation and tau modification, for treating #neurodegenerative diseases. Learn more here: 🔖 bit.ly/4qNLCMj

In this review, researchers summarized current findings on #GABA-mediated #glial-neuronal crosstalk, with emphasis on its roles in central nervous system physiology and its multifaceted regulation in neurological and neuropsychiatric disorders. 🔗 go.nature.com/4gjJ1Gx

New in @CommsBio! 🧫 Researchers' findings suggest that daily light exposure enhances retinal #organoid differentiation, opening avenues to investigate molecular and cellular phenotypes in inherited #retinal diseases and accelerate therapy development in more relevant functional models. 👀 Learn more: go.nature.com/4xleLRz

Scientists summarize current findings on GABA-mediated glial-neuronal crosstalk, with emphasis on its roles in #CNS physiology and its multifaceted regulation in neurological and neuropsychiatric disorders. 🔖 go.nature.com/4gjJ1Gx

Scientists from the Ramachandran Lab (@KVRamachandran5) at @Columbia developed STARFISH to reveal that tau is locally produced in #neuronal dendrites, where neuroproteasomes rapidly degrade excess tau to prevent its mislocalization and aggregation. @NatureNeuro go.nature.com/3UKTPVt

This 'important' Tools and Resources paper establishes a robust live-imaging toolkit to characterize excitatory and inhibitory synaptic dynamics during neuronal development. The methodology and quantitative data are 'convincing' and well validated. elifesciences.org/articles/1…