Assistant Professor @UPMCHillmanCC | @DamonRunyon Dale Frey Scientist | microbiome & immunotherapy | follow your gut | she/her/hers | views are my own
Pittsburgh, PA
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I am thrilled to finally share my lab's first paper showing that sucralose consumption reduces immunotherapy efficacy in cancer, published NOW in @CD_AACR ! Let's break it down. 1/n
aacrjournals.org/cancerdisco…
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Overacre Lab retweeted
WTH is wrong with Russ Vought!?! Some personal vendetta against NIH and biomedical research? He is slowing scientific progress, massively undermining our global competitiveness, and because of him, we will have fewer new therapies for disease
nytimes.com/2026/09/20/scien…
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Apply and join us for a fantastic program!
Applications are now open for the SITC Sparkathon Class of 2027, focused on the next generation of cellular therapies! Connect, collaborate and grow your career. Apply today: sitcancer.org/career-develop…
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Overacre Lab retweeted
Stellar viewpoint from Ira on the current status of cancer immunotherapy - takeaway message: small biotech and academia will need to continue to keep the candle lit for immuno-oncology, and more mechanistic studies will be needed to find the next big thing nature.com/articles/s41577-0…
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Always a great time!
Thrilled to cut loose with the lab for our @OveracreLab vs @DelgoffeLab Lab Olympics 2026! Popular events include chair curling, wet glove races, pipet javelin, and a contentious parafilm stretch competition!
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Had a fantastic time at @socmucimm #ICMI2026 with @jessica_jana_ and @Kate_Wolfgang_ in Montreal! A wonderful few days of sharing our work and learning so much. Until next time!
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Announcing the 2026 #SITC election results! Thank you to all of the candidates for their interest in serving the society, and to the members who voted. sitcancer.org/get-involved/2… #immunotherapy #cancerIO
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Overacre Lab retweeted
Dearest gentle reader, we are delighted to announce a new story from our lab published in @Nature describing how a meal's systemic metabolic changes are interpreted by your immune system to enhance adaptive immunity. A thread 1/ nature.com/articles/s41586-0…
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Overacre Lab retweeted
Congratulations Dr. Finn, an amazing immunologist who continues her research on vaccines at UPMC Hillman & the University of Pittsburgh! @pitt_immunology @PittHealthSci @UPMCnews @UPMCPhysicianEd
It was an absolute honor to introduce Dr. Olja Finn as she received the AAI Distinguished Mentor Award @ImmunologyAAI this year. Olja, you are a pioneer in science, mentorship, and life. 👏💕💜 #IMMUNOLOGY2026 @UPMCHillmanCC @PittTweet
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Congratulations to Drs. Dario Vignali @Vignali_Lab and Sarah Gaffen (@PittDeptofMed, @PittRheum) on being recognized as 2026 Distinguished fellows yesterday at @ImmunologyAAI #IMMUNOLOGY2026!
ALT Sarah Gaffen and Dario Vignali holding their American Association of Immunologists (AAI) Distinguished Fellow of 2026 awards at the AAI meeting in Boston.
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Had a fantastic time at the Case CCC Microbiome Conference! Thanks for the invite @nataliesilvermd - what an inspiring event!
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A belated but very happy 4th birthday to the lab 🎉 so thankful for such an awesome crew! Here’s to many more years of science and fun.
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Overacre Lab retweeted
Diet soda could be sabotaging cancer treatment. Exercise could be boosting it. It all comes down to the gut microbiome. @PittHealthSci and @UPMCHillmanCC researchers are figuring out how to harness gut bacteria and protists to improve cancer outcomes: immunology.pitt.edu/news/tru…
ALT Illustration of a gut filled with microorganisms with a background of cancer and immune cells
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Overacre Lab retweeted
Next up in our trainee spotlight series is Katelyn Wolfgang (@Kate_Wolfgang), a graduate student in the @OveracreLab who studies how a commensal gut bacterium drives the formation of tertiary lymphoid structures in the colon: immunology.pitt.edu/news/tra…
ALT Trainee Spotlight graphic with photo of Katelyn Wolfgang, graduate student in Abby Overacre's lab.
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Overacre Lab retweeted
New paper in @NatureMicrobiol.
Spatial RNA mapping of microbiome and host. In situ polyadenylation is the key idea. More to come on this.
Thank you @NIH and @weandmecfs.
nature.com/articles/s41564-0…
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An incredible study, congrats all!
Spatial transcriptomics maps host–gut microbiome biogeography at high resolution
nature.com/articles/s41564-0…
@NatureMicrobiol @dwmckellar @ntekasi @IwijnDeVlaminck @Cornell
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Congrats to @jessica_jana_ and Kelsey Ertwine for receiving @ImmunologyAAI awards at @TRCCC1998 this year!!
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Congrats to @ItzDipyaman for being selected for a SITC sponsored talk where he talked about Tregs and irAEs!
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