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1/10 Delighted that our study using pharmacogenomics to find compounds promoting oligodendrogenesis and repair in myelin pathologies is now published in Nat Communs, after 7 years of work! rdcu.be/dZ89J (DOI: 10.1038/s41467-024-54003-9)
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9/10 These findings support the repurposing of leucovorin and dyclonine for clinical trials targeting myelin disorders, offering potential therapeutic avenues for preterm brain injury and Multiple Sclerosis
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10/10 Many thanks to all contributors from @TheHassanLab, @InstitutCerveau, our collaborators from Olivier Raineteau lab and funders (ANR NeoRepair & ANR NeoReGen, @France_SEP, BDL Capital Management)
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We invite you to become member and register for free on the website italianglianetwork.wixsite.c…, involving colleagues who may be interested in this initiative
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Carlos.Parras.Team retweeted
Our latest paper out by @merbengochea @TheHassanLab about the numerical cognitive abilities of flies and the first evidence for the neurons required for this capacity in the visual system
"Numerical discrimination in Drosophila melanogaster"
@InstitutCerveau Laurent Cohen, @bassemh1
Read more in @CellReports cell.com/cell-reports/fullte…
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Carlos.Parras.Team retweeted
Et si la maladie d’#Alzheimer imprimait sa marque chez l’embryon ? Des scientifiques de l’@InstitutCerveau (@inserm), montrent que la protéine précurseur de l’amyloïde (APP) possède un rôle biologique spécifique lors du neurodéveloppement.
institutducerveau-icm.org/fr…
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Carlos.Parras.Team retweeted
@ShabaniDania @TheHassanLab @InstitutCerveau @ParisBrainInst paper on how the APP protein-famous for its role in Alzheimer’s disease- is actually a regulator of the tempo of human cortical development is now out in @ScienceAdvances
science.org/doi/10.1126/scia…
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Carlos.Parras.Team retweeted
June 20th in Paris: 'The Times of Embryonic Development’ A symposium at Collège de France @cdf1530. Open, no registration, super speakers 👇🏼@PourquieO @DesplanLab @briscoejames @EbisuyaMiki @VanderhaeghenP2 @maitrejl @Anissakempf @gregorscience @the_Node @LecuitLab
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Carlos.Parras.Team retweeted
braincouncil.eu/pledge-for-s… European Parliament is about to discuss a complete ban for animal research. This is real and will be catastrophic for progress in the fight against many diseases. Please support @EU_Brain pledge:
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Carlos.Parras.Team retweeted
My thoughts on the phase 3 results of Alzheimer's drug lecanemab from Biogen and Eisai, presented at #CTAD #CTAD22 and published this evening in the @NEJM. Major takeaway – this is NOT the breakthrough we have been waiting for. Key points:
ALT Neuroitic plaque (stained green) surrounded by dystrophic neurites (faint red) and microglia (brighter red). SchragLAB
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I am delighted to tell you that our paper on Tensin3 is now available as html version in eLife doi.org/10.7554/eLife.80273, with a great layout and lots of shared data files. Thanks a lot to all the people involved! particularly to @EmericMerour and @TheHassanLab at @ParisBrainInst
I am glad to share with you our last study on Tensin3 and oligodendrocyte differentiation summarizing 8 years of work by @EmericMerour & Hatem Hmidan and collaborators at the @ParisBrainInst biorxiv.org/content/10.1101/….
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As promised @GordonConf#Myelin here is the revised version after Review Commons peer-review of our Tns3 paper, that has been submitted now to eLife. I hope you will appreciate the improvements.
biorxiv.org/content/10.1101/…
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