The gut is much more than a digestive organ. It is a metabolic sensing and signaling system that helps shape how we respond to food, regulate appetite, and control metabolism.
Really enjoyed going deep on this with Andrew Huberman, from gut biology and the microbiome to obesity, GLP-1 therapies, and endoscopic treatments.
The new Huberman Lab episode is out: Best Tools for Gut Health and Weight Loss | Dr. Chris Thompson
0:00 Dr. Chris Thompson
2:16 Digestive Tract, Gut Hormones & Nutrient Absorption
8:06 Colon Microbiome & Colon Cancer Screening
11:13 Sponsors: LMNT & Lingo
13:40 Swallowing Problems & Zenker's Diverticula
16:08 Bowel Movements & Constipation
18:28 Fiber, Resistant Starch & the Gut Barrier
21:50 Intermittent Fasting & the Gut Microbiome
23:38 Fermented Foods, Microbial Diversity & Butyrate
27:12 H. pylori, Stress & Stomach Ulcers
30:20 GLP-1 Medications: Benefits & Limitations
33:42 Lower GLP-1 Doses, Weight Regain & Muscle Loss
37:35 GLP-1 Side Effects, Food Noise & Apathy
39:49 Bariatric Surgery & Medical Innovation
46:07 Sponsor: AG1
47:44 Hunger & Satiety: Ghrelin, CCK, GIP & GLP-1
50:01 Retatrutide & Combining Hormonal Targets
52:55 Ultra-Processed Foods, Overeating & Leptin
55:32 Incretin Discovery, Exendin-4 & the Gila Monster
59:35 Endoscopic Ultrasound & Pancreatic Biopsy
1:07:40 Early Metabolic Markers, CGMs & Fasting Insulin
1:13:06 Insulin Resistance & Metabolic Flexibility
1:15:53 Sponsor: Function
1:17:35 Patient Data, Screening & Treatment Adoption
1:26:31 AI, Robotics & Improving Procedures
1:29:27 Choosing a Surgeon & Measuring Procedure Quality
1:35:29 Image Guidance & Hyperspectral Imaging
1:37:19 Sponsor: Our Place
1:38:56 Diagnostics & Targeted Metabolic Treatments
1:42:45 Gastric Bypass, Foregut Exclusion & Diabetes
1:47:59 Duodenal Liners & Mucosal Resurfacing Research
1:52:58 Gut Permeability, Inflammation & Fatty Liver
1:59:39 Artificial Sweeteners, Fructose, Fats & Omega-3s
2:05:00 Resistance Training, Zone 2 Cardio & Intervals
2:06:31 Weight Set Point & Metabolic Adaptation
2:08:13 Endoscopic Sleeve Gastroplasty & Fundus Ablation
2:10:30 Magnetic Intestinal Connections & Combined Treatments
2:16:52 GLP-1 Gene Therapy Research
2:22:13 Innovation, Problem Solving & Teamwork
2:25:58 Zero-Cost Support, Sponsors & Neural Network Newsletter
Includes paid partnerships.