Deviation Capital launches today as the spin-out of the Two Sigma Ventures business after nearly 15 incredible years of business! Follow @Deviationcap for what comes next.

Stretching runway, recruiting + retaining top talent, cutting through AI hype, navigating global compliance. @marcelolebre (@remote president and cofounder) + @csbeirne are discussing it all on Oct 2nd (6pm) in NYC. Founders, come through: luma.com/4yryd9b7

TSV is hiring a summer intern! We're on the hunt for a high agency undergrad or grad student who lives and breathes startups to join us in NYC this summer to help source deals, conduct market research, and evaluate investment opportunities. Our tight-knit and collaborative team structure means you’ll get the rare opportunity to gain high visibility across the entire investment process, connecting you with investors, portfolio founders, and the broader startup ecosystem. If this sounds like you, apply here: bit.ly/TSVintern

Debating tech’s future is better in person! On March 27th, we’re hosting our annual Salon, a four-sided debate on topics that impact our future. This year, we’re trying to get to the bottom of what sector the next $1T company will emerge from… AI Superintelligence, Infrastructure, Biotech & Healthcare, or Consumer. If you’re a builder or operator in one of these areas, come represent your sector and help us see the future through your eyes. We’ve got a few spots open, so make sure to RSVP below. lu.ma/q9so7pux

TSV portfolio company @dbnlAI was just put on @BuiltIn 's 2025 best startups to work for remotely (and in SF) list! Perfect time to share that they're hiring for 2 roles 🔥 Distributional: Building the modern enterprise platform for AI testing to make AI safe, reliable, and secure. 1️⃣ Senior Front End Software Engineer (4+ years of experience, remote) 2️⃣Senior Full Stack Software Engineer (4+ years of experience, remote) Apply here: distributional.com/careers/

It's not every day that your portfolio company's technology brings a new human life into this world! Major congratulations to @DinaRadenkovic and the entire @GametoGen team for hitting such an important milestone on your path to helping more families access IVF and making fertility treatments shorter, less invasive, and more accessible for all! Read more about the first Gameto birth below

Business banking needed an upgrade. Today it gets one thanks to @dakota_xyz . Businesses can now access modern banking that lets you send/receive USD & crypto globally, backed by US Treasuries, with automated yield generation built in. Now you can finally: - Send USD globally via ACH, Fedwire, SWIFT & SEPA - Make borderless payments 24/7 with stablecoins - Keep deposits 100% backed by US Treasuries - Earn automated treasury rewards - Access on-chain yield opportunities Incredible watching this team execute from pre-product investment to launch. Congratulations!

Scent teleportation is here. Games now build themselves in real time as you play. Menopause treatment gets funding to target the source, not symptoms. @Osmo_Labs teleported scent across their lab & taught computers to smell - first ever working digital olfactory system that can capture & recreate any scent. Plus, their public beta just dropped: imagine any scent in natural language, they'll bring it to life in their lab & send it to you @Etched launched Oasis - the first fully AI-powered game - generating & running entire playable worlds in real-time, creating new environments as you move @GametoGen secured $10M from ARPA-H to advance their menopause program Ameno - moving beyond symptom treatment to address root causes and help women maintain quality of life long-term TSV portfolio absolutely sprinting into the future this week 🔥🔥🔥

"With six people, we built, from scratch, the fastest laser melting platform on the planet... We did things people said you couldn't do." - Erik Palitsch, @freeform_future CEO / Co-Founder Since meeting the team, we've been blown away by their ability to execute - combining AI, supercomputing, and advanced sensing to completely reimagine metal 3D printing. Their momentum continues with today's exciting news –– a $14M raise from @nvidia and @Boeing! They're hiring across engineering and operations - check them out if you want to help shape the future of manufacturing! 👩🏻‍🏭 freeform.co/careers

A tiny chip, almost too small to see in the photo, could be the key to improving the speed, cost, and success rate of drug development. We got a firsthand look when @Terray_Tx's Jacob Berlin visited to share his vision last month. This nickel-sized chip (or microarray) is generating biological datasets 50x larger than public sources. Huge congrats to Terray on their $120M Series B funding round led by Bedford Ridge Capital and NVentures! As @endpointsnews reports, Terray is using this data to "train AI models to discover and design small molecules in a new way... placing AI's ideas at the center of its R&D process."

🚨 New TSV Investment: @Arda_Tx Harnessing data science to target chronic diseases, Arda is focused on eliminating disease-driving cells, not just modifying their behavior. Beginning with fibrosis, which contributes to 35% of global deaths, the potential is enormous. Read more about why we invested here: bit.ly/3Y59UDI

Enterprise AI adoption is at an all-time high, but so are the risks. Distributional's $19M Series A, which we're excited to have led, brings much-needed automated testing to AI systems! Read about why we think @dbnlAI can bridge the AI confidence gap here: bit.ly/4eSbHTg

Now you can get all the perks of a global business bank account — at the speed of crypto. 🎉Congrats to @dakota_xyz, a crypto-native bank for businesses, for launching out of stealth today! Read more about their launch below!

CALLING ALL AI INFRA BUILDERS! Join Two Sigma Ventures’ @dabelon & @vin_sachi as they dive into & debate the next 5 years of AI infrastructure with founders, academics, and operators: - @jefrankle, Chief AI Scientist @Databricks - @Zhou_Yu_AI, Professor @Columbia & Founder of ArticulateAI When? July 29th from 6:00 PM - 8:00 PM RSVP here: lu.ma/fa5a12an

TSV founder @csbeirne was live yesterday answering questions for @googlecloud #VCAMASeries! If you weren’t able to make it, here are a few highlights 👇

Have a question about TSV focus areas? What industries and technologies we're most excited about? How best to pitch us? Now's your chance to ask them. On Tuesday July 16th, TSV founder @csbeirne will be participating in the @googlecloud #VCAMASeriesSeries! Join him live alongside 300+ startups, and Ali Goldstein Norup as he shares insights on investing in the current VC market and Two Sigma Ventures ‘Must Watch’ list of industries. Snag your spot here: goo.gle/VCAMA-TwoSigmaVentur…

3/ Why is AI key to unlocking the "once-in-a-century" opportunity for drug development? "Just as popular chatbots like ChatGPT are trained on text across the internet, and image generators like DALL-E learn from vast troves of pictures and videos, A.I. for drug discovery relies on data. And it's very specialized data –– molecular information, protein structures and measurements of biochemical interactions. The A.I. learns from patterns in the data to suggest possible useful drug candidates, as if matching chemical keys to the right protein locks."

2/ The problem Bringing a new drug to market is expensive and time consuming, with most failing to ever make it past the clinical trial phase. "... the total expense is estimated at $1 billion on average. It takes 10 to 15 years. And nearly 90 percent of the candidate drugs that enter human clinical trials fail, usually for lack of efficacy or unforeseen side effects."

1/ GenAI is making computers "creative," but how does that apply to drug development? @SteveLohr @nytimes breaks down the "once-in-a-century" opportunity AI is ushering in for pharma in his recent article featuring TSV portfolio company @Terray_Tx. Let's dive in.

Announcing our investment in @Etched 's Series A! 🎯 Their mission: Solve AI's compute crunch. GPUs are hitting a wall; they’re getting bigger, but not necessarily better. 🗡 Their weapon: Sohu, a transformer-specific chip. 🚀 The potential: 20x faster AI at 1/20th the cost; That means real-time video gen, instant agents, & more. We're excited to be betting big on specialized AI hardware alongside Etched! Read more about their specialized chip (ASIC), Sohu, below.