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Andrés López Perrote retweeted
Online Now: CONCR lncRNA organizes a 3′-end structural domain that engages DDX11 for DNA replication and sister chromatid cohesion dlvr.it/TVD6XG
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Andrés López Perrote retweeted
starting to understand the structural bases of CONCR lncRNA in DNA replication and chromatid cohesion. A collaboration between @MaiteHuarteLab @FMorenoHerrero @OscarLlorcaCNIO @ChillonIsabel and the support of @FundlaCaixa
Online Now: CONCR lncRNA organizes a 3′-end structural domain that engages DDX11 for DNA replication and sister chromatid cohesion dlvr.it/TVD6XG
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Andrés López Perrote retweeted
Our take on the struture of the R2T complex 🌱 Now out in @Structure_CP!
A fun collab led by @alopezperrote and the @AlabadiDavid lab at @IBMCP .
Check it out in the next post 👇
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Andrés López Perrote retweeted
Hi, we have published a study in @Structure_CP that you may like it! This work is the result of a fantastic collaboration between our group @IBMCP and @LlorcaLab (@CNIOStopCancer), aimed at understanding the role of the HSP90 cochaperone R2T in plants doi.org/10.1016/j.str.2025.0… 👇
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Andrés López Perrote retweeted
Online now! The structure of the R2T complex reveals a different architecture from the related HSP90 cochaperone R2TP dlvr.it/TJC8Zg
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Andrés López Perrote retweeted
The γTuRC saga goes on!
This time, we used cryoEM to describe how CDK5RAP2 helps nucleating microtubules by activating the γTuRC nucleator.
Another tour de force led by @sernarina and Fabian Zimmermann and a fun collab with @LudersLab @IRBBarcelona.
authors.elsevier.com/c/1jpyq…
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Andrés López Perrote retweeted
Thrilled to share our last work @CellRepPhysSci Revealing the molecular mechanism of an anti-tumoral compound inhibiting our favourite system, RUVBL1/2 (at 2.4 Å resolution)🔥
All-@LlorcaLab work led by @CarmenBePaper and @alopezperrote
Link below 👇
doi.org/10.1016/j.xcrp.2024.…
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Andrés López Perrote retweeted
And also... 🔥pre-print alert🔥
We take a look at our favourite system in plants🌱, the R2T complex, an HSP90 co-chaperone.
A study led by @alopezperrote (@CNIOStopCancer) and Alberto Palacios (from @AlabadiDavid's lab at @IBMCP).
Check it out 👇
biorxiv.org/content/10.1101/…
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Andrés López Perrote retweeted
Big congratulations to our new #CNIOStopCancer PhD Dr. Natalia Cuervo Iturrioz! 🎉
👉#CNIOPhDThesis: 'Human WAC is a partner of chaperone complexes involved in the assembly and activation of mTORC1'.
Exciting times are ahead! 👏
🎓Directors: @OscarLlorcaCNIO and @sernarina.
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Andrés López Perrote retweeted
PAPER ALERT🔥
We took a deep dive into the microtubule 🔍 using cryoEM ❄️🔬to capture the earliest steps of nucleation by the γTuRC complex. With @sernarina and @DeBritoClaudia leading the way.
Proud of our collab with the @surrey_lab at the @CRGenomica !
science.org/doi/10.1126/scie…
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Andrés López Perrote retweeted
Thanks to #CNIOStopCancer colleagues for these two days of retreat full of ideas and inspiring talks. Shared time makes stronger teams!! 😃
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Andrés López Perrote retweeted
📸Hoy hemos mantenido una reunión de seguimiento del consorcio que coordina nuestra investigadora @MaiteHuarteLab, en el que participan @CNIOStopCancer y @CNB_CSIC
🔝Proyecto que busca nuevos tratamientos para el cáncer colorrectal financiado por #CaixaResearchFundlaCaixa
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Andrés López Perrote retweeted
Great meeting @CIMA_unav together with @LlorcaLab and @MaiteHuarteLab in the context of our @CaixaResearch project! Thank you Maite for hosting us!!
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Andrés López Perrote retweeted
Great @Tec4Bio meeting with all our members and finally in person!🎉 @FMorenoHerrero @AlegreCebollada @madelpozo67 @OscarLlorcaCNIO Ricardo Garcia @icmmcsic and Gustavo Plaza @La_UPM
Thanks to @XavierTrepat and @RuedaLab for taking part in it. Looking forward the next one.
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Andrés López Perrote retweeted
Just out! RUVBL1/2 strikes back, this time together with ZNHIT2, a complex involved in the maturation of PRPF8. The great @sernarina, @AnaCorpalez, Sofía Cabezudo and @alopezperrote spearheading this project. Full text link below 👇
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Finally out in @eLife ! Cryo-EM reveals the regulation of RUVBL1 and RUVBL2 AAA-ATPases by DHX34, a helicase involved in NMD @LlorcaLab @alopezperrote @CNIOStopCancer. In collaboration with @nelehug @JavierFCaceres1 @mrc_hgu.
elifesciences.org/articles/6…
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Andrés López Perrote retweeted
Have a look at our latest review on the RUVBL1–RUVBL2 complexes. Great work by Maria I Dauden, and @alopezperrote @OscarLlorcaCNIO done at @CNIOStopCancer.
sciencedirect.com/science/ar…
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Andrés López Perrote retweeted
Very happy about our collaboration with Oscar Llorca, Andres Lopez-Perrote and colleagues at CNIO
Cryo-EM reveals the regulation of RUVBL1 and RUVBL2 AAA-ATPases by DHX34, a helicase involved in NMD is now out
@biorxivpreprint @LlorcaLab @CNIOStopCancer . In collaboration with @nelehug @JavierFCaceres1 @mrc_hgu.
bioRxiv 2020; doi: doi.org/10.1101/2020.09.28.3…
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