Vice Chair, Member, Mskcc Director of Head and Neck Cancer; Director of proton therapy

New York, NY
🗣️🔇@JamesBatesMD from @WinshipAtEmory/@UNC presenting ctHPVDNA-Adapted Adjuvant RT. Note that ctDNAneg group still got RT (reduced dose). @ASTRO_org #ASTRO26 @DanielMaMD @ctdnaMD @LChen_MD @yaoyu_md @xrtGenomics @imrtlee @NavDxTest @ScottBratman
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🚨‼️Happening now - technology driven strategies for HNSCC. First talk - @imrtlee on FMISO pooled analyses. #ASTRO26 @ASTRO_org @xrtGenomics @seanmmcbride @MSK_RadOnc
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Coming up at #ASTRO26: MSK radiation oncologist @imrtlee will present a pooled analysis of trials studying FMISO PET-guided, lower-dose radiation for HPV-positive oropharyngeal cancer. @ASTRO_org 🗓️ Sunday, September 27 | 3 p.m. ET Learn more: bit.ly/4yYOmcE
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📜 In @JNCI_Now, we present "A phase II randomized study of proton therapy vs intensity-modulated radiation therapy in patients with unilateral head and neck cancer" Thank you Drs @imrtlee @xrtGenomics & team @MSKCancerCenter @MiamiCancerInst @MayoRadOnc pubmed.ncbi.nlm.nih.gov/4269…
🔵 Phase 2 (n = 98)randomized trial of proton beam RT vs IMRT in postoperative unilateral #HeadAndNeckCancer ➡️ Clinician-graded grade ≥2 mucositis 7.4% vs 22.7% (P=.03), dysgeusia 9.3% vs 31.8% (P=.005). 🔗: oxford.ly/4Ay4H9V @IMRTLee | @xrtGenomics | @EChrisDee
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Nancy Lee retweeted
🎥 President’s Member Spotlight: Learn from Alison Tree, MD (Res) ASTRO President Dr. @NehaVapiwala speaks with Dr. @alison_tree, MD (Res), a Doctor of Medicine by Research and consultant clinical oncologist at The Royal Marsden specializing in radiotherapy and chemotherapy treatment for urological malignancies. Watch on YouTube: bit.ly/4ruWaQQ Watch online: bit.ly/3TqiwGq @IJROBP
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Nancy Lee retweeted
🔵 Phase 2 (n = 98)randomized trial of proton beam RT vs IMRT in postoperative unilateral #HeadAndNeckCancer ➡️ Clinician-graded grade ≥2 mucositis 7.4% vs 22.7% (P=.03), dysgeusia 9.3% vs 31.8% (P=.005). 🔗: oxford.ly/4Ay4H9V @IMRTLee | @xrtGenomics | @EChrisDee
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Nancy Lee retweeted
🎓 Thrilled to have hosted Prof. Alison Tree as a Visiting Professor at @MSKCancerCenter @MSK_RadOnc. A fantastic day of discussion around prostate cancer, clinical trials, innovation in radiotherapy, and where our field is headed next. Thank you Alison for sharing your insights and experience with our faculty, trainees, and broader MSK community — and for the many thoughtful conversations throughout the visit. 🇬🇧 ➡️ 🇺🇸 Grateful for your visit to MSK, @alison_tree!
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With the shift towards Ind Chemo in #NasopharyngealCarcinoma #NPC many unanswered questions remains: We highlight them in this month's RedJ editorial @ASTRO_org @sueyom @lachiemcd 1. Optimal no of cycles 2. Utilising on-treatment response 3. How do we manage poor responders to IC - midway switch or stop at 2 4. What about non-endemic and EBV- NPC Free link below for 50 days! ⬇️ sciencedirect.com/science/ar…
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Congratulations to Zaza Gelashvili, a graduate student in the lab of cell biologist Dr. Philipp Niethammer at the @GSKGradSchool, who recently received the 2026 Chairman’s Prize, an annual award established by Louis V. Gerstner Jr., GSK Board of Trustees Chair Emeritus and namesake of the school, to recognize an outstanding GSK student who is the first author of research published in a scientific journal. Zaza's work has uncovered new ways that cells sense physical change and turn that information into coordinated responses. “This award encourages me to continue pursuing fundamental questions in basic research, where some of the most revealing results emerge when biological systems do not behave as predicted," says Zaza. Congratulate Zaza below and learn more about his research here: bit.ly/3V8wVaS
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Research led by Dr. Agnel Sfeir’s lab at MSK identified a hidden structural weakness in rogue DNA found in aggressive cancers. In lab studies, blocking the protein that repairs this DNA caused it to become unstable and gradually disappear from cancer cells. Learn more: bit.ly/4hljOL3
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Nancy Lee retweeted
Most RT-drug combos bet on synergy. Yet synergy is rare (most combos only additive). We're chasing a bar most of oncology can't clear. Our phase 1s don't even measure it. ProjectOptimus for #RadOnc & our editorial in @IJROBP w/Gustav, Ezra & @imrtlee - doi.org/10.1016/j.ijrobp.202…
Must listen and must read!! See also accompanying commentary by Nadeem Riaz @xrtGenomics which should be out soon in @IJROBP #RedJournal #radonc #radbio @finn_corinne @sueyom
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Memorial Sloan Kettering Cancer Center (MSK) and @OpenEvidence have partnered to bring cutting-edge AI and precision oncology expertise closer to the point of care. By integrating OpenEvidence into MSK's Epic workflow and embedding MSK's @OncoKB™ precision oncology knowledge base directly into OpenEvidence, clinicians can access trusted, evidence-based insights within their existing clinical workflows. “We're excited that OpenEvidence will widen OncoKB's reach, bringing MSK's expert interpretation of a patient's unique cancer genetics to cancer care providers across the U.S. to help them make molecularly informed treatment decisions,” says Dr. Debyani Chakravarty (@CDebyaniPhD), a lead scientist for OncoKB at MSK. Learn more about this new collaboration: bit.ly/4AiLZTt
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Congratulations to the team at @MSKCancerCenter/@MSK_RadOnc! Especially @imrtlee for the tireless advocacy for this effective, practice-changing strategy to safely cure oropharyngeal cancer with minimal side effects. @seanmmcbride @xrtGenomics @ScottBratman @sueyom
🚨 The @FDA has granted “Breakthrough Therapy” designation to FMISO, a specialized imaging tracer that can help identify patients with #HPV-positive #throatcancer who may safely receive less-intensive radiation treatment. “This has been an absolute game changer for treating certain people with throat cancers caused by the human papillomavirus or HPV,” says MSK radiation oncologist @imrtlee, who pioneered the approach. Learn more: bit.ly/4AbDBoW
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Leading experts in #cancerresearch, including Dr. @AndreaCercek, a gastrointestinal medical oncologist at MSK, reflected on the significant strides made in tackling the disease, along with the work that remains to be done toward finding a cure, at the TIME100 (@TIME) Health Leadership Forum in New York. Dr. Cercek, who was also a 2025 TIME100 Health honoree, highlighted the growing potential of #vaccines and immunotherapy to harness the immune system to fight cancer. “The hope … between vaccines and immunotherapy as well is that they harness the immune system, which is really the most powerful drug we have,” she said. “It can fight anything as long as it’s equipped to do so and it recognizes something is foreign, and so it’s really that combination that needs to happen for therapy to work.” Read more: bit.ly/4xi6Fs4
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Nancy Lee retweeted
🚨 We’re hiring at MSK! 🎯 Director, Metastatic Disease Team 👥 Lead ~20 faculty 🧪 Drive innovative trials 🔬 ~50% research time (track-dependent) 🌐 Shape care across @MSKCancerCenter Help define what’s next in @MSK_RadOnc. 🚀 Contact @seanmmcbride if interested. Click here for more details: msk.wd108.myworkdayjobs.com/…
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🚨 The @FDA has granted “Breakthrough Therapy” designation to FMISO, a specialized imaging tracer that can help identify patients with #HPV-positive #throatcancer who may safely receive less-intensive radiation treatment. “This has been an absolute game changer for treating certain people with throat cancers caused by the human papillomavirus or HPV,” says MSK radiation oncologist @imrtlee, who pioneered the approach. Learn more: bit.ly/4AbDBoW
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Nancy Lee retweeted
I wrote about the state of AI, why I’m concerned about the next few years, and the choices we need to make to keep the future in humanity’s hands. An Alien Mind: openai.com/index/an-alien-mi…
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African wild dogs in #Zambia! The pups emerge from the den eager to play and curious about the world. The strength of the pack makes them a formidable force. #teamwork
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Nancy Lee retweeted
Thrilled to share our latest work out now in CIR. We uncovered paradoxical role of EphA4 in HNSCC: it drives tumor growth when in Tregs, but suppresses it in CD8+ T cells, myeloid cells, and cancer cells. The secret? Upstream negative regulation of AKT. pubmed.ncbi.nlm.nih.gov/4264…
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