We've all quietly accepted that antibodies don't work.
We all ordered 4-5 at 500 USD each, test them, keep whichever one binds. In any other context that's buying 5 phones and planning to throw away 4, which is crazy.
Seems now ~18,000 vendor validation images across 15 catalogs were manipulated.
Reminds me also of a prior study that found more than half of commercial antibodies didn't work as advertised. Estimated cost, over 1 billion USD a year.
...such a waste of research money.
"More than 18,000 questionable images found in antibody catalogues of 15 companies" - It's stuff like this that makes bio research so slow