An excellent review of our recent paper on mitochondrial control of fuel switching – thank you!! The bottleneck of fat burning | Science science.org/doi/10.1126/scie…
To our surprise, the carnitine biosynthesis pathway influences the optimal efficacy of GLP1-based anti-obesity therapies! You can see the full MS here until it lasts: science.org/eprint/ARC749JWZ….
Our body (cells) have fuel preference, e.g., burning fat vs. carbohydrates, which depends on the environment and nutritional states. How do cells decide which fuels to use? Our new study found that carnitine biosynthesis is crucial for fuel switching science.org/doi/10.1126/scie…
I am honored to write this award lecture article as a single author, but it reflects the collective effort of our fellows, students, and collaborators. Thank you all for being part of this journey! Lecture video available diabetesjournals.org/diabete…
Adipose tissue generates heat even in the absence of UCP1. How does it work? Our new work identifies a molecular “resistor” of Ca2+ cycling that makes heat and controls energy metabolism through a UCP1-independent mechanism. sciencedirect.com/science/ar…
Thank you! This is an incredible honor. I would like to thank my mentors, colleagues, and all the fellows who have worked with me over the years - Please come join us at ADA in Chicago!
Yay Shingo! • Shingo Kajimura, PhD is the recipient of the 2025 Outstanding Scientific Achievement
Award of the ADA, which recognizes research in diabetes that demonstrates particular independence of
thought and originality. @KajimuraLab
This is an excellent effort by leading scientists in the field of brown fat to discuss currently debated topics and how to resolve them. Thanks to all the authors who contributed to this perspective!
Exciting work from Christine Kusminski and Phill Scherer's group showing the futile Ca2+ cycling in adipose tissue in response to GIP. Congratulations!!!