Prof. @ Harvard University, Broad Institute, & Wyss Institute. Understanding the natural world by building a synthetic one. Website: khalillab.github.io

Boston, MA
Attn eVOLVER users & enthusiasts. 2 BIG developments! 1) New open-source eVOLVER wiki, which will be a hub for guides and documentation: khalil-lab.gitbook.io/evolve… 2) eVOLVER software version 2.0 is now available! Read about the new features on the forum: evolver.bio/t/evolver-wiki-s…
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We're searching for an assistant/associate professor in Bioengineering at Stanford! If you're using cutting-edge engineering approaches to understand or control biological systems in useful ways (medical, environmental, etc), we'd love to hear from you! facultypositions.stanford.ed…
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Mo Khalil retweeted
🚀 Interested in joining my group as a PhD or Postdoc? I'm mentoring for the ETH AI Center's Doctoral and Postdoc Fellowship, working on biomolecular design. If you're excited about AIxBio, I'd love to hear from you. Apply now 👉 ai.ethz.ch/apply Deadline: Oct 27, 2026
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Looks amazing 🤩
1/17 Submissions are now open for the 2027 Microbial Population Biology GRC! We expect this meeting to be extraordinarily oversubscribed. If you want to come, time is of the essence--apply early! June 27–July 2 • Andover, NH grc.org/microbial-population…
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Mo Khalil retweeted
Could the folding of synthetic gene circuits in 3D shape how genes are expressed? Today @ScienceMagazine we report on the role of gene syntax in shaping feedback between transcriptional activity and genome folding for advanced circuit design🧵 (1/n)
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Princeton postdoctoral fellowship opportunity to work in my lab & others! This opportunity is part of a new NSF-funded center here, and is focused on candidates who are interested in biomolecular condensates and programmable soft materials. Deadline Nov 1. apply.interfolio.com/193107
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We’re hiring a Technical Assistant I/II in the Weissman Lab @WhiteheadInst to work on in vivo functional genomics with multimodal readouts. Our technicians have had incredible success going on to PhD & MD/PhD programs. Apply or send great candidates our way!
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📢 Our Dept. of Systems Biology @Columbia has a faculty opening in the broad area of quantitative biology (Comp/AI/Bio, etc.). Come join our department in NYC! Please circulate/RT. Apply: apply.interfolio.com/192256 Deadline: Nov 1, 2026. @ColumbiaSysBio systemsbiology.columbia.edu/…
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Cells mitigate damage to DNA in surprising ways. Using a series of CRISPRi chemogenomics screens, we identified a PRDX1-dependent iron–damage axis in the DNA damage response. Congratulations to Tom, Abe, Shaheen, Josep and all co-authors! doi.org/10.1038/s41589-026-0…
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We are hiring! 🌟 Dept of Biochemistry and Molecular Biology at the University of Chicago is searching for a tenure-track assistant professor. It's a broad search: we want great colleagues doing serious biological work at the molecular scale. Please share! apply.interfolio.com/191981
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Mo Khalil retweeted
Excited our ratiometric transcriptional activation (RTA) work led by @Melissa_Gray234 is out online today @CellCellPress! Measurements determine what we can discover in biology; we use RTA to turn protein abundance changes into amplified signals. cell.com/cell/fulltext/S0092…
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Excited to share our new preprint! We asked how inducible SynNotch-CAR circuits can better discriminate on-target from off-target cells when they share similar antigens. biorxiv.org/content/10.64898… Congratulations to Daniel Hoces, Jaclyn Ng and Julian Perez!
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We’re #hiring! In partnership with @PrincetonCS, we invite applications for new faculty positions in the area of Computational Bioengineering, at the Assistant, Associate, or Full Professor rank. Find out more and apply here: apply.interfolio.com/191394
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When training protein language models, people usually discard metagenomic proteins that don't cluster with at least 1 other protein (singletons). With @riavinod_ @Samir_char @avapamini @lorin_crawford , we show that this is probably not the right strategy.
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Mo Khalil retweeted
New paper from the lab! authors.elsevier.com/sd/arti… We find that protein degradation is broadly slower in human segmentation clock cells than in mouse cells, regardless of the degradation pathway or protein category! 1/
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Huge faculty recruitment effort at the University of Chicago -- a division-wide, open-rank search looking to hire about 20 faculty across 5 research areas in biology. Come be our colleague! Full announcement: uchicago.app.box.com/s/ckih9…
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🚨Two complementary preprints from our group reveal convergent mechanisms of inherited B-ALL predisposition. Check out this terrific work led by @LWahlster, @ALNeehus & #AndrewLee! biorxiv.org/content/10.64898… biorxiv.org/content/10.64898…
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Mo Khalil retweeted
I am happy to share that we are recruiting a postdoc with previous #tuberculosis research experience for a Mtb systems biology project focused on gene networks! Please visit our lab website (jasonyanglab.org/) and our ad (tinyurl.com/ms92bmj8) for more information!
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