1/ Keen to share the story of my postdoc research in @TheXavierLab! We built a massive resource characterizing the spatial landscape of the gut, and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇
nature.com/articles/s41586-0…
Excited to share our latest study uncovering gut microbes and microbial metabolites linked to cardiovascular health! We show that Oscillibacter is associated w/decreased cholesterol in human subjects & that these bacteria take up &metabolize cholesterol.
bit.ly/4cGpnjW
Our latest preprint, profiling gene regulation in >670 developing human brains!
Driven by exceptional PhD student @cindywen2019
"Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain." medrxiv.org/content/10.1101/…
Excited to share a pre-print of our work in the @KiesslingGroup describing interactions between human lectins and stool microbiota. Some highlights below: (1/4)
Among billions of potential microbiome epitopes hide few immunodominant 'keystone' epitopes recognized by T cells. Out today in @ImmunityCP, we discover keystone epitopes and show T cell responses to reflect intestinal immune health. cell.com/immunity/fulltext/S…
Multi-omic profiling in IBD patients initiating biologic therapy identifies remission-associated gut microbial features. Our findings provide a foundation for more individualized selection of optimal therapeutic agents. Online now @cellhostmicrobe:
sciencedirect.com/science/ar…
In a collaboration with the Weersma lab out now in
@NatureComms, we show that intestinal mucosa cis-eQTLs in IBD can depend on inflammatory status and be influenced by the cell type composition of the mucosa.
Read about this work:
nature.com/articles/s41467-0…
Ready to work at a mission driven company? Want to use your talents to help us attain health equity? Join us! We are hiring a full stack engineer and a bioinformatician.
#WomenInSTEM#Jobs#Hiring#STEM
Now out! From @GeschwindLab@UCLA : Abnormal social and repetitive behaviors and elevated striatal dopamine, a molecular hallmark of human psychosis, in a Maternal Immune activation non-human primate model biologicalpsychiatryjournal.…