Japanese scientists removed the extra chromosome that causes Down syndrome for the first time using CRISPR.

Ah yes, excellent points. We shouldn't worry about AI risk, because remember, your ancestors were ravaged by tiger attacks, bubonic plague, smallpox, famine, earthquakes, and the Nazis. Thankfully there was always someone with a name like BoneGPT to stand up in the back and shout "STOP WORRYING ABOUT IT, ACCELERATE," and that's why we're here today. It definitely wasn't because people banded together and SOLVED these problems by inventing vaccines, building sewers, forming alliances, and studying the earth. You're naming problems that humankind has worked desperately over millennia to solve, as though it's evidence that problems just solve themselves. For none of these things did we say FUCK IT, IT'LL PROBABLY BE FINE IF WE DO LITERALLY NOTHING. It's the opposite: these are all stories about generations who fought valiantly to eliminate risks so that we, their successors, could live without them. It's on us now to do the same. There WERE people at the time who for each of these things said, fuck it, God will save us. Those people are not our ancestors. Our ancestors were the ones who got their shit together, solved these problems, and survived. AI doesn't became safe on its own. We have to actually SOLVE safety and learn how to control these things. And we will. It took enormous work to make sure planes don't fall out of the sky, or that space shuttles don't spontaneously combust, but we got there. But we have to actually do it. We don't get to just talk about it. We are going to willingly give control of almost all of the levers of society to AIs pretty soon. So we better be absolutely fucking sure that when we do, we're still in charge.

"People aren't ready, this is gonna change everything" You know what people weren't ready for? Fucking mammoths. Tigers eating them. Monkeys ripping their arms off. The black plague. The ice age. Smallpox. Vikings pulling up on the beach. Drinking water that gives you diarrhea until you die. Getting a scratch and losing your whole leg. The Mongols. The Spanish Inquisition. One volcano can send us back to the dark ages and these safety guys are gonna be shocked. Oh the robots didn't kill us? It was a volcano? Imagine their disappointment as the hot ash rains down on them. A solar flare is gonna explode your phone in your pocket your legs are gonna be covered in battery acid and your bank account will stop working. You're afraid of a computer program doing math? "Things are moving too fast" homie you live on a rock that periodically deletes everything. You are one the most luckiest entities in a 100 light year radius living during a golden era. Cheer up. My ancestors crossed an ocean in a wooden box because they ran out of fucking potatoes. "The social disruption will be enormous!" Nigga World War 2? World War 2? Hop in the people carrier we're landing on the beach. Are these people out of their fucking minds? Do they not know what we've survived already? A couple decades of air conditioning and people suddenly think oh this is the natural condition of mankind. No. We used to have eight kids because seven didn't make it. You're gonna be fine. Man the fuck up. Accelerate.

What struck me about this photo is that Trump and Xi invited to their dinner table: an immigrant from South Africa, two Taiwanese immigrants that came to the US as children, and a gay kid from Alabama, all of whom moved to Silicon Valley to make a dent in the universe.

Be Bitget’s CEO @GracyBitget Run your own market-making shop using customer data Mock Hyperliquid over an exploit, call it FTX 2.0 Then have your own MM algo misfire… for 2 hours straight Lose $100M+ exactly like FTX did in ‘21 with $MOB Act like nothing happened GG, WP

1/ Huge respect for Dragonfly continuing to invest in the bear market. But I'm morally obliged to call out sketchy projects gaining momentum. As a community we must preempt large scale implosions like #FTX or #LUNA that set the industry back years Bitget may be the next FTX 🧵

Legacy media REFUSED to show you a SINGLE SECOND of President Trump's speech and historic state dinner with Xi Jinping tonight at the White House So here's the ENTIRE thing, from start to finish, with translations for Xi's speech DO NOT LET LEGACY MEDIA KEEP YOU IN THE DARK

Likely got rugged by another person this month I recovered $275K stolen by Indian call scammers. Have been ghosted for 4 weeks about my % while they’re active on X. Since June 2026 it’s now been three people rugging me for ~$100K total reward…. Has ruined my motivation to reply to cold messages and only reply to referrals from strong mutuals.

An anti-AI protest outside Google’s offices today. Note the presence of a Palestinian flag. Can someone please explain the alignment between the Palestinian and anti-AI protestors?

Interesting how irrelevant Binance has become to the crypto trenches. None of the major runners are listed on Binance and all price discovery happens onchain. And perp dexes taking their perp volumes too. Plus, tokenized stock meta requires licenses and regulations that Binance lacks so their regulatory arbitrage isn’t paying off in this meta. CEXs are mostly good for fiat onramp/offramp. But even for this Binance isn’t an option in the US and the EU.

Real. I remember back in 2023 if a new project had a Binance listing it was like: "Hell yeah, this will pump hard AF, I'm aping on launch". Today it doesn't matter anymore. Hilarious when they listed Broccoli 714 and Bananas 31 back in 25' too. Their reputation fell off a cliff during this bear market. And Binance not listing $HYPE initially may go down as one of crypto’s great generational fumbles (eventually they listed perps though, but not spot). CZ's stubbornness was the start of their downfall.

Let’s clear up a misunderstanding. “BTC is pristine collateral” It is for them, NOT for you. When you borrow, front the stinkiest dogshit collateral they will take. For example your home loan... The bank doesn’t even know how much it’s worth. Takes months to sell. They pray you don’t default, it’s a risk for them. BTC as collateral. They know what it’s worth EVERY SECOND OF THE DAY OR NIGHT. Insta-liquidation is easy. They are incentivised to liquidate, charge penalties and roll the money to the next borrower. So remember… when you borrow let them take your dogshit.

1/ gm. gm. Name is Hsin-Ju. I have a dark, kinda tragic personal announcement. I've decided I'd rather take $0 than accept a settlement that requires me to stay silent about what happened to me. I have since fired my lawyers at @sanfordheisler & will be releasing all the evidence from my time @hack_vc on Wed 8/26. INTRO: I've been in crypto for 9 years. Most recently I was a partner & head of platform @hack_vc which is a $600-700M crypto VC firm. Many of you may know me from my time as Head of Growth at @StellarOrg in 2017 (worked w/ the Mt. Gox founder), @Solana in 2018 (joined under ~10 ppl, but quit before my cliff), & @Fhenix in 2024. Or have attended one of my @DystopiaLabs ETH events (2019-now). Last year, I was forced to work through a serious medical emergency while at @Hack_VC due to threats by @alpackaP @dbulaevsky, saying that they would blacklist me from the space if I quit before finishing the hacksummit conference & side events that I was helping with during @kbwofficial. I was working 13-14hr days, 6 days a week, sleeping 0-4 hrs a night, and had documented Graves' disease, hyperthyroidism, and severe insomnia. I repeatedly asked to quit. Hack VC refused. This + other threats and intimidation went on for almost a month. The conditions got so bad I attempted suicide. The fucked up part is that, even after the suicide attempt, I told everyone at Hack VC (in writing) that I had no plans to sue. I was scared & extremely sick. I just wanted to leave. I told them that as long as there was no retaliation or badmouthing - I had no plans to sue. @Hack_VC chose to retaliate. After just 1 month after my near suicide, Hack VC mishandled my COBRA health insurance, refused to fix things, kept shooing me to customer support (when it's legally Hack VC's responsibility to fix this), and my insurance had issues and was not fixed for almost 4 MONTHS. Hack VC did not fix everything until I hired lawyers and had them force Hack VC to adhere to the law & fix my COBRA insurance issues. The sheer cruelty of an employer harming someone's health insurance almost immediately after they nearly committed suicide is extremely fucked up. And, even during the legal engagement, Hack VC continued to lie & attempt to harm me through their lawyers and other employees/partners (multi-million dollar carry & clawbacks can make even the nicest ppl willing to turn the other way or lie). @0xRodney @IsTheBaron @roshunpatel @Alex__Botte. Now. Almost an entire year of engagement & my near suicide anniversary coming up, our lawyers (mine & Hack VC's) have reached the point of preparing for private mediation and settlement. And...I realized that I just can't do it. I don't want money in exchange for silence. I'd rather speak. I fired my lawyers yesterday. In case it needs to be said, I did a good job at Hack VC. I was only there full time for 7 months; been part-time since 2021. I got a $50k raise to $300k, $30k bonus, and promises of additional carry that would have been implemented about a week or so after my last day. I was also offered admission into the GP entity (but not sure if admission was actually completed bc it was during my medical emergency). This + my resume, should show that me suing is not a money grab; I was genuinely harmed. I'm aware that I'm just one person (who is not rich) facing a $600-700M VC institution. I've been told by @alpackaP that he's known most of the managing partners at most VC firms for almost a decade and he could absolutely blacklist me. I'm also painful aware that the conclusion of this will probably be extremely poor for me or death - but I've accepted it. Sharing with other web2 & web3 VCs: @paulg @ycombinator @500STARTUPS @a16zcrypto @PanteraCapital @dragonflyvc @RaceCapital @hosseeb @haunventures @hiFramework @ElectricCapital @blockchaincap @Delphi_Digital @variantfund @1kxnetwork @archetypevc @shimacapital @robotventures, etc. TLDR; I’m done with continued threats, pressure, and intimidation. I'm not going to take a payout and allow Alex or Hack VC to walk away from harming me. As mentioned, I'll be dropping the evidence from my case on Wed 8/26 (or before) -- privacy be damned. Support here (or DM) please: ETH: 0x68c10776C5c05Cbf5B4C2318bE02D61B9f06B875 SOL: B7S8TPcWWJXTsmgG8ShoTmy8sNPuJ3Dbmt7z5gLFAveq

They just started calling ai.... SUPER intelligence As if they knew about our next phase There is only one SUPER token $SUPER cycle Dare to dream a little bigger

When @coinbase faced an existential threat from the SEC, @JohnEDeaton1 stepped up. John filed a brief in support of Coinbase’s position on behalf of 4,701 Coinbase customers. And, just as in the Ripple & LBRY cases, John was PAID NOTHING for those services. When Coinbase (and the whole industry) were in trouble, @JohnEDeaton1 stepped up because that’s who he is—ONCE A MARINE, ALWAYS A MARINE. 🇺🇸 Now John needs our help. The only question is: Will industry leaders like @brian_armstrong step up to support @DeatonforSenate ?

Lots of X hacks happening rn Latest is @PolicyCase which was QWERTY They are now gonna try to DM others looking like an official X acct and phish more (REPORT THIS!) If you see my account put up some time sensitive post about an airdrop or nft mint or smth DO NOT CLICK!!!

The race for AGI Script: Sherpa by Pocket FM Video: Seedance 2.5

Quantum computing just got a little less serious. You can now launch coins paired with $IONQ, from @IonQ_Inc on StonkFun. stonkfun.xyz/launch Powered by @Sunrise and @Backpack.

Earn rewards for holding, rebuy $KNOTS, repeat. Autocompounding is live on @jtx_trade