Aram Chung@ac467

Prof at Korea Univ / Co-founder & CEO of MxT Biotech

 Seoul, Republic of Korea
aramchung.com
Joined October 2010
40 Photos and videos
Aram Chung retweeted
ResearchHub
@ResearchHub
Sep 16
Jang et al., Microfluidic Mechanical Reactivation of Senescent Stem Cells, Small (Wiley, 9 September 2026), Konkuk University and Korea University, Seoul; figures cited from the bioRxiv preprint version. onlinelibrary.wiley.com/doi/…

Microfluidic Mechanical Reactivation of Senescent Stem Cells

This study introduces μ-CPR, a microfluidic platform that reactivates senescent stem cells through controlled mechanical stimulation, without chemical or genetic intervention. μ-CPR restores intrac...

onlinelibrary.wiley.com
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A study from @GDE_UTSW developed a polymer-lipid hybrid nanoparticle platform enabling programmable encapsulation and controlled organ-specific delivery of diverse RNA payloads. Learn more: go.nature.com/4zPsMbD.

Tunable polymers for polymer–lipid hybrid nanoparticles facilitate controlled organ-selective RNA...

Nature Chemical Engineering - A polymer–lipid hybrid nanoparticle platform enables programmable encapsulation and controlled organ-specific delivery of diverse RNA payloads. Through rational...

nature.com
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Microfluidics-mediated spatial control of mRNA lipid nanoparticles primes translation and enhances vaccine potency go.nature.com/4rpmX0I

Microfluidics-mediated spatial control of mRNA lipid nanoparticles primes translation and enhances...

Nature Biomedical Engineering - A microfluidic method restructures preformed lipid nanoparticles by inserting a metabolic-enhancing RNA into an internal peripheral compartment while relocating the...

nature.com
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Our recent work on microfluidic mechanical reactivation/rejuvenation of aged stem cells has been published in Small
Aging Science News
@AgingBiology
Sep 15
Microfluidic Mechanical Reactivation of Senescent Stem Cells onlinelibrary.wiley.com/doi/…
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Lipid nanoparticles chart path beyond the liver nature.com/articles/s41587-0… [🔓read free with login]
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For readers interested in the potential of in vivo CAR-T cell therapies for cancer and autoimmune diseases, here's a comprehensive review by pioneers in the field rdcu.be/koc33UDidsza nature.com/articles/s41573-0…
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RT @DengYanxiang: Excited to share that Spatial Hi-C-RNA is now out in @CellCellPress! It brings the 3D genome into spatial multi-omics by…

Integrative spatial profiling of 3D genome organization and gene expression in tissue

Spatial Hi-C-RNA simultaneously maps genome architecture and gene expression from the same tissue, revealing how spatial genome organization shapes cellular identity, development, and tumor evolution...

cell.com
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Aram Chung retweeted
CRISP_SCIENCE
@ScienceCrisp
Aug 15
”Genome-wide CRISPR screening identifies cellular factors controlling nonviral genome editing efficiency” Shivani Saxena, Meha Kabra [..] Krishanu Saha Nat Commun. 2026-08-13. doi.org/10.1038/s41467-026-7… #CRISPR #DDS

Genome-wide CRISPR screening identifies cellular factors controlling nonviral genome editing...

Nature Communications - Low editing efficiency of nonviral delivery in post mitotic tissues presents a challenge to the field of gene therapy. Here, authors dissect the genetic regulators of...

nature.com
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mRNA technology is one of the platforms being used for n-of-1 therapies. Read about its application in this and a range of other areas such as in vivo CAR-T cell therapies and cancer immunotherapies in this Review nature.com/articles/s41573-0… rdcu.be/fteeb
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Aram Chung retweeted
Waggoner Lab@LabWaggoner
Jul 10
Multifunctional-engineered NK cells overcome tumor immunosuppression by combining PD-L1 and HLA-E targeting and endogenous IL15 production 🇮🇹 nature.com/articles/s41392-0…
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Single-cell spatial pharmacobiology identifies conserved stromal barriers to therapeutic antibody delivery in human solid tumors go.nature.com/4atBJML
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Aram Chung retweeted
Eric Topol
@EricTopol
May 1
In cancer, activated T cells release abundant extracellular vesicles that transfer DNA to the nucleus of tumor and immune (dendritic) cells, turning tumors from cold to hot. An immunotherapy in the works. @Cancer_Cell sciencedirect.com/science/ar… sciencedirect.com/science/ar…
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CAR-X cell engineering dlvr.it/TSG6WV
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A multiobjective AI model for LNP engineering enhances tissue-selective mRNA delivery go.nature.com/4ugPm9D
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Aram Chung retweeted
Science News@SciencNews
Apr 19
Macrophage senescence is a central driver of chronic inflammation in aging and metabolic liver disease, and a tractable therapeutic target.
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Aram Chung retweeted
Cell@CellCellPress
Apr 16
In the latest issue! Hallmarks of cancer—Then and now, and beyond dlvr.it/TS4Plc

Hallmarks of cancer—Then and now, and beyond

Hanahan revisits the evolving framework of cancer hallmarks, synthesizing 25 years of conceptual refinement into a multidimensional view of tumor biology. This review highlights how aberrant capabi...

cell.com
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A lysosomal barcoding strategy to quantify endosomal escape of nucleic acids in vivo assesses the performance of branched ionizable lipids for potent liver delivery #NBTNV go.nature.com/4s4X7P7 rdcu.be/fdfzQ
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Aram Chung retweeted
Eric Topol
@EricTopol
Mar 25
Steady progress towards engineering immune cells in the body now for refractory myeloma , with major implications for many autoimmune diseases and cancers nature.com/articles/s41591-0… nature.com/articles/s41591-0…
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For readers interested in lipid nanoparticles for oligonucleotide delivery, here's an article covering 60 years of progress in the field rdcu.be/fb9xD nature.com/articles/s41573-0…
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Aram Chung retweeted
Eric Topol
@EricTopol
Apr 6
Cell senescence and how it predisposes to cancer, no less how we may be able to modulate it. An outstanding @CellCellPress review cell.com/cell/fulltext/S0092…
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