Years ago, I treated an MS patient who had Lyme causing his illness. He was disabled, with lots of demyelination on his MRI's. Happily, he responded well to long term antimicrobials, got off disability, and had dramatic resolution of most of the demyelinating lesions in his brain and spine. His neurologist at first refused to accept it, kept writing "chronic Lyme" in quotes in the medical notes, to imply that it was a fictitious condition (docs can be so petty). He attributed the improvements to spontaneous remission for the first year or so, but after a while he begrudgingly admitted that the antimicrobials must have helped. Literally 20 years later I had a patient with that same neurologist. She had a diagnosis of possible MS, wasn't disabled, but had very significant quality of life impairments due to numbness and weakness. I found evidence of Lyme so I treated her too. And happily her neurologic symptoms resolved by more than 95%. When I got a copy of her notes from that same neurologist, he was still putting "chronic Lyme" in quotes. Still refused to believe his patients as well as his own eyes. The moral of the story: Some docs are stubborn morons who will never change. Here's some info about Lyme & MS. No worries, the paywall is down for both parts 1 & 2. Hope it helps folks. zerospin.substack.com/p/mult…

Aug 6, 2026 · 12:16 AM UTC

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And here's the link to Part 2. In Part 1, I examine the current state of MS treatments and point out what I believe to be very material gaps in the science. in Part 2, I review decades of published evidence linking spirochetal infection to MS. (Spirochetes are a type of bacteria. For example Lyme bacteria are spirochetes.) zerospin.substack.com/p/ms-t…
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Replying to @StevePhillipsMD
This is incredible. We need to have an entire clinic full of those who think/practice like you Dr.
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Thank you. 😊
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Replying to @StevePhillipsMD
the only problem with science, is that humans are involved, making it subject to all the problems we bring along
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And that’s a very long list of problems.
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Replying to @StevePhillipsMD
Thank you for sharing doctor, you have no idea how excited I am to read this. My mom has MS and need to get smarter on the science so this is fantastic
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Replying to @StevePhillipsMD
To my knowledge, the correct term is "post-treatment lyme disease syndrome." The problem with "chronic Lyme" is when they no longer test positive yet are prescribed long-term antibiotics, risking antimicrobial resistance. If Abx work short-term for MS, may need new terminology.
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Replying to @StevePhillipsMD
Btw, @CassandraTesla you might enjoy this
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Replying to @StevePhillipsMD
@grok Borrelia (Lyme) infection has been shown to down regulate the vitamin D receptor. EBV infection also targets the vitamin D receptor. MS risk is increased in patients with vitamin D receptor polymorphisms. All of these infections / diseases have a reported relationship to antiphospholipid antibodies. Confirm this. Explain links. How does vitamin D deficiency and B12 deficiency (elevated Homocysteine) exacerbate this pathophysiology. How does this relate to neutrophil extracellular traps? Give detailed citations.
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Replying to @StevePhillipsMD
I see physicians in CME lectures describing their patient's dietary with phrases like, "in 20 years I've seen perhaps 2 patients lose significant amounts of weight and keep it off." And diabetes reversal just doesn't exist. Meanwhile I see patients weekly who have lost very significant amounts of weight, often without medication assistance. And a steady stream of people who have reversed or are progressing steadily towards diabetes reversal. Patients absolutely do listen to medical advice. Doctors who find their patients cannot lose weight or cannot reverse their diabetes are giving bad advise. Meat is medicine.
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Replying to @StevePhillipsMD
Does that mean that the definition of "chronic Lyme" means that "it is all in the patient's head?" This is the same silly nonsense they are now doing to the pain patients, as a way to deny proper, appropriate, clinically indicated opioid pain medication. Claiming that their documented, painful conditions "should have healed," that they "should not be having any pain," and that "opioids cause pain." And all this de-prescribing agenda has done is cause untold suffering and death. Even hospice patients are being denied pain medications - which was NEVER supposed to happen. I will be dropping a lawsuit about the fraudulent "public health emergency declaration in the opioid crisis" this fall: drive.google.com/file/d/1w11…
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Replying to @StevePhillipsMD
I was misdiagnosed w MS...my MRI literally stated patient's brain lesions could be caused by MS or Lyme...Lyme wasnt considered an option by my neurologist nevertheless, I chose the Lyme diagnosis and my neuro complications largely resolved w many months of abx
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My doctor who helped me recover from Lyme & Co had his license suspended because he was successfully treating someone with a prior MS diagnosis for Lyme. Neurologist found out & reported him. Brilliant, knowledgeable 70 year old doc was then lost to patients that needed him
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Replying to @StevePhillipsMD
The link between MS and infection was made in the 1950's. I've read the articles. The only reason I'm glad I became an MD, is so that I have been able to navigate some of the medical quagmire. Otherwise, I'm ashamed.
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Replying to @StevePhillipsMD
23 years it took the a-holes to admit I don't have MS. Now I'm on IVIG, 3antibiotics and an antiparasitic. The "Lyme Rage" I feel on a daily basis is unparalleled...
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Replying to @StevePhillipsMD
I've been censored and skipped over for years on this topic. I don't care about credit. I am glad it's finally coming out. Owndoc.com you can find it in the archives. They were decades ahead of most. I am so grateful for their work because I learned from that site. I built a treatment plan myself ;) measslainte.com/neurospiroch…
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Replying to @StevePhillipsMD
Dx with MS in 2015. My EBV count was over 600 so I decided to reduce the viral overload and was able to re-myelinate my nerves too. Got rid of all my symptoms in three years by balancing my body. I did it with antimicrobials, antivirals and antifungals, real food and changing lifestyle - no medicine. My neurologist was a world renowned MS researcher and he also didn’t believe in chronic Lyme. I believed Dr Alan MacDonald and read all his research on this. I’m now designing a clinical trial based on what I did in order to validate the techniques. Looking forward to reading your articles! I love discussing these things with like-minded people!
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Replying to @StevePhillipsMD
What were your antimicrobials of choice? Borrelia is popping up as well as bacteria from fleas. Covid seems to be awakening things throughout patients histories
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Replying to @StevePhillipsMD
4 NH MDs suspected I had MS in 2004, when I was actually a decade into Lyme, Babesia, & Bartonella from an almost fatal tick bite in 1994. Thank you for arresting the progression of MS symptoms - optic neuritis, trigeminal neuralgia, incapacitating fatigue…it was grueling.
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Replying to @StevePhillipsMD
I hate them (having dealt Lyme and mold MS/Parkinson's like symptoms).
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Replying to @StevePhillipsMD
How do you treat Lyme? I had it, took supplements and prescribed doxy 100mg BID 6 weeks, Ivm 12mg and methylene blue 50mg for two months. Cured mine. Now I'm battling it again after getting bit again!
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Replying to @StevePhillipsMD
Medical practice is fundamentally wrong. Most healthcare providers view the patients and their complaints as the problem (to be dealt with or ignored), instead of their illness.
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Replying to @StevePhillipsMD
After having “lupus” for 3 years I finally had a positive Lyme test after a bout of Bell’s Palsy and circular rashes all over my body, my rheumatologist told me how unlucky I was to have two autoimmune conditions. Anyway my “lupus” spontaneously resolved after 6 months of doxy.
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Replying to @StevePhillipsMD
Thank you for posting your articles on MS, Dr. Phillips. I had read these and bookmarked them a long time ago, but could not find where I saved them. lol Thank you, also, for being such an amazingly good doctor. You've been in the trenches with so many of us over the years.
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Replying to @StevePhillipsMD
Thank you for your work. I was dx'd with CIDP ten years ago. Curious if you see parallels between MS and CIDP. Since both involve demyelination (albeit peripheral vs. central), and MS is so much more prevalent/prominent, I've always followed MS developments as a potential proxy for advancements in CIDP. I undergo two IVIG infusions monthly (over 250 infusions to date) which seem to help - - - a little. Recently, my most debilitating symptom has been extreme, persistent fatigue, and I've now had several blood tests showing highly elevated levels of EBV antiGEN (not antiBODY). I've been advised to consult an immunologist. Two issues: 1. *Most* immunologists are basically glorified allergists 2. I have little confidence they could offer any treatment of net benefit My six-month check-in with a hematologist was met with his usual indifference. At this point I'm basically fed up with "conventional" doctors, so any advice or counsel would be greatly appreciated.
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Replying to @StevePhillipsMD
how do you treat the Lyme?
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Replying to @StevePhillipsMD
I just went over my MRI with Nuero who doesn’t believe in Lyme but I have had it for at least 20 years plus co infections. Says the lesions are not MS no big deal.
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Replying to @StevePhillipsMD
Stubborn morons? Yep.
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Replying to @StevePhillipsMD
What are your thoughts on managing histamine in a situation like this? Possibly a low histamine diet combined with something like quercetin & DAO?
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Replying to @StevePhillipsMD
To be fair, we often put quotations to flag that it's something the patient simply told us they have, rather than something confirmed. I do the same thing with people telling me they have "endometriosis", as the diagnosis is often nebulous without surgical confirmation. It's not that I'm being petty or don't believe them, I'm just not sure.
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Replying to @StevePhillipsMD
Thanks for sharing. I got infected with Lyme last year. Good so far, but you never know..
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Replying to @StevePhillipsMD
Very interesting! I was diagnosed w/ MS after a decade+ of health issues, & diagnosed with Pernicious Anemia (PA) in 2009. Docs focused on MS. Now years later I’ve discovered it was undiagnosed & then under treated PA. Daily b12 injections = lifesaving! Open to discussion!!
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Replying to @StevePhillipsMD
can you elaborate more on the actual cure? low-dose antibiotics?
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Replying to @StevePhillipsMD
That’s most docs unfortunately
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Replying to @StevePhillipsMD
Scientists just cracked the multiple sclerosis code after decades of searching. Two specific gut bacteria are triggering the disease, and they've proven it using identical twins and mice. This changes everything we know about MS:
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This is heartwarming. You have helped so many including my closest friends!
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